Opportunity Information: Apply for PAR 06 249

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Mechanism for Time Sensitive Research Opportunities (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Dec 16, 2008 and posted on Mar 17, 2006.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $50,000.00 in funding.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Private institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses City or township governments State governments County governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply. Faith based or community based organizations are eligible.
Apply for PAR 06 249

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Opportunity Summary:

The NIH funding opportunity "Mechanism for Time Sensitive Research Opportunities (R03)" (Funding Opportunity Number PAR-06-249) was designed to support small, fast-moving research projects in mental health and substance use-related fields where the window to study a real-world change is limited. The core idea is to fund empirical research that must be launched quickly because the underlying conditions are changing in real time, such as shifts in service delivery systems, health care financing, policy reforms, or other rapidly evolving environments that affect mental health, alcohol, and drug services. In practice, this announcement is aimed at researchers who have a well-defined question tied to an urgent, time-limited opportunity, where waiting for a traditional grant cycle would mean missing the chance to collect meaningful data.

This FOA uses the NIH R03 mechanism, which is specifically intended for small research projects that can be completed in a relatively short period with limited resources. The R03 mechanism is not renewable, which reinforces the expectation that proposed studies are targeted, efficient, and focused on producing results quickly rather than building a long, multi-phase program of research under the same award. The announcement also notes that it runs in parallel with other NIH opportunities of the same scientific scope but different grant mechanisms, including an R01 version (PAR-05-150) for larger, traditional research projects and an R34 option (PAR-06-250) for exploratory work in mental health intervention and services research. That parallel structure signals that NIH wanted to support the same general kinds of time-sensitive topics, but at different scales and stages of research development.

The maximum award amount listed is an award ceiling of $50,000, reflecting the small-grant nature of the R03. The FOA emphasizes that the total number of awards and total dollars actually awarded depend on typical NIH factors: how many applications are submitted, the scientific merit and overall quality of those applications, the proposed project duration and budget, and the availability of funds across participating NIH Institutes and Centers. In other words, there is no guaranteed number of awards; funding decisions follow peer review outcomes and institute-level budget priorities.

Eligibility is broad and includes many types of organizations that conduct or support research. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, independent school districts, special district governments, public housing authorities (including Indian housing authorities), city/township, county, and state governments, federally recognized Native American tribal governments, and other Native American tribal organizations. The FOA also allows applications from for-profit organizations other than small businesses. In addition, it explicitly states that foreign institutions may apply, eligible federal agencies may apply, and faith-based or community-based organizations are eligible, which widens the pool beyond the typical university-centered applicant base and reflects the applied, services-oriented nature of the research being solicited.

Administratively, the opportunity is categorized as a discretionary grant in the education and health activity area and is associated with CFDA numbers tied to mental health research (93.242), alcohol research programs (93.273), and drug abuse and addiction research programs (93.279). There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award. The FOA was posted on March 17, 2006, and used multiple receipt dates (rather than a single deadline), with applicants directed to the full announcement for the specific schedule. The archive date is July 10, 2009, indicating that this particular posting is no longer active, though similar time-sensitive mechanisms may exist under newer NIH announcements.

For applicants trying to determine fit, the practical takeaway is that PAR-06-249 was meant for tightly scoped, rapidly executable studies in mental health and substance use services research (and broader alcohol/drug research) where timing is critical. The best-aligned projects would be those that can credibly be completed with modest funding, rely on a clear and immediate natural experiment or system change, and produce actionable findings before the opportunity disappears. The full announcement was hosted by NIH and included additional details on application requirements and deadlines, with technical access support available through the NIH Office of Extramural Research webmaster.

Frequently Asked Questions (FAQs)

What is the "Mechanism for Time Sensitive Research Opportunities (R03)" funding opportunity (PAR-06-249)?

PAR-06-249 is an NIH Funding Opportunity Announcement (FOA) designed to support small, fast-moving empirical research projects in mental health and substance use-related fields. It targets situations where the chance to study an important real-world change is limited because conditions are shifting in real time.

What does "time sensitive" mean in the context of this FOA?

"Time sensitive" refers to research opportunities where the window to collect meaningful data is short, and delaying to fit a traditional grant timeline could mean missing the opportunity altogether. The FOA focuses on projects that must be launched quickly because the underlying environment is changing.

What kinds of real-world changes does this FOA emphasize?

The FOA highlights changes such as shifts in service delivery systems, health care financing changes, policy reforms, and other rapidly evolving environments that affect mental health, alcohol, and drug services.

What research areas are included under this opportunity?

The FOA is focused on mental health and substance use-related fields, including research connected to mental health services, alcohol-related research, and drug abuse/addiction-related research. It is oriented toward applied, services-related questions where timing is critical.

What grant mechanism does this FOA use?

This FOA uses the NIH R03 mechanism, which is intended for small research projects that can be completed in a relatively short period with limited resources.

Is the R03 award under this FOA renewable?

No. The R03 mechanism described here is not renewable, reinforcing the expectation that projects are targeted and designed to produce results quickly rather than support a long, multi-phase research program under the same award.

How is this R03 FOA related to other NIH opportunities?

The FOA runs in parallel with other NIH opportunities that cover similar time-sensitive scientific scope but use different mechanisms. It references an R01 version (PAR-05-150) for larger, traditional projects and an R34 option (PAR-06-250) for exploratory work in mental health intervention and services research.

What is the maximum award amount?

The FOA lists an award ceiling of $50,000, consistent with the small-grant nature of the R03 mechanism.

Is there a guaranteed number of awards?

No. The FOA notes that the total number of awards and total dollars awarded depend on typical NIH factors such as the number of applications received, scientific merit and overall application quality, the proposed project duration and budget, and the availability of funds across participating NIH Institutes and Centers.

What factors influence whether an application is funded?

Based on the FOA description, funding depends on peer review outcomes (scientific merit and quality), how many applications are submitted, the requested budget and project duration, and the availability of funds and priorities within participating NIH Institutes and Centers.

Who is eligible to apply?

Eligibility is broad. The FOA includes public and private institutions of higher education, nonprofits (with and without 501(c)(3) status), independent school districts, special district governments, public housing authorities (including Indian housing authorities), city/township governments, county and state governments, federally recognized Native American tribal governments, and other Native American tribal organizations.

Are for-profit organizations eligible?

Yes. The FOA allows applications from for-profit organizations other than small businesses.

Are foreign institutions eligible to apply?

Yes. The FOA explicitly states that foreign institutions may apply.

Can federal agencies apply?

Yes. The FOA states that eligible federal agencies may apply.

Are faith-based or community-based organizations eligible?

Yes. The FOA explicitly notes that faith-based or community-based organizations are eligible.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.

How is this opportunity categorized administratively?

The FOA is categorized as a discretionary grant in the education and health activity area and is associated with CFDA numbers 93.242 (mental health research), 93.273 (alcohol research programs), and 93.279 (drug abuse and addiction research programs).

When was the FOA posted?

The FOA was posted on March 17, 2006.

Did the FOA have a single deadline?

No. The FOA used multiple receipt dates rather than a single deadline, and applicants were directed to the full announcement for the specific schedule.

Is this FOA still active?

No. The archive date is July 10, 2009, indicating this particular posting is no longer active, even though similar time-sensitive mechanisms may exist under newer NIH announcements.

What types of projects are the best fit for PAR-06-249?

The FOA is best aligned with tightly scoped, rapidly executable studies that can credibly be completed with modest funding, are tied to an immediate and time-limited opportunity (such as a natural experiment or system change), and can produce useful findings before the window to observe the change closes.

What is the main practical reason to use this mechanism instead of a traditional grant cycle?

The FOA is meant for situations where waiting for a traditional grant cycle would likely cause the research team to miss the chance to collect timely, meaningful data about a real-world change.

Where could applicants find additional submission details and support?

The FOA indicates that the full announcement hosted by NIH included additional details on application requirements and deadlines, and that technical access support was available through the NIH Office of Extramural Research webmaster.

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