Opportunity Information: Apply for PA 10 062

  • The National Institutes of Health in the education employment, labor and training food and nutrition health income security and social services sector is offering a public funding opportunity titled "Mentored Quantitative Research Development Award (Parent K25)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Apr 8, 2011 and posted on Dec 17, 2009.
  • Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Private institutions of higher education City or township governments Small businesses For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Independent school districts Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Mentored Quantitative Research Development Award (Parent K25), Funding Opportunity Number PA 10-062, is a National Institutes of Health (NIH) career development grant designed to bring experienced quantitative scientists and engineers into NIH-relevant biomedical and behavioral research. The central idea is to attract investigators whose careers have been grounded in fields like mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and other engineering or quantitative disciplines, but whose prior work has not focused primarily on health and disease. Through mentored training and a structured research plan, the award is meant to help these professionals translate their quantitative expertise into impactful health-related research questions and build a sustained trajectory in NIH-focused research areas.

This opportunity uses the K25 grant mechanism, which supports a mentored period of career development. In practical terms, the award provides funding and protected time so the recipient can pursue supervised study and research under the guidance of an experienced mentor (or mentoring team). The mentored structure is a core feature: applicants are expected to propose a plan that deliberately fills gaps in biomedical knowledge, domain methods, or translational context while leveraging their quantitative strengths. The goal is not only to fund a single project, but to support a broader transition into health-related research independence by combining training, mentorship, and a coherent research agenda.

NIH notes that awards under this announcement depend on the availability of funds and the volume and quality of applications received, meaning there is no guaranteed number of awards. Applicants are also encouraged to contact the relevant NIH Institute or Center (IC) staff ahead of submission to confirm institute-specific expectations and to clarify programmatic fit and budget issues, since NIH IC priorities and implementation details can vary. The announcement includes a table of Institute and Center contacts for that purpose.

The funding opportunity is listed under multiple CFDA numbers, reflecting that many NIH Institutes and Centers may participate and that K25-supported projects can span a wide range of disease areas and health topics. These include, among others, oral health, genomics, deafness and communication disorders, sleep, drug abuse and addiction, mental health career development, technology innovations to improve human health, cancer (diagnosis, treatment, and biology), cardiovascular, lung, and blood research, arthritis and musculoskeletal/skin diseases, diabetes/digestive/kidney diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, microbiology and infectious diseases, general biomedical research and training, child health and human development, and aging research. The breadth of these categories underscores that the key eligibility hinge is not a specific disease focus, but the candidate profile (quantitative background) and the intent to pivot toward NIH-relevant health and disease research.

In terms of who may apply, eligibility is broad at the organizational level and includes many types of U.S.-based entities such as state, county, city or township governments; special district governments; public and Indian housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities); small businesses and other for-profit organizations; and tribal governments and tribal organizations (including federally recognized tribes). The announcement also explicitly includes certain institution types and communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. There is no cost sharing or matching requirement stated for this opportunity.

Key administrative details from the listing include an initial posting date of December 17, 2009, with later record creation reflected as April 8, 2011, and archived status as of June 7, 2011. The original closing date is shown as January 7, 2012, with a current closing date of May 7, 2011 in the provided record, indicating the listing reflects a specific window or update history tied to the parent announcement. Applicants are directed to the full announcement on the NIH Grants Guide website (http://grants.nih.gov/grants/guide/pa-files/PA-10-062.html) for the complete requirements, and NIH provides a general contact (the NIH Office of Extramural Research webmaster) for technical access issues related to the electronic announcement or broken links.

Frequently Asked Questions (FAQs)

What is the Mentored Quantitative Research Development Award (Parent K25)?

The Mentored Quantitative Research Development Award (Parent K25) is an NIH career development grant opportunity designed to bring experienced quantitative scientists and engineers into NIH-relevant biomedical and behavioral research through a mentored, structured career development period.

What is the Funding Opportunity Number for this grant?

The Funding Opportunity Number (FON) is PA 10-062.

What does "Parent K25" mean in this context?

"Parent K25" refers to the K25 grant mechanism used for this opportunity, which supports a mentored period of career development rather than an unmentored, independent award.

What is the main purpose of this K25 opportunity?

The central purpose is to help investigators with strong quantitative backgrounds transition into health- and disease-focused research that aligns with NIH biomedical and behavioral priorities, by pairing them with mentorship and a deliberate training and research plan.

Who is this award intended to attract?

This award is intended to attract experienced quantitative scientists and engineers whose careers have been grounded in quantitative disciplines but whose prior work has not focused primarily on health and disease.

Which quantitative backgrounds are specifically mentioned?

The announcement highlights fields such as mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and other engineering or quantitative disciplines.

Is prior experience in health and disease research required?

The opportunity is specifically framed for investigators whose prior work has not focused primarily on health and disease, and who are seeking to translate their quantitative expertise into impactful health-related research questions through mentored training.

What does the mentored structure involve?

The award supports a supervised period of study and research under an experienced mentor (or mentoring team). Applicants are expected to propose a structured plan that addresses gaps in biomedical knowledge, domain methods, or translational context while leveraging their quantitative strengths.

Does the K25 support protected time for career development?

Yes. The K25 is described as providing funding and protected time so the recipient can pursue mentored study and research as part of a structured career development plan.

Is the goal to fund only a single research project?

No. The stated goal is broader than a single project: it is intended to support a transition toward health-related research independence by combining training, mentorship, and a coherent research agenda.

Are awards guaranteed under this announcement?

No. NIH notes that awards depend on the availability of funds and on the volume and quality of applications received, and therefore there is no guaranteed number of awards.

Should applicants contact NIH staff before submitting an application?

Yes. Applicants are encouraged to contact the relevant NIH Institute or Center (IC) staff ahead of submission to confirm institute-specific expectations and to clarify programmatic fit and budget issues.

Why might contacting an NIH Institute or Center (IC) matter?

The opportunity notes that NIH IC priorities and implementation details can vary, so discussing programmatic fit, expectations, and budget considerations with the appropriate IC can help clarify what that IC is looking for.

How broad is the range of research topics supported?

The opportunity is listed under multiple CFDA numbers and indicates that many NIH Institutes and Centers may participate, meaning K25-supported projects can span a wide range of disease areas and health topics.

What kinds of health or disease areas are mentioned?

Examples mentioned include oral health; genomics; deafness and communication disorders; sleep; drug abuse and addiction; mental health career development; technology innovations to improve human health; cancer; cardiovascular, lung, and blood research; arthritis and musculoskeletal/skin diseases; diabetes/digestive/kidney diseases; neuroscience and neurological disorders; allergy/immunology/transplantation; microbiology and infectious diseases; general biomedical research and training; child health and human development; and aging research.

Is a specific disease focus required to apply?

The listing emphasizes that the key eligibility hinge is not a specific disease focus, but the candidate profile (quantitative background) and the intent to pivot toward NIH-relevant health and disease research.

What types of organizations are eligible to apply?

Eligible applicant organizations include many U.S.-based entities such as state, county, city, or township governments; special district governments; public and Indian housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities); small businesses and other for-profit organizations; and tribal governments and tribal organizations (including federally recognized tribes).

Are U.S. territories or possessions included among eligible applicants?

Yes. The announcement explicitly includes U.S. territories or possessions among the types of eligible entities.

Does the eligibility list specifically mention minority-serving or community-based institutions?

Yes. It explicitly includes institution types and communities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, and regional organizations.

Is there a cost sharing or matching requirement?

No. The listing states that there is no cost sharing or matching requirement for this opportunity.

When was this opportunity posted and what is its status?

The listing shows an initial posting date of December 17, 2009, later record creation reflected as April 8, 2011, and indicates archived status as of June 7, 2011.

What application closing date should applicants rely on based on the record?

The provided record shows an original closing date of January 7, 2012, and a current closing date of May 7, 2011, suggesting the listing reflects a specific window or update history tied to the parent announcement.

Where can applicants find the complete official requirements?

Applicants are directed to the full announcement on the NIH Grants Guide website at http://grants.nih.gov/grants/guide/pa-files/PA-10-062.html for complete requirements.

Who should be contacted for technical access issues with the online announcement?

NIH provides a general contact for technical access issues related to the electronic announcement or broken links: the NIH Office of Extramural Research webmaster.

What does it mean that the opportunity is listed under multiple CFDA numbers?

It indicates that many NIH Institutes and Centers may participate and that K25-supported projects can align with a wide range of NIH program areas and health topics, rather than being limited to a single narrow category.

What is the core "fit" this program is looking for?

Based on the listing, the core fit is an investigator with established quantitative training/experience who proposes a mentored training and research plan aimed at translating that expertise into NIH-relevant biomedical or behavioral research focused on health and disease.

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