Opportunity Information: Apply for PAR 12 008
Apply for PAR 12 008
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition Revision(s) to the Dominantly Inherited Alzheimer Network (U19)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Nov 8, 2011 and posted on Nov 8, 2011.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "Limited Competition Revision(s) to the Dominantly Inherited Alzheimer Network (U19)" (Funding Opportunity Number PAR-12-008) is a National Institutes of Health (NIH) discretionary funding announcement that supports revisions to an existing, funded cooperative agreement connected to the Dominantly Inherited Alzheimer Network (DIAN). DIAN is an NIH-supported research effort focused on dominantly inherited (familial) forms of Alzheimer disease, and this particular announcement is not for brand-new standalone projects. Instead, it is designed for applicants who already hold the parent DIAN U19 award and want to request additional funds or make other allowable changes through a formal "revision" application, consistent with NIH policies for revisions (often used to add scope, accelerate progress, or address newly emerging needs within the boundaries of the parent award).
The funding mechanism is a Cooperative Agreement (U19), which generally means NIH expects substantial programmatic involvement during the conduct of the project. In practical terms, a cooperative agreement often includes closer coordination with NIH program staff than a standard research project grant, and it is commonly used for large, multi-component, collaborative research programs where NIH involvement can help align activities, coordinate network functions, and ensure shared goals and milestones are met.
A key limitation in this announcement is that revision applications may not request support beyond the project end date of the parent award. That restriction matters because it effectively caps the timeline: even if the revision proposes new activities, the requested budget period must fit entirely within the remaining approved project period of the currently funded DIAN U19. So the revision is meant to enhance or modify the ongoing program rather than extend it.
This opportunity falls under the NIH funding activity category of Health and is associated with CFDA 93.866 (Aging Research). There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving the award, though standard NIH budget rules and allowability requirements still apply.
Eligibility is limited and somewhat specialized. The announcement indicates that eligibility is restricted (a "limited competition"), and the eligible applicant category is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)." In addition, the announcement explicitly prohibits foreign involvement in several forms: non-U.S. (foreign) institutions cannot apply; non-U.S. components of U.S. organizations are not eligible; and foreign components, as defined by the NIH Grants Policy Statement, are not allowed. Taken together, those restrictions mean the applicant organization and the supported project components must be domestic, with no foreign components included under NIH definitions.
In terms of timing, the opportunity was posted and created on November 8, 2011. The original and current closing date was September 7, 2013, and the archive date was October 8, 2013, indicating the announcement is no longer active for new submissions under that FOA. For historical reference and full details, the announcement was linked through the NIH Grants Guide (http://grants.nih.gov/grants/guide/pa-files/PAR-12-008.html). The contact information provided is primarily technical support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues (FBOWebmaster@OD.NIH.GOV), rather than a scientific or grants management point of contact.
Overall, PAR-12-008 was a time-limited NIH call for revision applications tied specifically to the DIAN U19 cooperative agreement, aimed at enabling existing DIAN awardees to propose additional or modified work within the remaining project period, under NIH cooperative agreement oversight, and with strict domestic-only participation rules.
Frequently Asked Questions (FAQs)
What is the official title and funding opportunity number for this grant?
The opportunity is titled "Limited Competition Revision(s) to the Dominantly Inherited Alzheimer Network (U19)" and the Funding Opportunity Number is PAR-12-008.
What is the purpose of PAR-12-008?
This announcement supports revision applications to an existing, funded cooperative agreement connected to the Dominantly Inherited Alzheimer Network (DIAN). It is intended for current DIAN U19 awardees who want to request additional funds or propose other allowable changes through a formal NIH "revision" application.
Is this opportunity for brand-new, standalone research projects?
No. The announcement is not for new standalone projects. It is specifically for revisions to an already funded parent DIAN U19 award.
Who is this funding opportunity meant for?
It is designed for applicants who already hold the parent DIAN U19 cooperative agreement award and are seeking to modify or enhance the funded program through a revision request, consistent with NIH revision policies.
What does "limited competition" mean in this context?
"Limited competition" indicates eligibility is restricted. The eligible applicant category is shown as "Others (see text field entitled Additional Information on Eligibility for clarification)," and the narrative description makes clear it is tied to the existing DIAN U19 parent award.
What is the funding mechanism used for this opportunity?
The mechanism is a Cooperative Agreement (U19).
What does a Cooperative Agreement (U19) imply about NIH involvement?
A cooperative agreement generally means NIH expects substantial programmatic involvement during the conduct of the project. In practice, it often involves closer coordination with NIH program staff than a standard research project grant, and it is commonly used for large, collaborative, multi-component programs such as research networks.
What is the Dominantly Inherited Alzheimer Network (DIAN)?
DIAN is an NIH-supported research effort focused on dominantly inherited (familial) forms of Alzheimer disease.
Can a revision application extend the project beyond the parent award end date?
No. A key limitation is that revision applications may not request support beyond the project end date of the parent award. Any proposed revision activities and requested budget period must fit entirely within the remaining approved project period of the current DIAN U19.
Does this FOA allow applicants to add scope or accelerate progress?
The announcement describes revisions as being consistent with NIH revision policies, which are often used to add scope, accelerate progress, or address newly emerging needs, as long as those changes remain within the boundaries of the parent award.
What is the NIH funding activity category for this opportunity?
The funding activity category listed is Health.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA 93.866 (Aging Research).
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Are foreign institutions eligible to apply?
No. Non-U.S. (foreign) institutions cannot apply under this announcement.
Are non-U.S. components of U.S. organizations eligible?
No. The announcement states that non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed in any form?
No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed.
What do the domestic-only rules mean for applicants in practical terms?
Based on the restrictions listed, the applicant organization and the supported project components must be domestic, and the application may not include foreign components under NIH definitions.
When was this opportunity posted and created?
The opportunity was posted and created on November 8, 2011.
What were the closing date and archive date?
The closing date (original and current) was September 7, 2013, and the archive date was October 8, 2013.
Is PAR-12-008 still active for new submissions?
No. The listed closing date and archive date indicate the announcement is no longer active for new submissions under this FOA.
Where was the full announcement hosted for reference?
It was linked through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-12-008.html.
What contact information is provided in the opportunity description?
The contact information provided is for technical support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues: FBOWebmaster@OD.NIH.GOV.
Does the listed contact appear to be a scientific or grants management contact?
No. The contact given is described as technical support for access or linking issues, rather than a scientific or grants management point of contact.
What is the main takeaway about what PAR-12-008 funded?
It was a time-limited NIH call for revision applications tied specifically to the DIAN U19 cooperative agreement, allowing existing DIAN awardees to propose additional or modified work within the remaining project period, under NIH cooperative agreement oversight, with strict domestic-only participation rules.
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