Opportunity Information: Apply for PAR 09 053
Apply for PAR 09 053
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Midcareer Investigator Award in Mouse Pathobiology Research (K26)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.389 National Center for Research Resources.
- This funding opportunity was created on Dec 18, 2008 and posted on Dec 18, 2008.
- Applicants must submit their applications by Jan 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Public housing authorities/Indian housing authorities Special district governments State governments City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Midcareer Investigator Award in Mouse Pathobiology Research (K26) is an NIH funding opportunity (PAR-09-053) created to strengthen the field of mouse pathobiology by supporting established, highly accomplished investigators at the midcareer stage. The central goal is to buy protected time for these pathobiologists so they can focus more heavily on mouse pathobiology research while also serving as mentors to newer investigators. A key feature of the program is that it is designed to reduce the awardee's burden from institutional service work and administrative duties, which often pull experienced scientists away from research and training responsibilities. In practice, the award is meant to preserve and amplify the impact of proven experts by giving them dedicated time to push the science forward and build the next generation of researchers.
This opportunity uses the NIH K26 mechanism, which is a career development-style award aimed at supporting investigators through protected effort rather than funding a large standalone research project in the way an R01 typically does. Funding under this announcement is contingent on the availability of NIH funds and on the quality and number of applications received, meaning there is no guaranteed number of awards. The budget component highlighted in the announcement focuses on salary and fringe benefits to support up to 50 percent effort, capped at the NIH extramural salary cap in effect at the time (noted as FY 2008: $191,300 annually). That translates to a maximum salary support of $95,650 per year for 50 percent effort, plus applicable fringe benefits, with the intent that this support directly enables the investigator to protect time for research and mentoring activities.
Eligible applicant organizations are broad and include many types of U.S. institutions and entities, such as public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (including small businesses, with the listing explicitly noting for-profits other than small businesses as eligible as well), and a range of government entities (state, county, city/township governments, special district governments), as well as tribal governments and tribal organizations. The eligibility list also explicitly includes various mission-driven institution types and community-based organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and U.S. territories or possessions. Even with this wide eligibility, the sponsoring institution is expected to have a well-established mouse pathobiology research and training program, provide a strong research environment, and show a real commitment to the candidate's continued development as a productive, independent investigator. In other words, the institution must be able to demonstrate that it has both the infrastructure and the culture to support high-quality mouse pathobiology work and meaningful mentoring.
The applicant (Project Director/Principal Investigator) must be an individual with the expertise, experience, and resources to carry out the proposed mouse pathobiology research and the mentoring component. The announcement reiterates NIH's standing encouragement for applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities. Only one PD/PI is allowed per application, so this is not a multiple-PI mechanism. The FOA also sets limits on how many applications an individual should submit: generally, applicants should not submit more than one application, with a narrow exception allowing two K26 applications only if the combined effort across both does not exceed 50 percent and each application is scientifically distinct and includes appropriate mentoring.
The announcement provides specific guidance on resubmissions and amendments, reflecting NIH policy changes occurring at that time. Resubmissions are allowed, but they must include an introduction that addresses the prior peer review critique (the Summary Statement). For applications intended for the January 25, 2009 due date and beyond, NIH limited most new applications and competing renewals to a single amendment (A1). For older, "grandfathered" applications submitted before January 25, 2009, two amendments (A1 and A2) were permitted, with NIH stating that any A2 would be expected no later than January 7, 2011, and that A2 submissions would not be accepted after that date. Importantly, the FOA states that renewals are not allowed, meaning recipients cannot submit a renewal application to extend the award under this same mechanism once the project period ends.
From an administrative standpoint, the opportunity was posted December 18, 2008, with an original and final closing date of January 7, 2012, and it was archived February 7, 2012. It is associated with CFDA number 93.389 and was issued by NIH through the National Center for Research Resources (NCRR), and it does not require cost sharing or matching. The practical takeaway is that this FOA was a time-limited NIH program focused on keeping top midcareer mouse pathobiologists productive and engaged in both research and mentorship by offsetting up to half of their professional effort through salary support, with strong expectations for an enabling institutional environment and a clear mentoring role for the awardee.
Frequently Asked Questions (FAQs)
What is the Midcareer Investigator Award in Mouse Pathobiology Research (K26)?
The Midcareer Investigator Award in Mouse Pathobiology Research (K26) is an NIH funding opportunity (PAR-09-053) intended to strengthen the field of mouse pathobiology by supporting established, highly accomplished investigators at the midcareer stage.
What is the main goal of this K26 opportunity?
The central goal is to buy protected time for midcareer mouse pathobiologists so they can focus more heavily on mouse pathobiology research while also serving as mentors to newer investigators.
How does this award help investigators in practice?
A key feature is reducing the awardee's burden from institutional service work and administrative duties that can pull experienced scientists away from research and training responsibilities. The award is meant to preserve and amplify the impact of proven experts by providing dedicated time for research and mentorship.
Is this award meant to fund a large research project like an R01?
No. This opportunity uses the NIH K26 mechanism, described as a career development-style award aimed at supporting investigators through protected effort rather than funding a large standalone research project in the way an R01 typically does.
What types of costs does the budget emphasize?
The budget component highlighted in the announcement focuses on salary and fringe benefits to support up to 50 percent effort (plus applicable fringe benefits), with the intent that this support directly enables the investigator to protect time for research and mentoring activities.
What is the maximum supported effort under this FOA?
The announcement highlights support for up to 50 percent effort.
Is there a salary cap for this award?
Yes. Salary support is capped at the NIH extramural salary cap in effect at the time (noted as FY 2008: $191,300 annually).
What does the salary cap mean in terms of maximum annual salary support at 50 percent effort?
Based on the FY 2008 NIH extramural salary cap referenced ($191,300), the maximum salary support for 50 percent effort is stated as $95,650 per year, plus applicable fringe benefits.
Are awards guaranteed under this funding opportunity?
No. Funding is contingent on the availability of NIH funds and on the quality and number of applications received, meaning there is no guaranteed number of awards.
Which NIH organization issued this FOA?
The opportunity was issued by NIH through the National Center for Research Resources (NCRR).
What is the FOA number for this opportunity?
The FOA is PAR-09-053.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.389.
Does this program require cost sharing or matching?
No. The FOA states that it does not require cost sharing or matching.
Who can apply as an eligible organization?
Eligible applicant organizations are broad and include many types of U.S. institutions and entities, including public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); for-profit organizations (including small businesses and for-profits other than small businesses); and a range of government entities (state, county, city/township, and special district governments), as well as tribal governments and tribal organizations.
Are mission-driven institutions like HBCUs or Hispanic-serving institutions eligible to apply?
Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and also includes faith-based or community-based organizations and U.S. territories or possessions.
Even if an institution is eligible, are there expectations about the research environment?
Yes. The sponsoring institution is expected to have a well-established mouse pathobiology research and training program, provide a strong research environment, and show a real commitment to the candidate's continued development as a productive, independent investigator.
What does NIH expect the institution to demonstrate?
The institution must be able to demonstrate that it has both the infrastructure and the culture to support high-quality mouse pathobiology work and meaningful mentoring.
Who is the applicant/PD/PI for this award expected to be?
The Project Director/Principal Investigator must be an individual with the expertise, experience, and resources to carry out the proposed mouse pathobiology research and the mentoring component.
Does the FOA encourage applications from specific groups?
Yes. The announcement reiterates NIH's standing encouragement for applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities.
Are multiple PDs/PIs allowed on one application?
No. Only one PD/PI is allowed per application; this is not a multiple-PI mechanism.
How many K26 applications can an individual submit under this guidance?
Generally, applicants should not submit more than one application. A narrow exception allows two K26 applications only if the combined effort across both does not exceed 50 percent, and each application is scientifically distinct and includes appropriate mentoring.
Are resubmissions allowed?
Yes. Resubmissions are allowed, but they must include an introduction that addresses the prior peer review critique (the Summary Statement).
How many amendments were allowed for applications due January 25, 2009 and beyond?
For applications intended for the January 25, 2009 due date and beyond, NIH limited most new applications and competing renewals to a single amendment (A1).
What were the amendment rules for older, "grandfathered" applications submitted before January 25, 2009?
For older, "grandfathered" applications submitted before January 25, 2009, two amendments (A1 and A2) were permitted. NIH stated that any A2 would be expected no later than January 7, 2011, and that A2 submissions would not be accepted after that date.
Are renewals allowed under this FOA?
No. The FOA states that renewals are not allowed, meaning recipients cannot submit a renewal application to extend the award under this same mechanism once the project period ends.
When was this funding opportunity posted and when did it close?
The opportunity was posted on December 18, 2008. It had an original and final closing date of January 7, 2012.
Is this FOA still active?
No. The FOA was archived on February 7, 2012.
What is the overall intent of the program, in plain terms?
The program was designed to keep top midcareer mouse pathobiologists productive and engaged in both research and mentorship by offsetting up to half of their professional effort through salary support, with strong expectations for a supportive institutional environment and a clear mentoring role for the awardee.
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