Opportunity Information: Apply for PAR 07 157

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Mechanism for Time Sensitive Research Opportunities (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Dec 16, 2008 and posted on Dec 13, 2006.
  • Applicants must submit their applications by Jun 9, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: County governments City or township governments Public housing authorities/Indian housing authorities State governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education.
  • Foreign institutions are not eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PAR 07 157

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Opportunity Summary:

This grant opportunity, titled Mechanism for Time Sensitive Research Opportunities (R01) (Funding Opportunity Number PAR 07 157), is a National Institutes of Health (NIH) funding announcement led by the National Institute of Mental Health (NIMH) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its central goal is to fund public mental health and substance abuse services research when the window to study an important real-world change is short and would likely close if investigators had to wait through the standard NIH review and award timeline. The program is designed for situations where service systems, financing structures, policies, or other rapidly shifting conditions create a rare chance to collect empirical evidence right as changes unfold, making speed a defining requirement rather than a convenience.

A project is considered appropriate for this FOA only when it meets three core conditions. First, the scientific value and feasibility must be clearly established, meaning the question is strong, the methods are sound, and the study can realistically be executed. Second, the study must require rapid review and rapid funding in order to answer the question and implement the design, because delays would undermine the ability to observe or measure the phenomenon of interest. Third, the knowledge to be gained must be unavailable through the regular NIH submission and review cycle, typically because the event, policy shift, system redesign, or other opportunity would pass before a standard award could be made. In other words, the application has to make the case that this is an uncommon, scientifically significant opportunity that only exists if the project begins with minimal delay.

The funding mechanism used is the NIH Research Project Grant (R01), which generally supports more substantial, hypothesis-driven projects compared with smaller or more developmental NIH awards. This R01 FOA runs alongside parallel announcements with the same scientific scope that use different mechanisms: an R03 for smaller-scale projects and an R34 for clinical exploratory or developmental work. Applicants are expected to select the mechanism that best fits the maturity and size of their proposed research, with this specific announcement aimed at projects that are appropriately sized for an R01.

Funding levels and project durations are not fixed in advance. The NIH notes that the nature and scope of studies will differ widely given the time-sensitive, opportunistic character of the research, so individual award budgets and timelines may vary. Likewise, the number of awards and total dollars ultimately committed depend on the volume of submissions, their quality, proposed duration, and requested costs. There is no cost sharing or matching requirement.

Eligibility is broad across the US research and public service landscape but excludes foreign institutions. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and private institutions of higher education; nonprofit organizations (including those with and without 501(c)(3) status, with the standard caveat excluding non-501(c)(3) entities that are institutions of higher education); for-profit organizations (including small businesses and other for-profits); public housing authorities and Indian housing authorities; and Native American tribal governments and tribal organizations (including federally recognized tribal governments and other tribal entities). The announcement also specifies that eligible federal government agencies may apply, and that faith-based and community-based organizations are eligible as well.

From an administrative standpoint, the opportunity falls under the Health funding activity category, with CFDA listings that include 93.242 (Mental Health Research Grants) and 93.273 (Alcohol Research Programs). The original posting date is December 13, 2006, and the announcement used multiple receipt dates rather than a single deadline, with the then-current closing date listed as June 9, 2009, and an archive date of July 9, 2009. The full announcement was hosted through the NIH grants guide at the provided link, and NIH Office of Extramural Research web support contacts were listed for access or technical issues.

In practical terms, the key takeaway is that this FOA is meant for investigators who can clearly show that a fast-moving policy or system change has created a fleeting but high-value research opportunity in mental health or substance use services, and that only an expedited review and funding path will allow the study to happen in time to produce evidence that would otherwise be lost.

Frequently Asked Questions (FAQs): Mechanism for Time Sensitive Research Opportunities (R01) (PAR 07 157)

What is the title and funding opportunity number for this grant?

The opportunity is titled Mechanism for Time Sensitive Research Opportunities (R01) and the Funding Opportunity Number is PAR 07 157.

Which agencies lead this NIH funding announcement?

This NIH announcement is led by the National Institute of Mental Health (NIMH) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What is the main purpose of this FOA?

The central goal is to fund public mental health and substance abuse services research when an important real-world change is unfolding and the opportunity to study it is time sensitive. The FOA is designed for situations where waiting for the standard NIH review and award timeline would cause the window to collect critical evidence to close.

What kinds of situations is this program meant to address?

This program targets fast-moving, real-world conditions such as changes in service systems, financing structures, policies, or other rapidly shifting circumstances that create a rare opportunity to collect empirical data as the change occurs.

What makes a project appropriate for this FOA?

A project is appropriate only if it meets three core conditions described in the announcement: (1) the scientific value and feasibility are clearly established, (2) the study requires rapid review and rapid funding because delays would undermine the design or the ability to measure the phenomenon, and (3) the knowledge cannot be obtained through the regular NIH submission and review cycle because the opportunity would pass before a standard award could be made.

What does it mean that the opportunity is "time sensitive"?

It means the research question depends on capturing data during a narrow window created by a real-world event or change. If the project cannot start with minimal delay, the key evidence may be lost or the phenomenon may no longer be observable in the same way.

How does this FOA differ from a typical NIH funding timeline?

It is specifically intended for cases where the standard NIH submission, review, and award cycle would be too slow to allow the study to begin in time to capture the time-limited research opportunity.

What grant mechanism does this announcement use?

This FOA uses the NIH Research Project Grant (R01) mechanism.

Why is the R01 mechanism significant here?

The R01 generally supports more substantial, hypothesis-driven research projects compared with smaller or more developmental awards. This particular FOA is intended for projects that are appropriately sized and mature enough for an R01, while still requiring rapid start due to a fleeting research opportunity.

Are there related announcements using other NIH mechanisms?

Yes. The announcement notes parallel FOAs with the same scientific scope that use different mechanisms, including an R03 for smaller-scale projects and an R34 for clinical exploratory or developmental work. Applicants are expected to select the mechanism that best fits the maturity and size of their research.

Are funding amounts and project durations fixed?

No. Funding levels and project durations are not fixed in advance. The NIH notes that the nature and scope of time-sensitive studies can vary widely, so budgets and timelines may differ by project.

Is the number of awards predetermined?

No. The number of awards and the total dollars committed depend on factors such as the number of applications submitted, their scientific quality, proposed duration, and requested costs.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad across U.S. organizations and agencies, including state, county, city or township governments; special district governments; independent school districts; public and private institutions of higher education; nonprofit organizations (including those with and without 501(c)(3) status, with the stated caveat excluding non-501(c)(3) entities that are institutions of higher education); for-profit organizations (including small businesses and other for-profits); public housing authorities and Indian housing authorities; Native American tribal governments and tribal organizations; and eligible federal government agencies. The announcement also states that faith-based and community-based organizations are eligible.

Are foreign institutions eligible to apply?

No. The eligibility description explicitly excludes foreign institutions.

Are faith-based and community-based organizations allowed to apply?

Yes. The FOA specifies that faith-based and community-based organizations are eligible.

Are for-profit organizations eligible?

Yes. The eligibility list includes for-profit organizations, including small businesses and other for-profits.

Are tribal governments and tribal organizations eligible?

Yes. Eligible applicants include Native American tribal governments (federally recognized and other tribal entities) and tribal organizations.

What is the funding activity category for this opportunity?

The announcement falls under the Health funding activity category.

What CFDA numbers are associated with this FOA?

The CFDA listings include 93.242 (Mental Health Research Grants) and 93.273 (Alcohol Research Programs).

When was this announcement originally posted?

The original posting date is listed as December 13, 2006.

Did the FOA have a single deadline or multiple receipt dates?

The announcement used multiple receipt dates rather than a single deadline.

What was the closing date and archive date listed for the announcement?

The then-current closing date is listed as June 9, 2009, and the archive date is listed as July 9, 2009.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guide at the provided link referenced in the opportunity description.

Who should be contacted for access or technical issues related to NIH extramural systems?

The opportunity notes that NIH Office of Extramural Research web support contacts were listed for access or technical issues.

What is the practical takeaway for potential applicants?

This FOA is intended for investigators who can clearly demonstrate that a fast-moving policy or system change has created a fleeting but high-value research opportunity in mental health or substance use services, and that only an expedited review and funding path will allow the study to start in time to produce evidence that would otherwise be lost.

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