Opportunity Information: Apply for PA 09 017

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Medical Management of Older Patients with HIV/AIDS (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.361 Nursing Research 93.856 Microbiology and Infectious Diseases Research 93.866 Aging Research.
  • This funding opportunity was created on Dec 14, 2011 and posted on Oct 29, 2008.
  • Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Special district governments County governments Independent school districts Native American tribal governments (Federally recognized) City or township governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Small businesses For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for PA 09 017

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Opportunity Summary:

The Medical Management of Older Patients with HIV/AIDS (R01) funding opportunity (PA-09-017) is an NIH discretionary grant program designed to support research that improves how HIV is diagnosed and medically managed in older adults. The core aim is clinical and translational work focused on the real-world medical issues that arise when people age with HIV, including the consequences of long-term infection and treatment. The announcement is sponsored by several NIH components with overlapping interests in aging, infectious disease, mental health aspects of HIV, and nursing research: the National Institute on Aging (NIA), the National Institute of Allergy and Infectious Diseases (NIAID), the Center for Mental Health Research on AIDS within the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR). Taken together, these sponsors signal an interest in studies that are grounded in patient care, connect clinical observations to mechanisms or interventions, and address complex comorbidities and care delivery challenges common in older populations living with HIV.

The program uses the NIH Research Project Grant (R01) mechanism, which typically supports mature, hypothesis-driven projects with a well-developed research plan and sufficient preliminary data. This FOA is part of a coordinated set of opportunities with the same scientific scope offered under different grant mechanisms, allowing investigators to choose the format that best fits their stage and project size. In parallel, NIH offered PA-09-018 using the R03 (Small Research Grant) mechanism and PA-09-019 using the R21 (Exploratory/Developmental) mechanism. In practical terms, PA-09-017 is the pathway intended for more comprehensive projects that require greater time, resources, and a broader investigative approach than an R03 or many R21s.

The funding level is not guaranteed because awards depend on the availability of appropriated funds and the number of applications that are both submitted and judged highly meritorious through NIH peer review. The listing includes an award ceiling of $500,000, which generally functions as an upper boundary for the opportunity as published, though actual award size and structure would follow NIH policy and institute-specific budget guidance at the time. No cost sharing or matching is required, which lowers barriers for applicants that might otherwise struggle to provide institutional or third-party match.

Eligibility is broad and reflects NIH’s standard approach of supporting strong science across many organizational types. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status (including community-based and faith-based organizations), for-profit organizations (including small businesses and other for-profit entities), and a wide range of government bodies such as state, county, city/township governments, special district governments, independent school districts, and public housing authorities. The announcement also explicitly includes tribal governments and tribal organizations (federally recognized and other than federally recognized), tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities, U.S. territories or possessions, and certain regional organizations. Notably, non-U.S. entities (foreign organizations) are included as eligible applicants, indicating that NIH was open to internationally based expertise and study populations when scientifically justified and compliant with NIH requirements.

Key administrative details anchor the opportunity in time and NIH’s grant system. The FOA was posted on October 29, 2008, with closing dates listed as January 7, 2012 (original) and May 7, 2012 (current at the time of the record), and it was archived on June 7, 2012. The associated CFDA numbers show the participating program areas and funding lines that could be relevant to applicants aligning their work with institute missions: 93.242 (Mental Health Research Grants), 93.361 (Nursing Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.866 (Aging Research). For full details, NIH provided an additional information link to the Grants Guide posting, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact.

In summary, PA-09-017 sought well-developed R01 proposals aimed at improving the clinical diagnosis and medical management of HIV and its downstream health consequences in older adults, leveraging multidisciplinary perspectives spanning aging, infectious diseases, mental health research on HIV/AIDS, and nursing science. The opportunity emphasized practical clinical and translational relevance, offered broad organizational eligibility (including foreign entities), required no cost sharing, and made awards based on available funds and peer-reviewed scientific merit.

Frequently Asked Questions (FAQs)

What is the "Medical Management of Older Patients with HIV/AIDS (R01)" funding opportunity?

PA-09-017 is an NIH discretionary grant opportunity that supports research to improve how HIV is diagnosed and medically managed in older adults. It emphasizes clinical and translational research focused on real-world medical issues that arise as people age with HIV, including the consequences of long-term infection and long-term treatment.

What is the main goal of PA-09-017?

The core aim is to fund studies that improve clinical diagnosis and medical management of HIV in older patients, with attention to complex comorbidities and care delivery challenges common in aging populations living with HIV. The opportunity highlights practical relevance to patient care and encourages connecting clinical observations to mechanisms or interventions.

What types of research does this FOA emphasize?

The FOA emphasizes clinical and translational work grounded in patient care. It is intended for studies that address medical issues in older adults with HIV, including downstream health consequences of long-term infection and treatment, and the complicated comorbidities and care-delivery challenges that can occur with aging.

Which NIH components sponsor this opportunity?

The announcement is sponsored by multiple NIH components: the National Institute on Aging (NIA), the National Institute of Allergy and Infectious Diseases (NIAID), the Center for Mental Health Research on AIDS within the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR).

What does the mix of NIH sponsors suggest about the program's priorities?

Taken together, the sponsors signal interest in research that spans aging, infectious disease, mental health aspects of HIV/AIDS, and nursing research. This points to a multidisciplinary focus on patient-centered clinical questions, translational approaches, and complex comorbidities and care challenges in older people living with HIV.

What grant mechanism does PA-09-017 use?

This funding opportunity uses the NIH Research Project Grant (R01) mechanism, which typically supports mature, hypothesis-driven projects with a well-developed research plan and sufficient preliminary data.

How is PA-09-017 related to PA-09-018 and PA-09-019?

PA-09-017 is part of a coordinated set of opportunities with the same scientific scope offered under different grant mechanisms. NIH also offered PA-09-018 under the R03 (Small Research Grant) mechanism and PA-09-019 under the R21 (Exploratory/Developmental) mechanism, allowing investigators to choose a mechanism aligned with project size and stage.

When would an investigator choose PA-09-017 (R01) instead of the related R03 or R21 options?

Based on the description provided, PA-09-017 is intended for more comprehensive projects that require greater time, resources, and a broader investigative approach than an R03 or many R21 projects.

Is funding guaranteed under this opportunity?

No. Awards depend on the availability of appropriated funds and on the number of applications submitted that are judged highly meritorious through NIH peer review.

What is the maximum award amount listed for PA-09-017?

The listing includes an award ceiling of $500,000, which generally functions as an upper boundary for the opportunity as published. Actual award size and structure would follow NIH policy and institute-specific budget guidance at the time.

Is cost sharing or matching required?

No. The opportunity states that no cost sharing or matching is required.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education; nonprofits with or without 501(c)(3) status (including community-based and faith-based organizations); for-profit organizations (including small businesses and other for-profit entities); and many government entities such as state, county, and city/township governments, special district governments, independent school districts, and public housing authorities.

Are tribal entities and minority-serving institutions included in eligibility?

Yes. The announcement explicitly includes tribal governments and tribal organizations (federally recognized and other than federally recognized), tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, and Historically Black Colleges and Universities.

Are U.S. territories or possessions eligible to apply?

Yes. The announcement includes U.S. territories or possessions and certain regional organizations among eligible applicants.

Are non-U.S. (foreign) organizations eligible?

Yes. The opportunity explicitly includes non-U.S. entities (foreign organizations) as eligible applicants, indicating NIH openness to internationally based expertise and study populations when scientifically justified and compliant with NIH requirements.

When was the FOA posted, and what were the listed closing dates?

The FOA was posted on October 29, 2008. Closing dates were listed as January 7, 2012 (original) and May 7, 2012 (current at the time of the record).

What is the archive date for this opportunity?

The opportunity was archived on June 7, 2012.

Which CFDA numbers are associated with this opportunity?

The associated CFDA numbers listed are 93.242 (Mental Health Research Grants), 93.361 (Nursing Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.866 (Aging Research).

How are applications selected for award?

Applications are evaluated through NIH peer review, and awards are made based on scientific merit (as judged through peer review) and the availability of appropriated funds.

Where did NIH direct applicants for additional information and technical issues?

NIH provided an additional information link to the Grants Guide posting for full details. Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact.

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