MBRS Research Initiative for Scientific Enhancement (RISE) (R25) | Apply Online

Opportunity Summary:

The MBRS Research Initiative for Scientific Enhancement (RISE) (R25) is a National Institutes of Health (NIH) institutional training and research education grant designed to increase the number of people from groups underrepresented in biomedical and behavioral research who successfully progress to and complete Ph.D. degrees. It sits within the broader Minority Biomedical Research Support (MBRS) program, which was created in response to a legislative mandate to expand participation in biomedical and behavioral research by underrepresented minority faculty, investigators, and students. In practical terms, RISE funds institutions to build or strengthen structured, well-integrated development programs that improve students preparation, research skills, and academic competitiveness as they move through the pipeline toward doctoral-level research careers.

This opportunity is a discretionary grant program in the health funding activity area (CFDA 93.859, Biomedical Research and Research Training) and does not require cost sharing or matching. The total estimated funding noted in the announcement is $6,000,000. Rather than supporting an individual applicant directly, RISE supports an institutional program, meaning the award is made to an eligible organization that then implements a coordinated set of activities and supports for its student participants. The expectation is that these activities are not piecemeal or informal, but intentionally designed, developmentally sequenced, and integrated into a coherent plan that strengthens research training, mentoring, and professional development leading toward Ph.D. completion.

Eligible applicants include a wide range of U.S.-based entities, particularly institutions of higher education (both public/state-controlled and private), as well as certain governmental organizations such as independent school districts, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, and Native American tribal governments and tribal organizations (including both federally recognized tribal governments and other tribal organizations). Foreign institutions are explicitly not eligible to apply. The listing also indicates there may be additional nuances in eligibility in the full announcement, so applicants typically need to confirm institutional fit by reviewing NIH program guidance and the detailed eligibility text.

There are several notable application requirements and constraints that shape how an institution must apply. Applications must include a plan for Training in the Responsible Conduct of Research, which is a standard NIH expectation for training-oriented mechanisms and is explicitly called out as required here. In addition, every application must contain an evaluation plan, reflecting NIH emphasis on measurable outcomes and continuous improvement for institutional training programs. The notice warns that applications missing these required sections may be delayed in review or may not be reviewed at all, so they function as gating components rather than optional enhancements.

The program also limits duplication and overlap by restricting how many applications and awards an institution can have at one time. An applicant institution may not submit, or have pending, more than one RISE grant application, and eligible institutions may hold only one RISE award. That makes internal coordination important, since institutions typically need to decide on a single unified approach rather than submitting multiple versions from different departments or campuses under the same eligible entity.

In terms of timing, the opportunity was posted on September 11, 2006, with multiple receipt dates referenced rather than a single deadline, and it was later archived (archive date November 13, 2009). The closing information indicates multiple receipt dates through October 13, 2009, which means the program was structured around repeated submission cycles during the active period, consistent with many NIH announcements that allow recurring due dates. Because the announcement is archived, it is mainly useful as historical reference unless NIH has reissued a current version under a different number; anyone looking to apply today would need to locate the most recent active FOA for the RISE mechanism or related NIH training programs.

The administering agency is the National Institutes of Health, and the full announcement was provided through the NIH grants guide at the link included in the source data (http://grants.nih.gov/grants/guide/pa-files/PAR-06-548.html). For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).

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