Opportunity Information: Apply for PAR 10 261
Apply for PAR 10 261
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Pilot for NIGMS Legacy Community Wide Scientific Resources (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Aug 16, 2010 and posted on Aug 16, 2010.
- Applicants must submit their applications by Oct 26, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Eligible Agencies of the Federal Government Non domestic (non U.S.) Entities (Foreign Organizations).
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Opportunity Summary:
The Limited Pilot for NIGMS Legacy Community-Wide Scientific Resources (R24) grant opportunity (Funding Opportunity Number PAR-10-261) was a discretionary National Institutes of Health (NIH) funding announcement issued by the National Institute of General Medical Sciences (NIGMS). It was designed as a limited, transitional funding option to keep certain high-value, community-serving scientific resources running after their original NIGMS initiatives ended or after a resource award reached a non-renewable endpoint set by the original program (for example, when an initiative had a fixed duration and could not be extended under the same terms). The central idea was continuity: NIGMS wanted to prevent the sudden loss of important legacy resources that the research community depended on, even when the original funding mechanism was no longer available.
In this context, NIGMS defined a "resource" very specifically as a non-hypothesis-driven activity that provides broadly useful data, materials, tools, or services. These resources are meant to help a field move faster, with higher quality and better cost-efficiency, by supporting many investigators rather than advancing one research project’s specific scientific hypothesis. A key expectation is broad accessibility: the resource should be available to all investigators for clearly defined, well-understood purposes, meaning it cannot be effectively restricted to a small group or used primarily for a single lab’s research agenda. The program was aimed at resources that sit squarely within the NIGMS mission and directly benefit communities that NIGMS already supports through its grant portfolio.
NIGMS also set boundaries around what it would and would not support through this pilot. The institute indicated it would consider funding (including partial support) only for resources that were not supportable through other NIH institute or center initiatives and that were not yet self-sustaining, commercializable, or otherwise able to operate without federal support. In other words, the pilot was meant for resources that still needed help staying alive but were important enough to justify continued investment because of their demonstrated or strongly evidenced value to a broad research community. Just as important, this announcement was not intended to create new resources. It was strictly for continued support of existing legacy resources that had already been developed through prior NIGMS-supported activities.
The allowable scope of work was maintenance-focused rather than research-focused. Applicants were expected to request support for operating and maintaining the resource (such as ongoing curation, distribution, user support, routine updates, infrastructure upkeep, or other sustaining functions), not for hypothesis-driven research activities or major new development efforts. This distinction matters because NIGMS framed the resource as a shared scientific infrastructure, and the pilot’s goal was to keep that infrastructure functional and available, rather than to fund new experiments or exploratory science. Another major feature of the opportunity was its explicitly limited nature: because it was a pilot, NIGMS cautioned applicants and awardees that funding might not extend beyond the stated project period, so applicants needed to plan with the possibility that federal support could end after the award period.
The funding mechanism used was the NIH R24 grant mechanism, which is commonly used for resource-related projects and other specialized, community-benefiting activities. The announcement did not specify a fixed set-aside budget or a guaranteed number of awards. Instead, NIGMS stated that the total amount awarded and the number of awards would depend on the number of applications submitted, their scientific and programmatic quality, the requested duration, and the proposed costs. Cost sharing or matching was not required.
Eligibility was broad and included many organizational types: public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with 501(c)(3) status and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. The eligibility language also included other categories referenced in the full announcement text, and it explicitly noted additional eligible applicants such as eligible federal government agencies and non-U.S. (foreign) organizations. The funding activity category was health, and the associated CFDA number listed was 93.859 (Biomedical Research and Research Training).
Administratively, the opportunity was posted on August 16, 2010, with an original and final closing date of October 26, 2012, and an archive date of November 26, 2012, meaning it is no longer open for applications. The full announcement was hosted on the NIH grants site under the provided link, and NIH’s Office of Extramural Research (OER) webmaster contact was listed for technical issues accessing the announcement.
FAQs: Limited Pilot for NIGMS Legacy Community-Wide Scientific Resources (R24) (PAR-10-261)
What is this funding opportunity?
The Limited Pilot for NIGMS Legacy Community-Wide Scientific Resources (R24) was a discretionary NIH funding announcement issued by the National Institute of General Medical Sciences (NIGMS). Its purpose was to provide limited, transitional support to keep certain high-value, community-serving scientific resources operating after their original NIGMS initiatives ended or after a resource award reached a non-renewable endpoint set by the original program.
What was the main goal of the pilot?
The central idea was continuity. NIGMS aimed to prevent the sudden loss of important legacy resources that the broader research community relied on, especially when the original funding mechanism was no longer available.
What does NIGMS mean by a “resource†in this announcement?
In this opportunity, a “resource†was defined as a non-hypothesis-driven activity that provides broadly useful data, materials, tools, or services. The intent was to support shared scientific infrastructure that helps many investigators work faster, improve quality, and reduce costs, rather than advance a single project’s specific hypothesis.
Did the resource need to be broadly accessible?
Yes. A key expectation was broad accessibility to all investigators for clearly defined and well-understood purposes. The resource could not be effectively restricted to a small group or used primarily to support a single lab’s research agenda.
Was this opportunity meant to create new resources?
No. This pilot was strictly for continued support of existing legacy resources that had already been developed through prior NIGMS-supported activities. It was not intended to launch new resources.
What kinds of resources were NIGMS trying to preserve?
The pilot targeted “legacy†resources with demonstrated or strongly evidenced value to a broad research community, particularly those that aligned with the NIGMS mission and directly benefited research communities already supported through the NIGMS grant portfolio.
What types of activities were within scope for funding?
The allowable scope was maintenance-focused rather than research-focused. Examples of supported activities included operating and maintaining the resource through functions such as ongoing curation, distribution, user support, routine updates, infrastructure upkeep, and other sustaining functions.
What activities were considered out of scope?
Hypothesis-driven research activities and major new development efforts were not the focus of this pilot. The program framed the resource as shared infrastructure to be kept functional and available, not as a vehicle for funding new experiments or exploratory science.
Could NIGMS provide partial support?
Yes. NIGMS indicated it would consider funding, including partial support, for qualifying resources.
What kinds of resources would NIGMS not support under this pilot?
NIGMS set boundaries indicating it would consider support only for resources that were not supportable through other NIH institute or center initiatives and that were not yet self-sustaining, commercializable, or otherwise able to operate without federal support.
Why was the opportunity described as “limited†and “transitional�
It was a pilot designed to bridge a gap after original initiatives ended or awards reached non-renewable endpoints. NIGMS cautioned that, because it was a pilot, funding might not extend beyond the stated project period, so applicants needed to plan for the possibility that federal support could end after the award period.
What grant mechanism was used?
The funding mechanism was the NIH R24 grant mechanism, which is commonly used for resource-related projects and other specialized, community-benefiting activities.
Did the announcement specify a set-aside budget or guaranteed number of awards?
No. The announcement did not specify a fixed set-aside budget or a guaranteed number of awards.
What factors affected the number of awards and total funding?
NIGMS stated that the total amount awarded and the number of awards would depend on the number of applications submitted, the scientific and programmatic quality of the applications, the requested duration, and the proposed costs.
Was cost sharing or matching required?
No. Cost sharing or matching was not required.
Who was eligible to apply?
Eligibility was broad and included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. The eligibility language also referenced additional categories in the full announcement and explicitly included eligible federal government agencies and non-U.S. (foreign) organizations.
Was this opportunity limited to U.S. organizations?
No. The eligibility language explicitly noted that non-U.S. (foreign) organizations were eligible applicants.
What was the funding activity category and CFDA number?
The funding activity category was health. The associated CFDA number listed was 93.859 (Biomedical Research and Research Training).
When was the opportunity posted, and what were the closing dates?
The opportunity was posted on August 16, 2010. The original and final closing date was October 26, 2012. The archive date was November 26, 2012.
Is this funding opportunity still open?
No. The opportunity is archived and is no longer open for applications.
Where was the full announcement hosted?
The full announcement was hosted on the NIH grants website under the Funding Opportunity Number PAR-10-261.
Who was listed for technical issues accessing the announcement?
NIH’s Office of Extramural Research (OER) webmaster contact was listed for technical issues related to accessing the announcement.
What does it mean that this was a “discretionary†NIH funding announcement?
The announcement was described as discretionary, meaning it was an NIGMS-issued pilot option intended for a specific transitional purpose: continuing certain legacy, community-serving resources when the original program structure or renewal pathway was no longer available.
What is meant by a “non-renewable endpoint†for a resource award?
The announcement described situations where an original program had a fixed duration and could not be extended under the same terms. This pilot was designed to help keep qualifying resources running beyond those non-renewable endpoints.
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