Opportunity Information: Apply for RFA RM 16 003
Apply for RFA RM 16 003
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Technologies to Understand the Control of Organ Function by the Peripheral Nervous System (OT2)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310,.
- This funding opportunity was created on Feb 08, 2016 and posted on Feb 08, 2016.
- Applicants must submit their applications by Sep 29, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
This funding opportunity, RFA-RM-16-003, is a National Institutes of Health (NIH) Common Fund SPARC program announcement that supports a limited competition for two-year technology development projects focused on the peripheral nervous system and how it controls organ function. SPARC stands for "Stimulating Peripheral Activity to Relieve Conditions," and the central goal of this initiative is to accelerate the development of tools that make it possible to map, measure, and understand the neural pathways and physiological mechanisms by which autonomic and peripheral nerves regulate organs in both healthy and diseased states. The bigger picture behind the program is translational: by improving the scientific understanding of peripheral nerve-organ communication, the work is intended to lay the groundwork for next-generation neuromodulation therapies, meaning treatments that intentionally change nerve activity (for example, through electrical stimulation or other approaches) to improve organ function and relieve disease.
The projects supported under this announcement are specifically framed as technology-focused efforts. Rather than funding general hypothesis-driven biology alone, the emphasis is on creating new tools or meaningfully improving existing ones so researchers can better elucidate peripheral neurobiology and neurophysiology. In practice, this can include technologies that enable more precise neural mapping, improved recording or stimulation capabilities, better anatomical or functional tracing of nerve circuits, new sensors or imaging methods that reveal how peripheral nerves interact with organs, or computational and analytical approaches that help interpret complex peripheral nervous system data. A key expectation is that these deliverables will directly facilitate SPARC neural mapping activities and strengthen the broader research community's ability to study autonomic control of organs.
A defining feature of this FOA is that it is a limited competition tied to a two-step process. Applicants cannot apply directly unless they have already participated in and successfully advanced through the corresponding OT1 pre-application stage (referenced as RFA-RM-16-002) and then received an invitation to submit an OT2 application. In other words, eligibility to submit is not open to the general public at the OT2 stage; it depends on prior selection and invitation based on the OT1 pre-application competition.
Administratively, the opportunity is categorized as discretionary grant funding in the health area and is associated with CFDA number 93.310. The sponsoring agency is the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH). The eligible applicant pool is broad and includes many common research-performing organizations and partners: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education in those nonprofit categories as specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the announcement's additional eligibility guidance.
Key timing information in the source data indicates the announcement was created and posted on February 8, 2016, with an application closing date of September 29, 2016 (original and current closing dates match). The source excerpt does not list an award ceiling or expected number of awards, suggesting those details were either not provided in the summarized fields or were specified elsewhere in the full FOA documentation. Overall, the announcement supports targeted, time-limited technology development intended to expand the technical foundation needed to understand peripheral control of organs and to accelerate progress toward practical neuromodulation-based interventions.
FAQs: NIH Common Fund SPARC Technology Development (RFA-RM-16-003)
What is the funding opportunity RFA-RM-16-003?
RFA-RM-16-003 is a National Institutes of Health (NIH) Common Fund SPARC program funding opportunity that supports a limited competition for two-year technology development projects focused on the peripheral nervous system and how it controls organ function.
What does SPARC stand for, and what is the program trying to achieve?
SPARC stands for "Stimulating Peripheral Activity to Relieve Conditions." The central goal is to accelerate development of tools that make it possible to map, measure, and understand the neural pathways and physiological mechanisms by which autonomic and peripheral nerves regulate organs in both healthy and diseased states.
What is the broader purpose of SPARC beyond basic research?
The larger, translational purpose is to improve scientific understanding of peripheral nerve-organ communication so the field can lay groundwork for next-generation neuromodulation therapies. These are treatments intended to change nerve activity (for example, through electrical stimulation or other approaches) to improve organ function and relieve disease.
What type of projects does this announcement support?
This announcement supports technology-focused development projects. The emphasis is on creating new tools or meaningfully improving existing ones that help researchers elucidate peripheral neurobiology and neurophysiology, rather than supporting general hypothesis-driven biology alone.
What kinds of technologies are in scope for this FOA?
Examples of technologies described as in scope include tools for more precise neural mapping, improved recording or stimulation capabilities, better anatomical or functional tracing of nerve circuits, new sensors or imaging methods that reveal how peripheral nerves interact with organs, and computational or analytical approaches for interpreting complex peripheral nervous system data.
How are expected deliverables described?
A key expectation is that deliverables will directly facilitate SPARC neural mapping activities and strengthen the broader research community's ability to study autonomic control of organs.
Is this an open competition?
No. This is a limited competition tied to a two-step process. Applicants cannot apply directly at this stage unless they have already participated in the corresponding OT1 pre-application stage (RFA-RM-16-002) and then received an invitation to submit an OT2 application.
What is required to be eligible to submit an application under RFA-RM-16-003?
Eligibility to submit at the OT2 stage depends on prior selection and invitation. An organization must have successfully advanced through the OT1 pre-application competition referenced as RFA-RM-16-002 and must have received an invitation to submit an OT2 application.
What is the project period for awards under this announcement?
The projects supported under this announcement are two-year technology development projects.
Which agency sponsors this opportunity?
The sponsoring agency is the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH), under the NIH Common Fund SPARC program.
How is the funding categorized?
The opportunity is categorized as discretionary grant funding in the health area.
What is the CFDA number associated with this opportunity?
The CFDA number associated with this opportunity is 93.310.
Who is eligible to apply (assuming they have an invitation)?
The eligible applicant pool is broad and includes: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education in those nonprofit categories as specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the announcement's additional eligibility guidance.
When was the announcement posted?
The source data indicates the announcement was created and posted on February 8, 2016.
What is the application deadline?
The application closing date in the source data is September 29, 2016 (the original and current closing dates match).
Is information provided on an award ceiling or the expected number of awards?
No. The provided source excerpt does not list an award ceiling or an expected number of awards, which suggests those details were not included in the summarized fields or were specified elsewhere in the full FOA documentation.
What scientific area does this FOA focus on?
The focus is the peripheral nervous system, including autonomic and peripheral nerves, and how these nerves regulate organ function in both healthy and diseased states.
How does this FOA connect to neuromodulation?
By improving tools to map and understand peripheral nerve-organ communication, the work is intended to accelerate progress toward practical neuromodulation-based interventions that intentionally alter nerve activity to improve organ function and relieve disease.
Does this FOA emphasize technology development over traditional biological discovery?
Yes. The projects are specifically framed as technology-focused efforts. The emphasis is on developing or significantly improving tools that enable better mapping, measurement, and interpretation of peripheral nervous system activity related to organ control.
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