Opportunity Information: Apply for RFA GM 16 003
Apply for RFA GM 16 003
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Maximizing Investigators Research Award for New and Early Stage Investigators (R35)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jun 3, 2015 and posted on Jun 3, 2015.
- Applicants must submit their applications by Nov 19, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $26,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 70 candidate(s).
- Eligible applicants include: Small businesses State governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses County governments Private institutions of higher education Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. See more at http://grants.nih.gov/grants/guide/rfa files/RFA GM 16 003.html#sthash.7YotyQke.dpuf
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Opportunity Summary:
The Maximizing Investigators Research Award for New and Early Stage Investigators (MIRA, R35) is a discretionary National Institutes of Health (NIH) grant program designed to support the overall research program of an individual investigator, rather than a single tightly defined project. In practical terms, the award is meant to fund the body of work conducted in an investigator's laboratory as long as that work fits within the mission of the National Institute of General Medical Sciences (NIGMS). This structure is intended to give investigators more stability and flexibility to pursue important scientific questions, adapt to new findings, and sustain productive research momentum without having to divide their efforts across multiple separate project-specific applications.
This opportunity was issued under Funding Opportunity Number RFA-GM-16-003, titled "Maximizing Investigators Research Award for New and Early Stage Investigators (R35)." It falls under the "Health" funding activity category and uses the standard NIH "Grant" funding instrument. NIH anticipated making approximately 70 awards, supported by an estimated total program funding level of about $26,000,000. The listed award ceiling is $250,000, which signals an upper bound on the expected budget level for individual awards under this announcement.
The program does not require cost sharing or matching, which means applicants are not expected to contribute non-federal funds as a condition of receiving the award. The CFDA listing associated with the opportunity is 93.859, "Biomedical Research and Research Training," reflecting its alignment with federal biomedical research support and workforce development goals.
Eligibility is broad across many U.S.-based organization types. Eligible applicant organizations include public and private institutions of higher education, state and local governments (including county, city/township, special district, and independent school districts), nonprofit organizations (both 501(c)(3) and certain non-501(c)(3) nonprofits), public housing authorities/Indian housing authorities, for-profit organizations (including small businesses and other for-profits), and Native American tribal governments and organizations, including federally recognized tribal governments. The announcement also explicitly identifies a range of institution types and community-anchored organizations as eligible, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American and Native American Pacific Islander-serving institutions (AANAPISIs), as well as faith-based or community-based organizations and certain eligible federal agencies.
While organizational eligibility is broad, the geographic eligibility rules are stricter. Non-U.S. entities (foreign institutions) are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply. However, the announcement indicates that "foreign components" are allowable as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may be able to include certain discrete international collaborations or elements if they meet NIH's definition and requirements for a foreign component.
The timeline information included in the source indicates the opportunity was posted on June 3, 2015, with an original and current closing date of November 19, 2015, and an archive date of December 20, 2015. In other words, this specific funding announcement is historical and was open during that 2015 cycle, though the broader MIRA concept and related NIH/NIGMS funding mechanisms may continue under other, newer announcements.
For applicants or interested parties seeking the official full details, the announcement provides an NIH Grants Guide link to the full text of RFA-GM-16-003. Contact support is routed through the NIH Office of Extramural Research (OER) webmaster for technical issues accessing or linking to the announcement (FBOWebmaster@OD.NIH.GOV).
Maximizing Investigators Research Award for New and Early Stage Investigators (MIRA, R35) - FAQs (RFA-GM-16-003)
1) What is the Maximizing Investigators Research Award (MIRA, R35) for New and Early Stage Investigators?
MIRA (R35) is a discretionary National Institutes of Health (NIH) grant program that supports the overall research program of an individual investigator, rather than a single narrowly defined project. The intent is to fund the body of work conducted in an investigator's laboratory, as long as it aligns with the mission of the National Institute of General Medical Sciences (NIGMS).
2) How is this award different from a typical project-based research grant?
Instead of requiring applicants to propose one tightly scoped project, this award supports an investigator's broader research direction. The structure is designed to provide stability and flexibility so investigators can pursue important scientific questions, adapt to new findings, and maintain research momentum without splitting efforts across multiple project-specific applications.
3) What is the Funding Opportunity Number (FON) and official title?
The Funding Opportunity Number is RFA-GM-16-003. The title is "Maximizing Investigators Research Award for New and Early Stage Investigators (R35)."
4) Which NIH institute is associated with the mission alignment for this program?
The supported research program must fit within the mission of the National Institute of General Medical Sciences (NIGMS).
5) What funding activity category and funding instrument does this opportunity use?
The funding activity category is Health, and the funding instrument is an NIH Grant.
6) How many awards were anticipated under this announcement?
NIH anticipated making approximately 70 awards under this funding opportunity.
7) What was the estimated total program funding level for this opportunity?
The estimated total program funding level was approximately $26,000,000.
8) What is the award ceiling listed for individual awards?
The listed award ceiling is $250,000, indicating an upper bound on the expected budget level for an individual award under this announcement.
9) Is cost sharing or matching required?
No. This opportunity does not require cost sharing or matching, so applicants are not expected to contribute non-federal funds as a condition of receiving the award.
10) What CFDA number is associated with this opportunity?
The CFDA listing associated with this opportunity is 93.859, titled "Biomedical Research and Research Training."
11) What types of U.S. organizations are eligible to apply?
Eligible applicant organizations include a wide range of U.S.-based entities, including:
- Public and private institutions of higher education
- State governments and local governments (including county, city/township, special district, and independent school districts)
- Nonprofit organizations (both 501(c)(3) and certain non-501(c)(3) nonprofits)
- Public housing authorities / Indian housing authorities
- For-profit organizations (including small businesses and other for-profits)
- Native American tribal governments and organizations, including federally recognized tribal governments
- Certain eligible federal agencies
- Faith-based or community-based organizations
12) Are minority-serving institutions specifically identified as eligible?
Yes. The announcement explicitly identifies a range of institution types as eligible, including:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving Institutions
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian-serving institutions
- Asian American and Native American Pacific Islander-serving institutions (AANAPISIs)
13) Are foreign (non-U.S.) organizations eligible to apply directly?
No. Non-U.S. entities (foreign institutions) are not eligible to apply under this announcement.
14) Are non-U.S. components of U.S. organizations eligible to apply?
No. The announcement states that non-U.S. components of U.S. organizations are not eligible to apply.
15) Are "foreign components" allowed at all?
Yes. While foreign institutions cannot apply directly, the announcement indicates that "foreign components" are allowable as defined in the NIH Grants Policy Statement. This suggests a U.S. applicant may be able to include certain discrete international collaborations or elements if they meet NIH's definition and requirements for a foreign component.
16) When was this opportunity posted, and what were the closing and archive dates?
The opportunity was posted on June 3, 2015. The original and current closing date listed is November 19, 2015. The archive date is December 20, 2015.
17) Is this specific funding announcement still open?
No. Based on the provided dates (closing in November 2015 and archived in December 2015), this specific funding announcement (RFA-GM-16-003) is historical and was open during the 2015 cycle.
18) Where can applicants find the official full details for RFA-GM-16-003?
The announcement provides an NIH Grants Guide link to the full text of RFA-GM-16-003 for official requirements and details.
19) Who should be contacted for technical issues accessing or linking to the announcement?
Technical support is routed through the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
20) What is the main purpose of the MIRA structure for investigators?
The stated purpose is to provide more stability and flexibility for investigators so they can pursue important scientific questions, adapt to new findings, and sustain productive research momentum without needing to divide efforts among multiple separate, project-specific applications.
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