Opportunity Information: Apply for PA 16 178
Apply for PA 16 178
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Limited Competition: Tissue Chips and Missing Organs (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.350,.
- This funding opportunity was created on Apr 08, 2016 and posted on Apr 08, 2016.
- Applicants must submit their applications by Apr 22, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The NIH opportunity titled "Limited Competition: Tissue Chips and Missing Organs (Admin Supp)" (PA-16-178) is an administrative supplement grant designed specifically for teams already participating in the NIH Tissue Chip (TC) Program. Its central goal is to strengthen and broaden the existing Tissue Chip Consortium by providing extra, targeted funds to build "missing" organ microphysiological systems, meaning organ platforms that are not yet part of the consortium at all or are meaningfully under-represented compared to other organ models. In practical terms, NIH is trying to fill gaps in the consortium's portfolio so the overall program better reflects the range of human organ functions needed for more complete drug efficacy and toxicity testing.
This is a limited competition, which means it is not open to the entire research community in the usual way. It is intended for investigators and institutions that already hold awards under a specific earlier solicitation: RFA-RM-11-022, "Integrated Microphysiological Systems for Drug Efficacy and Toxicity Testing in Human Health and Disease (UH2/UH3)." Only current awardees under that program mechanism are being invited to apply for these supplemental funds, and the supplement is meant to add work that is closely aligned with, and builds upon, the currently funded Tissue Chip projects rather than launching an unrelated new research direction.
The funding instrument is a grant and the category is listed as discretionary, with the activity area broadly in health. The award ceiling is $50,000, indicating these supplements are relatively small, focused infusions of support intended to accelerate development work, fill a specific technical or biological gap, or create an initial version of an underrepresented organ platform that can be integrated into the broader consortium effort. While the listing does not specify the number of expected awards, the design and cap suggest an intent to fund multiple small expansions across the consortium where clear needs exist.
Eligibility, as presented in the source data, includes a wide range of organization types such as various levels of government, public and private higher education institutions, tribal governments and organizations, nonprofits (with and without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses. However, the critical practical eligibility limiter is the "limited competition" requirement: applicants must be investigators/institutions already funded through the NIH Tissue Chip Program under the specified UH2/UH3 award initiative. In other words, the broad organizational eligibility list is secondary to the requirement that the applicant already be part of the relevant NIH Tissue Chip funding cohort.
The opportunity was posted and created on April 8, 2016, with an application due date of April 22, 2016, indicating a short turnaround typical of some administrative supplement announcements. The sponsoring agency is HHS/NIH (listed as HHS-NIH11), and the CFDA numbers associated with the opportunity are 93.350. Overall, PA-16-178 is best understood as a focused NIH effort to quickly add coverage for missing organ systems within an existing, coordinated tissue chip program, using modest supplemental awards to extend and balance the consortium's organ-model capabilities for drug testing applications.
FAQs: NIH "Limited Competition: Tissue Chips and Missing Organs (Admin Supp)" (PA-16-178)
What is PA-16-178?
PA-16-178, titled "Limited Competition: Tissue Chips and Missing Organs (Admin Supp)," is an NIH administrative supplement opportunity intended to provide additional, targeted funds to existing projects within the NIH Tissue Chip (TC) Program.
What is the main purpose of this administrative supplement?
The central purpose is to strengthen and broaden the existing Tissue Chip Consortium by supporting development of "missing" organ microphysiological systems. These are organ platforms that are not currently represented in the consortium at all, or are meaningfully under-represented compared to other organ models.
What does NIH mean by "missing organs" in this context?
"Missing organs" refers to organ microphysiological systems (organ platforms/tissue chips) that the current consortium does not include, or includes in a limited way relative to other organ models. The intent is to fill gaps so the overall portfolio covers a wider range of human organ functions.
Why is NIH offering this supplement?
Based on the opportunity description, NIH is aiming to balance and expand the consortium's organ-model capabilities so the program better reflects the range of human organ functions needed for more complete drug efficacy and toxicity testing.
Is this opportunity open to the general research community?
No. This is a limited competition and is not open to the broader research community in the typical way.
Who is eligible to apply under the limited competition requirement?
Only investigators and institutions that already hold awards under the earlier solicitation RFA-RM-11-022, "Integrated Microphysiological Systems for Drug Efficacy and Toxicity Testing in Human Health and Disease (UH2/UH3)," are invited to apply for these supplemental funds.
Does the broad organizational eligibility list mean any organization can apply?
No. While the source data lists many eligible organization types (including various government entities, higher education institutions, tribal governments and organizations, nonprofits, for-profits, and small businesses), the practical limiter is the limited competition requirement. Applicants must already be participating awardees in the specified NIH Tissue Chip UH2/UH3 program cohort.
What is the relationship between the supplement work and an existing Tissue Chip award?
The supplement is meant to add work that is closely aligned with and builds upon currently funded Tissue Chip projects, rather than starting an unrelated new research direction.
What type of funding instrument is PA-16-178?
The funding instrument is a grant.
What is the activity area for this opportunity?
The activity area is broadly in health.
What is the maximum award amount?
The award ceiling is $50,000.
What does the $50,000 award ceiling suggest about the scope of work?
The ceiling indicates these are relatively small, focused supplements intended to accelerate development, fill a specific technical or biological gap, or create an initial version of an underrepresented organ platform that can be integrated into the broader consortium effort.
How many awards does NIH expect to make?
The listing does not specify the expected number of awards.
When was the opportunity posted?
The opportunity was posted (and created) on April 8, 2016.
What is the application due date?
The application due date is April 22, 2016.
How much time was available between posting and the due date?
Based on the provided dates (April 8, 2016 to April 22, 2016), the turnaround was short, which is described as typical of some administrative supplement announcements.
Which federal agency sponsors this opportunity?
The sponsoring agency is HHS/NIH (listed as HHS-NIH11).
What CFDA number is associated with this opportunity?
The CFDA number associated with the opportunity is 93.350.
How should PA-16-178 be understood in practical terms?
It is a focused NIH effort to quickly add coverage for missing organ systems within an existing, coordinated Tissue Chip program using modest supplemental awards to extend and balance the consortium's organ-model capabilities for drug testing applications.
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Previous opportunity: Limited Competition: Tissue Chips for Rare Diseases (Admin Supp)
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