Opportunity Information: Apply for RFA IP 10 006

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Long Term Outcomes of Infants Identified with Congenital CMV Infection (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
  • This funding opportunity was created on Mar 3, 2010 and posted on Mar 3, 2010.
  • Applicants must submit their applications by May 3, 2010 Letter of Intent Receipt Date April 1, 2010 Application Submission Receipt Date May 3, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $550,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $550,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible Institutions You may submit an application(s) if your organization has any of the following characteristics Public nonprofit organizations Private nonprofit organizations Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a PDF file and attach as Other Documents and label as appropriate.
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Opportunity Summary:

The grant opportunity titled "Long Term Outcomes of Infants Identified with Congenital CMV Infection (U01)" (Funding Opportunity Number RFA IP 10 006) was a Centers for Disease Control and Prevention (CDC) discretionary research solicitation using a cooperative agreement mechanism (U01). Its core goal was to support a study that carefully documents and compares long-term health and developmental outcomes in children based on congenital cytomegalovirus (CMV) status at birth. Specifically, the project was intended to describe differences over time in hearing (audiologic outcomes), vision, overall development, cognition, motor function, and physical growth (somatic/growth outcomes) among three groups of children: (1) infants born with symptomatic congenital CMV infection, (2) infants born with congenital CMV infection that appeared asymptomatic at birth, and (3) infants who were uninfected with CMV at birth. In practical terms, the CDC was looking for research that could clarify how outcomes diverge across these groups as children age, helping to define the true long-term burden of congenital CMV and the extent to which children who look healthy at birth may still experience later-onset effects.

This opportunity was categorized under the Health activity area and was tied to CFDA number 93.283 (CDC Investigations and Technical Assistance). The CDC anticipated making one award, with an estimated total funding amount of $550,000 and an award ceiling of $550,000 (no award floor was specified). There was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible or competitive.

Eligibility was broad and designed to accommodate a wide range of organizations capable of carrying out long-term pediatric follow-up research. Eligible applicants included public and private nonprofit organizations, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, Urban Indian health organizations, Tribal Epidemiology Centers, and state and local governments (including U.S. territories and affiliated jurisdictions). The announcement also allowed applications from bona fide agents of states or local governments, but required a formal letter documenting that status, attached to the application materials.

In terms of timing, the funding announcement was posted on March 3, 2010, with an optional or requested Letter of Intent due April 1, 2010, and the full application due May 3, 2010. The opportunity closed on May 3, 2010 and was archived on June 2, 2010. For administrative or access issues related to the full announcement, the listed point of contact was the CDC Procurement and Grants Office (TIMS) reachable by phone at 770-488-2700 or by email at PGOTIM@cdc.gov.

Overall, the opportunity centered on generating high-quality, long-term comparative evidence about how congenital CMV affects children across multiple domains that matter for lifelong functioning. By structuring the research around symptomatic cases, asymptomatic-at-birth infections, and uninfected children, the CDC aimed to support clearer distinctions in prognosis and to strengthen the evidence base for clinical monitoring, early identification of late-emerging effects (especially hearing loss), and broader public health understanding of congenital CMV outcomes.

FAQs: Long Term Outcomes of Infants Identified with Congenital CMV Infection (U01)

What is the title of this grant opportunity?

The opportunity is titled "Long Term Outcomes of Infants Identified with Congenital CMV Infection (U01)."

What is the Funding Opportunity Number?

The Funding Opportunity Number is RFA IP 10 006.

Which federal agency offered this opportunity?

This was a discretionary research solicitation from the Centers for Disease Control and Prevention (CDC).

What type of funding mechanism was used?

The mechanism was a cooperative agreement (U01).

What was the main goal of the funded project?

The core goal was to support a study that documents and compares long-term health and developmental outcomes in children based on congenital cytomegalovirus (CMV) status at birth.

What long-term outcomes was the study expected to examine?

The project was intended to describe differences over time in hearing (audiologic outcomes), vision, overall development, cognition, motor function, and physical growth (somatic/growth outcomes).

How were children grouped for comparison in the proposed research?

The study was designed to compare outcomes among three groups: (1) infants born with symptomatic congenital CMV infection, (2) infants born with congenital CMV infection that appeared asymptomatic at birth, and (3) infants who were uninfected with CMV at birth.

Why did the CDC include both symptomatic and asymptomatic congenital CMV groups?

The aim was to clarify how outcomes diverge across groups as children age and to better understand the long-term burden of congenital CMV, including later-onset effects in children who appeared healthy at birth.

What activity area did this opportunity fall under?

The opportunity was categorized under the Health activity area.

What CFDA number was associated with this funding?

This opportunity was tied to CFDA 93.283 (CDC Investigations and Technical Assistance).

How many awards did the CDC anticipate making?

The CDC anticipated making one award.

What was the estimated total funding amount?

The estimated total funding amount was $550,000.

What was the award ceiling?

The award ceiling was $550,000.

Was there an award floor?

No award floor was specified.

Was cost sharing or matching required?

No. There was no cost sharing or matching requirement, so applicants were not required to contribute non-federal funds.

Who was eligible to apply?

Eligibility was broad and included public and private nonprofit organizations, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, Urban Indian health organizations, Tribal Epidemiology Centers, and state and local governments (including U.S. territories and affiliated jurisdictions).

Could state or local government agents apply?

Yes. The announcement allowed applications from bona fide agents of states or local governments, but required a formal letter documenting that status to be attached to the application materials.

When was the funding announcement posted?

The announcement was posted on March 3, 2010.

Was a Letter of Intent required?

A Letter of Intent was listed as optional or requested, with a due date of April 1, 2010.

When was the full application due?

The full application was due May 3, 2010.

When did the opportunity close?

The opportunity closed on May 3, 2010.

When was the opportunity archived?

The opportunity was archived on June 2, 2010.

Who was the point of contact for administrative or access issues?

The listed point of contact was the CDC Procurement and Grants Office (TIMS).

How could applicants contact the CDC Procurement and Grants Office (TIMS)?

They could be reached by phone at 770-488-2700 or by email at PGOTIM@cdc.gov.

What broader public health purpose did the CDC describe for this research?

The opportunity emphasized strengthening the evidence base for clinical monitoring, early identification of late-emerging effects (especially hearing loss), and broader public health understanding of congenital CMV outcomes.

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