Opportunity Information: Apply for RFA GM 17 002

  • The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Maximizing Investigator's Research Award (R35)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859,.
  • This funding opportunity was created on Mar 09, 2016 and posted on Mar 09, 2016.
  • Applicants must submit their applications by May 20, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 100 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA GM 17 002

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Opportunity Summary:

The Maximizing Investigator's Research Award (MIRA), also known as the R35 mechanism, is a discretionary federal grant opportunity offered by the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services, specifically associated with NIGMS (the National Institute of General Medical Sciences). The main purpose of this program is to support the full body of work happening in an investigator's laboratory, as long as that work fits within the scientific mission of NIGMS. Instead of funding a single narrowly defined project, MIRA is designed to provide broader, more flexible support that can cover the range of related research activities pursued by an investigator and their lab, giving them room to follow promising directions as they emerge.

This opportunity is listed under Funding Opportunity Number RFA-GM-17-002 and falls under the "Grant" funding instrument type, with the activity category classified as Health. The program is connected to CFDA numbers 93.859, which identifies the federal assistance area tied to the grant. The opportunity was created and posted on March 9, 2016, and the application closing date was May 20, 2016 (with the original and current closing dates matching, indicating no extension in the provided record).

In terms of expected funding scale, the opportunity lists an award ceiling of $750,000 and anticipates making about 100 awards. While the ceiling indicates the maximum amount that may be awarded under this announcement, actual award sizes can vary depending on programmatic decisions, applicant scope, and budget justification, but the listing makes clear that awards can reach up to that upper limit. The relatively high expected number of awards suggests a substantial program intended to support many investigators rather than a small handful of large, specialized projects.

Eligibility is broad and includes many types of applicants across government, education, nonprofit, and private sectors. Eligible entities include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education in those specific nonprofit categories); for-profit organizations other than small businesses; small businesses; and additional categories referenced as "Others" with further clarification typically found in the full eligibility text of the announcement. This wide eligibility range signals that the program is not restricted only to universities, even though research awards of this type are most commonly associated with academic and research institutions.

Overall, MIRA (R35) is positioned as a lab-centered support mechanism aimed at maximizing the productivity and stability of an investigator's research program within the NIGMS mission space. The key distinguishing feature in the description is that it supports "all of the research in an investigator's laboratory" that aligns with NIGMS, emphasizing flexibility and program-level support rather than single-project funding.

Maximizing Investigator's Research Award (MIRA / R35) - FAQ

What is the Maximizing Investigator's Research Award (MIRA)?

The Maximizing Investigator's Research Award (MIRA), also known as the R35 mechanism, is a discretionary federal grant opportunity offered by the National Institutes of Health (NIH), within the U.S. Department of Health and Human Services. It is specifically associated with the National Institute of General Medical Sciences (NIGMS).

What is the main purpose of the MIRA (R35) program?

The main purpose of MIRA is to support the full body of work occurring in an investigator's laboratory, as long as that work fits within the scientific mission of NIGMS. The intent is to provide broader, more flexible support than a single narrowly defined project grant.

How is MIRA different from a typical single-project research grant?

Instead of funding one narrowly scoped project, MIRA is designed to provide lab-centered support that can cover a range of related research activities pursued by an investigator and their lab. This structure is meant to give investigators room to follow promising research directions as they emerge, as long as the work aligns with the NIGMS mission.

Which federal agency and institute are associated with this opportunity?

This opportunity is offered through the National Institutes of Health (NIH) and is specifically associated with NIGMS (the National Institute of General Medical Sciences).

What is the Funding Opportunity Number for this MIRA announcement?

The Funding Opportunity Number listed is RFA-GM-17-002.

What type of funding instrument is this opportunity?

The listing identifies the funding instrument type as a Grant.

What activity category is this opportunity classified under?

The activity category is classified as Health.

What CFDA number is associated with this opportunity?

The opportunity is connected to CFDA number 93.859.

When was this opportunity created and posted?

The opportunity record states it was created and posted on March 9, 2016.

What was the application closing date?

The application closing date listed is May 20, 2016. The record indicates the original and current closing dates match, suggesting no extension in the provided information.

Was the application deadline extended?

Based on the provided record, no extension is indicated because the original and current closing dates are the same (May 20, 2016).

What is the maximum award amount (award ceiling) listed for this opportunity?

The listing shows an award ceiling of $750,000.

Does the award ceiling mean every award will be $750,000?

No. The ceiling represents the maximum amount that may be awarded under this announcement. The listing notes that actual award sizes can vary depending on programmatic decisions, the scope described by the applicant, and the budget justification.

How many awards does NIH/NIGMS expect to make under this opportunity?

The opportunity anticipates making about 100 awards.

What does the expected number of awards suggest about the program?

The relatively high expected number of awards (about 100) suggests a substantial program designed to support many investigators, rather than a small number of large, specialized projects.

Who is eligible to apply for this MIRA (R35) opportunity?

Eligibility is described as broad and includes many types of applicants across government, education, nonprofit, and private sectors. The eligible categories listed include state governments; county governments; city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with 501(c)(3) status (excluding institutions of higher education within that nonprofit category as described); nonprofit organizations without 501(c)(3) status (excluding institutions of higher education within that nonprofit category as described); for-profit organizations other than small businesses; small businesses; and additional categories referenced as "Others" (with further clarification typically found in the full eligibility text of the announcement).

Are universities and colleges eligible applicants?

Yes. The listing explicitly includes public and state-controlled institutions of higher education and private institutions of higher education as eligible applicants.

Are nonprofit organizations eligible to apply?

Yes. The eligibility list includes nonprofit organizations with and without 501(c)(3) status, with the caveat in the provided text that certain nonprofit categories are described as "not institutions of higher education" within those specific nonprofit classifications.

Are for-profit organizations eligible to apply?

Yes. The listing includes for-profit organizations other than small businesses, as well as small businesses, as eligible applicants.

Are government entities eligible to apply?

Yes. Eligible entities include state, county, city/township, and special district governments, as well as independent school districts and public housing authorities/Indian housing authorities.

Are tribal governments and tribal organizations eligible?

Yes. The listing includes federally recognized Native American tribal governments and other tribal organizations among eligible applicants.

Does this program only fund research at universities?

No. While research awards like this are often associated with academic and research institutions, the eligibility described in the listing is broad and not limited to universities.

What kinds of research does MIRA support?

MIRA supports the full body of research happening in an investigator's laboratory, as long as the work fits within the scientific mission of NIGMS.

Does MIRA fund a single project or a broader research program?

Based on the description provided, MIRA is intended to support a broader research program within an investigator's lab, rather than a single narrowly defined project.

What is the key distinguishing feature of MIRA described in the listing?

The key distinguishing feature is that it supports "all of the research in an investigator's laboratory" that aligns with NIGMS, emphasizing flexibility and program-level support rather than single-project funding.

Is MIRA described as a discretionary grant opportunity?

Yes. The listing describes MIRA (R35) as a discretionary federal grant opportunity.

Where does this opportunity sit within the federal government?

This opportunity is offered by NIH, which is part of the U.S. Department of Health and Human Services, and it is specifically associated with NIGMS.

Browse more opportunities from the same agency: HHS-NIH11

Browse more opportunities from the same category: Health

Next opportunity: NIH Director's Early Independence Awards (DP5)

Previous opportunity: Institute of Education Sciences (IES): Research Training Programs in Special Education CFDA Number 84.324B

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