Opportunity Information: Apply for PAR 15 316
Apply for PAR 15 316
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition for the Renewal of the National Cell Repository of Alzheimers Disease (NCRAD) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Aug 27, 2015 and posted on Jul 31, 2015.
- Applicants must submit their applications by Sep 26, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $900,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Independent school districts City or township governments County governments Public housing authorities/Indian housing authorities Private institutions of higher education For profit organizations other than small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Small businesses Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply.Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The opportunity titled "Limited Competition for the Renewal of the National Cell Repository of Alzheimers Disease (NCRAD) (U24)" is a National Institutes of Health (NIH), National Institute on Aging (NIA) funding announcement that supports the continued operation and renewal of an existing national biomedical resource focused on Alzheimers disease. The project being renewed is the National Cell Repository for Alzheimers Disease (NCRAD), which, as the name suggests, is a centralized repository intended to collect, manage, and distribute biological materials that are especially valuable for research on Alzheimers disease and related aging topics. The mechanism is a U24 cooperative agreement, which typically indicates that the awardee will carry out the work in close collaboration with NIH program staff, with substantial federal involvement in certain aspects of governance, oversight, coordination, and/or milestone-based management compared with a standard grant.
This is described as a limited competition renewal. In practice, that wording signals that the announcement is primarily aimed at renewing an ongoing, already-supported cooperative agreement rather than creating a brand-new program competed broadly among entirely new applicants. The intent is continuity of a national service resource that the research community relies on, rather than funding a short-term research project. The goal is to ensure NCRAD remains available, functional, and responsive to the needs of investigators by maintaining the infrastructure required to receive biological specimens, process and store them under appropriate quality systems, curate and track associated data, and distribute materials to qualified researchers in a way that supports reproducibility and broad scientific use.
From an administrative and budgeting standpoint, the announcement falls under the discretionary funding category, uses the cooperative agreement funding instrument, and is aligned with the health activity category. The CFDA listing provided is 93.866, Aging Research. The opportunity explicitly states there is no cost sharing or matching requirement, meaning applicants are not required to contribute a defined portion of project costs from non-federal sources as a condition of the award. The award ceiling is listed as $900,000, which reflects the maximum amount anticipated per award under the terms of the announcement; this level is consistent with the kinds of ongoing operational costs required to run a national repository, including specialized personnel, laboratory operations, specimen storage, informatics systems, compliance, shipping, and user support.
Key dates show that the funding announcement was posted on July 31, 2015, with a creation date of August 27, 2015. The original closing date is listed as January 7, 2018, but the current closing date is September 26, 2017, and the archive date is October 26, 2017. The presence of both original and current closing dates indicates the solicitation timeline was revised at some point, and "archived" indicates the announcement is no longer open for application submission after the final closeout period. These dates matter mainly for historical context and for understanding when the renewal competition occurred.
Eligibility is broad on paper and includes a wide range of domestic U.S. organizations across the nonprofit, for-profit, government, and academic spectrum. Specifically listed eligible applicants include nonprofits with and without 501(c)(3) status (other than institutions of higher education), public and private institutions of higher education, small businesses, for-profit organizations other than small businesses, and multiple levels of government (city/township, county, state, special district governments, independent school districts, and certain housing authorities). The announcement also enumerates additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), along with eligible federal agencies, faith-based or community-based organizations, regional organizations, tribal governments and tribal organizations (including those other than federally recognized), and U.S. territories or possessions. At the same time, the announcement is clear that foreign participation is not allowed in this competition: non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined in the NIH Grants Policy Statement are not allowed. In other words, the infrastructure and awardee organization must be entirely domestic.
Because this is a U24 cooperative agreement renewal of a major repository, the underlying expectations typically revolve around sustaining and improving core repository functions rather than generating a single set of research findings. While the short description in the provided text does not enumerate specific tasks, the nature of a national cell repository generally implies responsibilities such as standardized acquisition and handling of biospecimens, long-term storage under validated conditions, robust chain-of-custody and inventory management, strong bioinformatics and database support for sample tracking and associated metadata, quality assurance and quality control procedures, adherence to ethical and regulatory requirements for human-derived materials, and efficient distribution workflows so that investigators can access well-characterized materials for Alzheimers disease research. The cooperative agreement structure also commonly involves regular reporting, coordination meetings, and alignment with NIA priorities to ensure the repository continues to serve as a reliable, high-impact research enablement platform for the aging and dementia research community.
The sponsoring agency is NIH, and the lead institute is the National Institute on Aging. The funding opportunity number is PAR-15-316, and the public information link provided for the full announcement is http://grants.nih.gov/grants/guide/pa-files/PAR-15-316.html. For technical problems accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is a support contact for electronic access issues rather than a scientific or grants management point of contact.
FAQs: Limited Competition for the Renewal of the National Cell Repository of Alzheimers Disease (NCRAD) (U24) - PAR-15-316
What is this funding opportunity?
This opportunity is an NIH National Institute on Aging (NIA) funding announcement titled "Limited Competition for the Renewal of the National Cell Repository of Alzheimers Disease (NCRAD) (U24)." It supports the continued operation and renewal of the National Cell Repository for Alzheimers Disease (NCRAD), a centralized national biomedical resource for Alzheimer's disease research.
What is the main purpose of NCRAD under this announcement?
The purpose is to maintain NCRAD as a functional, responsive national service resource by sustaining the infrastructure needed to receive, process, store, curate, track, and distribute biological materials and associated data that are valuable for Alzheimer's disease and related aging research.
What does "limited competition" mean here?
"Limited competition" indicates the announcement is primarily intended to renew an ongoing, already-supported cooperative agreement rather than to establish an entirely new program competed broadly among new applicants. The focus is continuity of a national repository resource relied upon by the research community.
What is the funding mechanism?
The mechanism is a U24 cooperative agreement. This typically means the awardee performs the work in close collaboration with NIH program staff, with substantial federal involvement in areas such as governance, oversight, coordination, and/or milestone-based management compared with a standard grant.
Who is the sponsoring agency and lead institute?
The sponsoring agency is the National Institutes of Health (NIH), and the lead institute is the National Institute on Aging (NIA).
What is the funding opportunity number?
The funding opportunity number is PAR-15-316.
Where can applicants find the full announcement?
The public link provided for the full announcement is: http://grants.nih.gov/grants/guide/pa-files/PAR-15-316.html
What is the CFDA listing and program area?
The CFDA listing provided is 93.866, Aging Research. The opportunity aligns with the health activity category.
Is cost sharing or matching required?
No. The opportunity explicitly states there is no cost sharing or matching requirement.
What is the award ceiling?
The award ceiling is listed as $900,000, reflecting the maximum amount anticipated per award under the announcement.
What kinds of costs does the announcement suggest the budget supports?
Based on the description of NCRAD as a national repository, the budget level is consistent with ongoing operational costs such as specialized personnel, laboratory operations, specimen storage, informatics systems, compliance activities, shipping, and user support.
When was the opportunity posted and created?
The announcement was posted on July 31, 2015, and the creation date is listed as August 27, 2015.
What were the closing dates and what do they indicate?
The original closing date is listed as January 7, 2018, while the current closing date is September 26, 2017. The presence of both suggests the solicitation timeline was revised at some point.
Is the opportunity still open?
No. The archive date is October 26, 2017, and the announcement is described as archived, meaning it is no longer open for application submission after the final closeout period.
What types of organizations are eligible to apply?
Eligibility is broadly described as including many U.S. domestic organization types across nonprofit, for-profit, government, and academic sectors. Examples explicitly listed include:
- Nonprofits with or without 501(c)(3) status (other than institutions of higher education)
- Public and private institutions of higher education
- Small businesses
- For-profit organizations other than small businesses
- City/township, county, state, and special district governments
- Independent school districts
- Public housing authorities/Indian housing authorities (as listed)
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving Institutions
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISISs)
- Faith-based or community-based organizations
- Regional organizations
- Tribal governments and tribal organizations (including those other than federally recognized)
- U.S. territories or possessions
- Eligible federal agencies (as listed)
Are foreign (non-U.S.) organizations eligible?
No. Foreign participation is not allowed. Non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed.
What does "no foreign components" mean in this context?
It means the infrastructure and awardee organization must be entirely domestic, and foreign components as defined by NIH policy are not permitted under this competition.
What is the focus of the work supported by this award?
The focus is sustaining and improving core repository functions rather than producing a single, short-term research project. The description emphasizes maintaining NCRAD as a long-running service resource for the research community.
What repository functions are implied by the announcement description?
While specific tasks are not enumerated line-by-line in the provided summary, the nature of a national cell repository implies functions such as standardized acquisition and handling of biospecimens, long-term storage under validated conditions, chain-of-custody and inventory management, database and informatics support for tracking samples and metadata, quality assurance/quality control procedures, adherence to ethical and regulatory requirements for human-derived materials, and distribution workflows that enable qualified investigators to access materials.
What does the cooperative agreement structure imply for award management?
It commonly implies regular reporting, coordination meetings, and alignment with NIA priorities, with substantial NIH involvement in oversight and coordination to ensure the repository continues to meet community needs.
What category of funding is this?
The announcement is described as discretionary funding and uses the cooperative agreement funding instrument.
Who should be contacted for technical issues with the announcement link or access?
For technical problems accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact a scientific or grants management contact?
No. The provided contact is described as support for electronic access issues rather than a scientific or grants management point of contact.
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