Opportunity Information: Apply for RFA HL 17 005

  • The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Limited Competition: Pediatric Heart Network for the Data Coordinating Center (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837,.
  • This funding opportunity was created on Dec 02, 2015 and posted on Dec 02, 2015.
  • Applicants must submit their applications by Mar 02, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education.
Apply for RFA HL 17 005

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Opportunity Summary:

The Limited Competition: Pediatric Heart Network for the Data Coordinating Center (U24) funding opportunity (RFA HL 17 005) is a discretionary NIH cooperative agreement designed to support the Data Coordinating Center (DCC) for the Pediatric Heart Network (PHN). The PHN is a multicenter clinical research collaboration focused on improving health outcomes and quality of life for people affected by heart disease that begins in childhood, particularly children and adults with congenital heart disease as well as children with acquired heart disease. In this structure, the DCC serves as the central hub that enables multiple clinical sites to work together effectively on shared research studies.

This announcement is a limited competition, meaning eligibility is restricted to a single entity: only the current PHN Data Coordinating Center awardee is allowed to apply. While the eligible applicant types listed include public and state-controlled institutions of higher education and private institutions of higher education, the practical eligibility constraint is that the applicant must be the incumbent DCC. The intent is continuity of operations and expertise for an established network coordination function rather than opening the competition to new entrants.

The core purpose of the award is to maintain and operate the DCC in partnership with the PHN Clinical Research Centers and other stakeholders to support multicenter collaborative clinical research. That collaboration is meant to make large, rigorous studies feasible across institutions, allowing the network to evaluate medical, interventional, and surgical therapies in a coordinated way. By pooling patients, standardizing protocols, and using common data systems and analytic approaches, the PHN can answer questions that would be difficult or impossible for a single center to address on its own, especially in conditions that may be relatively uncommon at individual hospitals.

Beyond supporting clinical trials and other multicenter studies, the network model described in the FOA emphasizes broader capacity building and field advancement. The PHN infrastructure is positioned as a training platform for fellows, junior faculty, and nurses, giving developing clinicians and investigators hands-on experience with high-quality multicenter research. The collaborative environment also supports the development of new techniques and methodologies, which can include improved study designs, better outcome measures, innovative approaches to data collection, and analytic strategies tailored to pediatric and congenital cardiology populations. Finally, a key expectation is dissemination: results and lessons learned are intended to be shared so they can strengthen the scientific foundation for caring for affected individuals and ultimately improve clinical practice.

Administratively, the opportunity is issued by the U.S. Department of Health and Human Services, National Institutes of Health (listed as HHS-NIH11), and is associated with the health funding activity category. The CFDA numbers attached to the announcement are 93.837 (and also listed are 93.837 again), reflecting its placement within NIH cardiovascular and related research assistance programs. The FOA was posted and created on December 2, 2015, with an original and current application closing date of March 2, 2016. The anticipated number of awards is one, consistent with the single-incumbent eligibility and the nature of a centralized coordinating center. The award ceiling is not specified in the provided source data.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This opportunity is the "Limited Competition: Pediatric Heart Network for the Data Coordinating Center (U24)" under RFA HL 17 005. It is an NIH cooperative agreement intended to support the Data Coordinating Center (DCC) for the Pediatric Heart Network (PHN).

Which agency is offering this award?

The opportunity is issued by the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), listed as HHS-NIH11.

What type of award mechanism is this?

It is a discretionary NIH cooperative agreement (U24). The description emphasizes a cooperative structure supporting a network-wide coordinating function.

What is the Pediatric Heart Network (PHN)?

The PHN is a multicenter clinical research collaboration focused on improving health outcomes and quality of life for people affected by heart disease that begins in childhood. This includes children and adults with congenital heart disease, as well as children with acquired heart disease.

What is the role of the Data Coordinating Center (DCC) in the PHN?

The DCC serves as the central hub that enables multiple clinical sites to work together effectively on shared research studies. It supports the coordination needed for multicenter collaborative clinical research across the network.

What is the main purpose of this award?

The core purpose is to maintain and operate the PHN Data Coordinating Center in partnership with PHN Clinical Research Centers and other stakeholders to support multicenter collaborative clinical research.

Why is this a "limited competition"?

This announcement is a limited competition because eligibility is restricted to a single entity. Only the current PHN Data Coordinating Center awardee is allowed to apply. The stated intent is continuity of operations and expertise for an established network coordination function rather than opening competition to new applicants.

Who is eligible to apply?

While the eligible applicant types listed include public and state-controlled institutions of higher education and private institutions of higher education, the practical eligibility constraint is that the applicant must be the incumbent (current) PHN Data Coordinating Center awardee.

How many awards are expected to be made?

The anticipated number of awards is one, which aligns with the single-incumbent eligibility and the centralized nature of a network Data Coordinating Center.

What kinds of research activities does the PHN support through this coordination?

The network is described as enabling large, rigorous studies across institutions, including the evaluation of medical, interventional, and surgical therapies in a coordinated way. By pooling patients, standardizing protocols, and using common data systems and analytic approaches, the network can address questions that may be difficult for a single center to answer on its own.

Why is a multicenter network approach important for this field?

The opportunity highlights that pooling patients across institutions helps make studies feasible, especially when conditions are relatively uncommon at individual hospitals. Standardized protocols and shared data systems also support consistency and rigor across participating sites.

Does the FOA emphasize activities beyond multicenter studies?

Yes. The description emphasizes broader capacity building and field advancement, including serving as a training platform and supporting development of new techniques and methodologies.

How does the PHN infrastructure support training?

The PHN infrastructure is positioned as a training platform for fellows, junior faculty, and nurses, providing hands-on experience with high-quality multicenter research.

What kinds of methodological improvements are expected or encouraged?

The opportunity notes the collaborative environment can support development of improved study designs, better outcome measures, innovative approaches to data collection, and analytic strategies tailored to pediatric and congenital cardiology populations.

Is dissemination of results part of the expectations?

Yes. A key expectation described is dissemination: results and lessons learned are intended to be shared to strengthen the scientific foundation for care and to improve clinical practice.

What is the funding activity category for this opportunity?

The opportunity is associated with the health funding activity category.

What CFDA number(s) are associated with this opportunity?

The CFDA number attached to the announcement is 93.837 (also listed again as 93.837 in the provided information), reflecting its placement within NIH cardiovascular and related research assistance programs.

When was the FOA posted and created?

The FOA was posted and created on December 2, 2015.

What was the application closing date?

The original and current application closing date listed is March 2, 2016.

Is the award ceiling (maximum funding amount) provided?

No. The award ceiling is not specified in the provided source data.

What does the DCC partnership structure include?

The DCC is intended to operate in partnership with the PHN Clinical Research Centers and other stakeholders to support network-wide collaboration on multicenter studies.

Who benefits from the PHN's work, as described in the opportunity?

The stated focus is on improving outcomes and quality of life for people affected by heart disease that begins in childhood, including individuals with congenital heart disease (children and adults) and children with acquired heart disease.

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