Opportunity Information: Apply for PAR 16 336
Apply for PAR 16 336
- The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Linking the Provider Recommendation to Adolescent HPV Vaccine Uptake (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.395,.
- This funding opportunity was created on Jun 16, 2016 and posted on Jun 16, 2016.
- Applicants must submit their applications by Jul 16, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Linking the Provider Recommendation to Adolescent HPV Vaccine Uptake (R21) (PAR-16-336) is a discretionary NIH grant opportunity focused on understanding why a clinician's recommendation for the adolescent HPV vaccine sometimes leads to vaccination and sometimes does not. The core idea is that the provider recommendation is one of the strongest drivers of HPV vaccination, but its real-world impact depends heavily on how healthcare is organized and delivered. This FOA invites research that looks beyond individual attitudes and instead examines how the healthcare delivery system can either strengthen or weaken the effectiveness of the recommendation at the point of care.
The opportunity centers on the full pathway from recommendation to uptake, including whether clinicians actually make a recommendation, how that recommendation is communicated, and what happens afterward (for example, whether vaccination occurs during the same visit, whether follow-up is supported, or whether logistical barriers cause drop-off). The FOA highlights that multiple layers influence outcomes: provider characteristics (such as knowledge, confidence, communication style, time constraints, and competing clinical priorities), parent and patient characteristics (such as beliefs about vaccines, perceived risk, trust, health literacy, and readiness to vaccinate), and clinical setting factors (such as workflow, staffing, reminder/recall systems, standing orders, electronic health record prompts, vaccine availability, scheduling practices, and the culture and policies of a clinic or health system). Projects are expected to clarify how these elements interact and to identify leverage points where changes in delivery processes could produce measurable improvements in HPV vaccination.
Because HPV vaccination is a cancer prevention strategy, the FOA explicitly calls for cross-cutting expertise that can connect cancer prevention goals with behavioral science and implementation in clinical environments. Competitive projects would typically draw on skills in immunization promotion, adolescent and parent decision-making, provider communication, and health services or healthcare delivery research. The announcement is geared toward studies that can illuminate mechanisms and practical strategies, such as identifying which recommendation approaches work best in which settings, what system supports make a recommendation more actionable, and what barriers prevent follow-through even after a recommendation is made.
This FOA uses the NIH R21 mechanism, which is designed for exploratory and developmental research. The listed award ceiling is $200,000, supporting projects that generate early evidence, test novel approaches, or build a foundation for larger follow-on studies. The sponsoring agency is within the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH11). It is categorized under Education and Health, with CFDA numbers 93.393 and 93.395.
Eligibility is broad and includes many types of organizations that could realistically conduct this kind of research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education where specified); for-profit organizations other than small businesses; and small businesses, with an additional category for other eligible entities as clarified in the full announcement.
Key dates in the source information show the FOA was posted and created on June 16, 2016, with a closing date of July 16, 2019 (original and current closing dates are the same in the provided record). Overall, the grant opportunity is aimed at producing actionable knowledge about how to make provider recommendations translate more reliably into HPV vaccination, with particular attention to system-level and practice-level factors that can be modified to improve adolescent vaccine uptake.
FAQs: Linking the Provider Recommendation to Adolescent HPV Vaccine Uptake (R21) (PAR-16-336)
What is the focus of this NIH funding opportunity?
This discretionary NIH grant opportunity focuses on understanding why a clinician's recommendation for the adolescent HPV vaccine sometimes results in vaccination and sometimes does not. The emphasis is on the real-world conditions that determine whether a recommendation translates into vaccine uptake.
What is the core idea behind the FOA?
The FOA is built on the idea that a provider recommendation is one of the strongest drivers of HPV vaccination, but its impact depends heavily on how healthcare is organized and delivered. Studies are expected to look beyond individual attitudes and examine healthcare delivery system factors that strengthen or weaken the recommendation at the point of care.
What part of the vaccination process does the FOA want researchers to examine?
The FOA centers on the full pathway from recommendation to uptake. This includes whether clinicians actually make a recommendation, how the recommendation is communicated, and what happens afterward, such as whether vaccination occurs during the same visit, whether follow-up is supported, or whether logistical barriers cause patients to drop off before vaccination occurs.
Does this opportunity focus only on individual beliefs and attitudes?
No. The FOA explicitly encourages research that looks beyond individual attitudes and instead examines how healthcare delivery systems and clinical processes influence whether a provider recommendation leads to vaccination.
What types of factors are highlighted as influencing whether a recommendation leads to vaccination?
The FOA highlights multiple layers of influence, including provider characteristics, parent and patient characteristics, and clinical setting factors. Projects are expected to clarify how these elements interact and identify leverage points where delivery process changes could improve vaccination rates.
What provider characteristics does the FOA mention as important?
Examples include provider knowledge, confidence, communication style, time constraints, and competing clinical priorities.
What parent and patient characteristics does the FOA mention as relevant?
Examples include beliefs about vaccines, perceived risk, trust, health literacy, and readiness to vaccinate.
What clinical setting or system factors does the FOA mention?
Examples include workflow, staffing, reminder/recall systems, standing orders, electronic health record prompts, vaccine availability, scheduling practices, and the culture and policies of a clinic or health system.
What kinds of outcomes or gaps is this FOA trying to address after a recommendation is made?
The FOA points to the possibility of drop-off even after a recommendation occurs, such as when vaccination does not happen during the same visit, follow-up is not supported, or logistical barriers prevent completion.
What is meant by identifying "leverage points" in this FOA?
It refers to pinpointing modifiable parts of healthcare delivery and practice operations (for example, workflows or system supports) where changes could measurably increase the likelihood that a recommendation results in vaccination.
Why does the FOA emphasize system-level and practice-level factors?
Because the FOA is focused on understanding how healthcare delivery can either strengthen or weaken the effectiveness of provider recommendations at the point of care, and how delivery processes can be modified to improve adolescent HPV vaccine uptake.
What types of research themes would be considered responsive based on the description provided?
Based on the provided information, responsive studies would typically examine mechanisms and practical strategies such as: which recommendation approaches work best in which settings; what system supports make a recommendation more actionable; and what barriers prevent follow-through even after a recommendation is made.
How is HPV vaccination framed in this opportunity?
HPV vaccination is framed as a cancer prevention strategy, and the FOA explicitly calls for expertise that connects cancer prevention goals with behavioral science and implementation in clinical environments.
What types of expertise are suggested as important for competitive projects?
The FOA indicates that competitive projects would typically draw on cross-cutting skills in immunization promotion, adolescent and parent decision-making, provider communication, and health services or healthcare delivery research.
What NIH activity code or grant mechanism is used?
This FOA uses the NIH R21 mechanism, which is designed for exploratory and developmental research.
What does the R21 mechanism imply about the type of work expected?
It implies the projects are intended to generate early evidence, test novel approaches, or build a foundation for larger follow-on studies, consistent with exploratory and developmental research.
What is the listed award ceiling for this opportunity?
The listed award ceiling is $200,000.
Which federal department and agency sponsor this FOA?
The sponsoring agency is within the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH11).
How is this grant opportunity categorized?
It is categorized under Education and Health.
What CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.393 and 93.395.
Who is eligible to apply for this grant opportunity?
Eligibility is broad and includes: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education where specified); for-profit organizations other than small businesses; small businesses; and other eligible entities as clarified in the full announcement.
Are government entities eligible to apply?
Yes. The FOA lists multiple government applicants as eligible, including state, county, city or township governments, and special district governments.
Are schools and higher education institutions eligible to apply?
Yes. The FOA includes independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education.
Are tribal governments and tribal organizations eligible?
Yes. The FOA includes federally recognized Native American tribal governments and other tribal organizations.
Are nonprofits eligible to apply?
Yes. The FOA includes nonprofit organizations with or without 501(c)(3) status, with an exclusion noted in the provided text (excluding institutions of higher education where specified).
Are for-profit organizations eligible to apply?
Yes. The FOA includes for-profit organizations other than small businesses, and it separately includes small businesses.
When was this FOA posted and created?
The source information indicates it was posted and created on June 16, 2016.
What is the closing date for this opportunity in the provided record?
The closing date listed is July 16, 2019, and the provided record indicates the original and current closing dates are the same.
What is the overall goal of this funding opportunity?
The overall goal is to produce actionable knowledge about how to make provider recommendations translate more reliably into HPV vaccination, with particular attention to system-level and practice-level factors that can be modified to improve adolescent vaccine uptake.
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