Opportunity Information: Apply for PA 10 056

  • The National Institutes of Health in the education employment, labor and training environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Mentored Research Scientist Development Award (Parent K01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.389 National Center for Research Resources 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Apr 8, 2011 and posted on Dec 16, 2009.
  • Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Private institutions of higher education Small businesses For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Mentored Research Scientist Development Award (Parent K01), Funding Opportunity Number PA 10-056, is an NIH career development grant designed to help promising researchers build the skills, track record, and focus needed to become independent investigators. The central aim is to provide substantial protected time for an intensive, mentored career development period lasting three, four, or five years. During that time, the award supports a structured plan that combines supervised research with targeted training and professional development in the biomedical, behavioral, or clinical sciences, with the clear end goal of positioning the awardee to compete successfully for independent research funding.

A defining feature of the K01 is the emphasis on mentorship and a deliberate transition toward independence. Applicants propose a career development plan and research project to be carried out under the guidance of an experienced mentor (and often a mentoring team), typically at an eligible research institution. While the overall K01 mechanism is used across many NIH Institutes and Centers (ICs) to support the research independence pathway, the announcement notes that some ICs also use the K01 more strategically. In practice, that can include supporting established scientists who are retooling into a new scientific area, as well as individuals returning to research after a significant career interruption due to illness or major family obligations. Some ICs also leverage the K01 to strengthen research workforce diversity by expanding high-quality mentored development opportunities for scientists from groups that are underrepresented in the biomedical research enterprise. Because priorities, expectations, and budget details can vary by IC, prospective applicants are encouraged to contact NIH program staff for institute-specific guidance before applying.

This opportunity is categorized as a discretionary grant and uses the K01 funding instrument. Awards are not guaranteed; the number of awards and total funds available depend on NIH appropriations and the volume and quality of applications received. In other words, funding decisions are contingent on both available funds and the submission of a sufficient number of meritorious applications.

The breadth of NIH participation is reflected in the many CFDA program areas associated with the announcement, spanning topics such as environmental health, human genome research, deafness and communication disorders, complementary and integrative health, sleep disorders, drug abuse and addiction, mental health, technology innovations for human health, nursing research, cancer research (detection, diagnosis, treatment, biology), cardiovascular and lung diseases, blood disorders, arthritis and musculoskeletal/skin diseases, diabetes/digestive/kidney diseases, neurosciences and neurological disorders, allergy/immunology/transplantation, microbiology and infectious diseases, child health and human development, and aging research. This broad coverage signals that the K01 is intended to be flexible and relevant to many research domains, as long as the proposed mentored training and research plan aligns with the mission of the chosen NIH IC.

Eligibility for submitting institutions is expansive and includes public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations), small businesses, for-profit organizations (including those other than small businesses), and a range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing/Indian housing authorities. The announcement also explicitly lists additional eligible applicants and institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, certain tribal organizations, and U.S. territories or possessions. While institutions submit applications, the award is fundamentally centered on supporting an individual candidate’s mentored development toward independence within an appropriate research environment.

Key administrative details included in the source information indicate the opportunity was posted on December 16, 2009, with an archive date of June 7, 2011, and it does not require cost sharing or matching. The full announcement and specifics are available through NIH’s grants guide at the provided link (http://grants.nih.gov/grants/guide/pa-files/PA-10-056.html). For technical access issues, the NIH Office of Extramural Research provides support through the OER webmaster contact listed in the notice.

FAQs: NIH Mentored Research Scientist Development Award (Parent K01) - PA 10-056

What is the Mentored Research Scientist Development Award (Parent K01)?

The Mentored Research Scientist Development Award (Parent K01) is an NIH career development grant intended to help promising researchers build the skills, publication record, and research focus needed to become independent investigators.

What is the main goal of this K01 opportunity?

The central aim is to provide substantial protected time for an intensive, mentored career development period so the awardee can transition toward research independence and become competitive for independent research funding.

How long can the mentored career development period last?

The mentored career development period supported by this award lasts three, four, or five years.

What does the K01 support during the award period?

The award supports a structured plan that combines supervised research with targeted training and professional development in the biomedical, behavioral, or clinical sciences.

Is mentorship required for a K01 application?

Yes. A defining feature of the K01 is the emphasis on mentorship. Applicants propose a career development plan and a research project carried out under the guidance of an experienced mentor, and often a mentoring team.

Where is the mentored research typically conducted?

The mentored research is typically conducted at an eligible research institution that can provide an appropriate research environment for the candidate's development toward independence.

What is meant by a "deliberate transition toward independence"?

It refers to the K01's focus on structured mentored development with the clear end goal of positioning the awardee to compete successfully for independent research funding.

Is the K01 used the same way across all NIH Institutes and Centers (ICs)?

Not necessarily. While the K01 mechanism is broadly used to support the pathway to research independence, some NIH ICs use the K01 more strategically and may have different priorities, expectations, or budget details.

Can established scientists apply if they are changing research areas?

In practice, some NIH ICs may use the K01 to support established scientists who are retooling into a new scientific area.

Can someone returning to research after a career interruption be supported under this K01?

Yes. The announcement notes that some ICs may use the K01 to support individuals returning to research after a significant career interruption due to illness or major family obligations.

Does this K01 relate to research workforce diversity efforts?

Some ICs leverage the K01 to strengthen research workforce diversity by expanding high-quality mentored development opportunities for scientists from groups that are underrepresented in the biomedical research enterprise.

Should applicants contact NIH staff before applying?

Yes. Because priorities, expectations, and budget details can vary by NIH Institute or Center, prospective applicants are encouraged to contact NIH program staff for institute-specific guidance before applying.

What type of grant is this (mandatory vs. discretionary)?

This opportunity is categorized as a discretionary grant.

What is the funding instrument used for this opportunity?

This opportunity uses the K01 funding instrument.

Are awards guaranteed if an application is submitted?

No. Awards are not guaranteed. The number of awards and total funds available depend on NIH appropriations and on the volume and quality of applications received.

What factors affect whether NIH makes awards under this announcement?

Funding decisions are contingent on available funds and the submission of a sufficient number of meritorious applications.

What research areas can be supported by this Parent K01?

The K01 is intended to be flexible and relevant to many research domains, as long as the proposed mentored training and research plan aligns with the mission of the chosen NIH Institute or Center.

Which NIH topic areas are associated with this announcement?

The associated CFDA program areas span a wide range, including environmental health; human genome research; deafness and communication disorders; complementary and integrative health; sleep disorders; drug abuse and addiction; mental health; technology innovations for human health; nursing research; cancer research; cardiovascular and lung diseases; blood disorders; arthritis and musculoskeletal/skin diseases; diabetes/digestive/kidney diseases; neurosciences and neurological disorders; allergy/immunology/transplantation; microbiology and infectious diseases; child health and human development; and aging research.

Who can submit an application as the institution?

Eligible submitting institutions include public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); small businesses; for-profit organizations (including those other than small businesses); and a range of government entities such as state, county, city or township, and special district governments, as well as independent school districts and public housing/Indian housing authorities.

Are minority-serving institutions and tribal entities eligible to apply?

Yes. The announcement explicitly lists additional eligible applicants and institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, certain tribal organizations, and U.S. territories or possessions.

Are faith-based or community-based organizations eligible to apply?

Yes. Faith-based and community-based organizations are explicitly listed among eligible applicants.

If institutions submit applications, who is the award actually centered on?

While institutions submit applications, the award is fundamentally centered on supporting an individual candidate's mentored development toward independence within an appropriate research environment.

Does this opportunity require cost sharing or matching?

No. The source information states that cost sharing or matching is not required.

When was this opportunity posted, and when was it archived?

The opportunity was posted on December 16, 2009, and has an archive date of June 7, 2011.

Where can applicants find the full announcement?

The full announcement is available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PA-10-056.html.

Who should be contacted for technical access issues related to the notice?

For technical access issues, the NIH Office of Extramural Research provides support through the OER webmaster contact listed in the notice.

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