Opportunity Information: Apply for PA 11 190

  • The National Institutes of Health in the education employment, labor and training health income security and social services sector is offering a public funding opportunity titled "Mentored Research Scientist Development Award (Parent K01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.351 Research Infrastructure Programs 93.361 Nursing Research 93.389 National Center for Research Resources 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Dec 19, 2013 and posted on Apr 8, 2011.
  • Applicants must submit their applications by Jan 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal governments (Federally recognized) Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education State governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Organizations) are not eligible to apply. Foreign (non U.S.) components of U.S. Organizations are not allowed.
Apply for PA 11 190

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Opportunity Summary:

The Mentored Research Scientist Development Award (Parent K01) is an NIH career development grant designed to help promising researchers move toward research independence through an intensive, structured, and closely supervised mentored experience. The core idea is to buy the candidate substantial protected time, typically over three, four, or five years, so they can build the skills, publication record, preliminary data, and professional trajectory needed to become an independent investigator in the biomedical, behavioral, or clinical sciences. In practice, the K01 is meant to function as a bridge between earlier training or early-career positions and the point where someone is competitive for independent research funding, with a strong emphasis on a well-justified career development plan and high-quality mentoring.

While the overall purpose is consistent across NIH, the announcement notes that NIH Institutes and Centers (ICs) can use the K01 in slightly different ways depending on their missions and workforce needs. For many ICs, the K01 primarily supports a standard pathway toward independence for early-stage scientists who need time and mentorship to deepen their expertise and research program. Some ICs also encourage K01 applications from researchers who are proposing to retrain into a new scientific field, which can be important for people pivoting into emerging areas or adding major new competencies (for example, moving into computational methods, clinical research methods, or a different disease area). In addition, certain ICs may consider K01 support for individuals whose research careers were interrupted because of major life events such as illness or pressing family circumstances, using the award as a structured way to reenter the research pipeline. The opportunity also highlights that some ICs use the K01 mechanism to strengthen research workforce diversity by offering enhanced career development support to individuals from groups underrepresented in biomedical research, though the exact expectations and emphases can vary by IC.

This is a discretionary grant opportunity from the National Institutes of Health, issued under Funding Opportunity Number PA-11-190 and titled "Mentored Research Scientist Development Award (Parent K01)." The activity spans several broad federal activity categories, including education and training and health-related research and career development. The announcement is linked to multiple CFDA program areas across NIH, reflecting that K01 awards can be supported by many Institutes and Centers depending on the scientific topic and fit with an IC mission. These include areas such as human genome research, communication disorders, complementary and integrative health, sleep disorders, drug abuse and addiction, mental health research career development, technological innovations to improve human health, research infrastructure, nursing research, cardiovascular and lung diseases, blood diseases, arthritis and musculoskeletal conditions, neuroscience and neurological disorders, allergy and immunology, infectious diseases, child health and human development, and aging research.

Eligible applicant organizations are broad and include many types of U.S.-based institutions and governments. Examples listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. The eligibility list also includes state, county, city or township, and special district governments, as well as Native American tribal governments and tribal organizations. The announcement further clarifies that other eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, Indian/Native American tribal governments that are not federally recognized, and U.S. territories or possessions. A key restriction is that non-U.S. (foreign) organizations are not eligible to apply, and foreign components of U.S. organizations are not allowed under this opportunity. The announcement also specifies that there is no cost sharing or matching requirement.

Because NIH ICs can differ in their program priorities and budgetary limits for K01s, prospective candidates are encouraged to contact the relevant NIH program staff for institute-specific guidance, including expectations about scope, allowable costs, and how the proposed mentored research and career development plan should align with the IC mission. The official funding announcement is available through NIH at the provided link, and the NIH Office of Extramural Research (OER) provides webmaster contacts for technical issues accessing the full notice. The opportunity was originally posted on April 8, 2011, with administrative dates indicating later record creation and closing/archive timelines; applicants would rely on the NIH notice for the authoritative submission dates and any updates.

Frequently Asked Questions (FAQs)

What is the Mentored Research Scientist Development Award (Parent K01)?

The Mentored Research Scientist Development Award (Parent K01) is an NIH career development grant designed to help promising researchers progress toward research independence through an intensive, structured, and closely supervised mentored experience.

What is the main goal of the K01 award?

The main goal is to provide substantial protected time, typically over three, four, or five years, so a candidate can build the skills, publication record, preliminary data, and professional trajectory needed to become an independent investigator in the biomedical, behavioral, or clinical sciences.

How does the K01 function in a research career pathway?

In practice, the K01 is intended to serve as a bridge between earlier training or early-career positions and the point where someone becomes competitive for independent research funding, with strong emphasis on a well-justified career development plan and high-quality mentoring.

Is the K01 used the same way across all NIH Institutes and Centers (ICs)?

No. The announcement notes that NIH Institutes and Centers can use the K01 in slightly different ways depending on their missions and workforce needs. While the overall purpose is consistent, expectations and emphases may vary by IC.

Can the K01 support researchers who are retraining into a new scientific field?

Yes, some NIH Institutes and Centers encourage K01 applications from researchers proposing to retrain into a new scientific field. This can support pivots into emerging areas or the addition of major new competencies (for example, moving into computational methods, clinical research methods, or a different disease area).

Can the K01 be used to help researchers reenter the workforce after a career interruption?

Yes. The opportunity describes that certain NIH Institutes and Centers may consider K01 support for individuals whose research careers were interrupted due to major life events such as illness or pressing family circumstances, using the award as a structured way to reenter the research pipeline.

Does this opportunity include a focus on strengthening diversity in the research workforce?

The opportunity highlights that some NIH Institutes and Centers use the K01 mechanism to strengthen research workforce diversity by offering enhanced career development support to individuals from groups underrepresented in biomedical research. Specific expectations can vary by IC.

What is the Funding Opportunity Number and official title?

The Funding Opportunity Number is PA-11-190, and the title is "Mentored Research Scientist Development Award (Parent K01)."

Which agency is offering this grant opportunity?

This is a discretionary grant opportunity from the National Institutes of Health (NIH).

What broad activity categories does this award fall under?

The activity spans broad federal categories including education and training and health-related research and career development.

What scientific areas can this K01 support?

The announcement is linked to multiple CFDA program areas across NIH, reflecting that K01 awards can be supported by many Institutes and Centers depending on scientific topic and mission fit. Examples listed include human genome research, communication disorders, complementary and integrative health, sleep disorders, drug abuse and addiction, mental health research career development, technological innovations to improve human health, research infrastructure, nursing research, cardiovascular and lung diseases, blood diseases, arthritis and musculoskeletal conditions, neuroscience and neurological disorders, allergy and immunology, infectious diseases, child health and human development, and aging research.

What types of organizations are eligible to apply?

Eligible applicant organizations are broad and include many types of U.S.-based institutions and governments. Examples listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses.

Are government entities eligible to apply?

Yes. The eligibility list includes state, county, city or township, and special district governments, as well as Native American tribal governments and tribal organizations.

Are minority-serving and other special types of institutions eligible?

Yes. The announcement clarifies eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Are faith-based or community-based organizations eligible?

Yes. Faith-based or community-based organizations are explicitly listed as eligible applicants.

Are non-federally recognized tribal governments eligible?

Yes. The opportunity includes Indian/Native American tribal governments that are not federally recognized as eligible applicants.

Are U.S. territories or possessions eligible to apply?

Yes. U.S. territories or possessions are included in the eligibility list.

Are foreign (non-U.S.) organizations eligible to apply?

No. Non-U.S. (foreign) organizations are not eligible to apply under this opportunity.

Are foreign components of U.S. organizations allowed?

No. The announcement states that foreign components of U.S. organizations are not allowed for this opportunity.

Is cost sharing or matching required?

No. The announcement specifies that there is no cost sharing or matching requirement.

Why is it important to contact NIH program staff before applying?

Because NIH Institutes and Centers can differ in program priorities and budgetary limits for K01s, prospective candidates are encouraged to contact the relevant NIH program staff for institute-specific guidance. This can include expectations about scope, allowable costs, and how the proposed mentored research and career development plan should align with the IC mission.

Where can applicants find the official funding announcement and authoritative dates?

The official funding announcement is available through NIH via the provided link in the notice. Although the record includes posting and administrative timeline information (originally posted April 8, 2011, with later record creation and closing/archive timelines), applicants should rely on the NIH notice itself for authoritative submission dates and any updates.

Who should be contacted for technical issues accessing the full notice?

The NIH Office of Extramural Research (OER) provides webmaster contacts for technical issues accessing the full notice.

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