Opportunity Information: Apply for PA 08 151

  • The National Institutes of Health in the education employment, labor and training environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Midcareer Investigator Award in Patient Oriented Research (K24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.389 National Center for Research Resources 93.398 Cancer Research Manpower 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
  • This funding opportunity was created on Dec 19, 2008 and posted on Dec 9, 2008.
  • Applicants must submit their applications by Jan 7, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for PA 08 151

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Opportunity Summary:

The Midcareer Investigator Award in Patient Oriented Research (K24) is an NIH career development grant designed to strengthen the clinical research workforce by giving established clinician-scientists protected time to both conduct patient-oriented research and mentor the next generation of clinical investigators. The broader NIH aim behind programs like this is to maintain a strong, diverse pipeline of highly trained scientists across biomedical, behavioral, and clinical fields so the country has enough experienced researchers working in the right areas to meet public health and scientific needs.

This particular K24 opportunity focuses on midcareer health professionals who already hold a clinical doctorate (or an equivalent degree) and are typically at the Associate Professor level or its institutional equivalent. The award is structured around two connected goals. First, it helps midcareer clinician-scientists carve out dedicated, protected time to expand and sustain an active patient-oriented research (POR) program, which generally refers to research that involves direct interactions with human subjects and/or uses human-derived materials in ways that are closely linked to clinical investigation. Second, it formally supports these investigators in a mentoring role, with an emphasis on training clinical residents, clinical fellows, and junior clinical faculty who are learning how to design, conduct, and lead rigorous patient-oriented studies. In other words, the grant is not only about boosting the awardee's own research productivity, but also about building mentoring capacity that translates into more well-prepared clinical investigators over time.

A key feature of the program is that it is meant to sustain impact beyond a single career stage. NIH explicitly notes that if an award recipient continues to run an independent, peer-reviewed patient-oriented research program and remains actively engaged in mentoring new investigators, that person can continue contributing to the program's goals even after promotion to Full Professor. This highlights that the K24 is less about launching a career from scratch and more about consolidating and extending a midcareer investigator's ability to lead, innovate, and train others in patient-oriented research.

Administratively, this opportunity is offered by the National Institutes of Health as a discretionary grant mechanism under Funding Opportunity Number PA-08-151, titled "Midcareer Investigator Award in Patient Oriented Research (K24)." It spans many NIH-related research areas as reflected by the long list of CFDA numbers, covering fields such as environmental health, cancer, cardiovascular and lung diseases, diabetes and kidney diseases, mental health, neuroscience, aging, child health, vision research, infectious diseases, nursing research, and others. That breadth signals that the K24 is a cross-cutting career development mechanism that can support patient-oriented research mentoring in many clinical domains rather than being restricted to one narrow specialty area.

Eligibility for applicant organizations is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), small businesses, and for-profit organizations other than small businesses. The eligibility information also explicitly includes institutions that serve specific populations, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. The listing indicates no cost sharing or matching requirement for the opportunity.

The notice was posted in December 2008, with an original closing date listed as May 7, 2011, and a current closing date shown as January 7, 2009, with an archive date of January 8, 2009. For official details, NIH points applicants to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-08-151.html, and provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.

Frequently Asked Questions (FAQs): Midcareer Investigator Award in Patient Oriented Research (K24) - NIH (PA-08-151)

What is the Midcareer Investigator Award in Patient Oriented Research (K24)?

The K24 is an NIH career development grant designed to strengthen the clinical research workforce by providing established clinician-scientists with protected time to conduct patient-oriented research and to mentor the next generation of clinical investigators.

What is the main purpose of this K24 opportunity?

This opportunity is built around two connected goals: (1) supporting protected time for a midcareer clinician-scientist to expand and sustain an active patient-oriented research (POR) program, and (2) formally supporting that investigator's role in mentoring developing clinical investigators.

Who is this award intended for?

It is intended for midcareer health professionals who already hold a clinical doctorate (or an equivalent degree) and are typically at the Associate Professor level or the institutional equivalent.

What does NIH mean by "patient-oriented research" (POR) in this context?

In this context, patient-oriented research generally refers to research that involves direct interactions with human subjects and/or uses human-derived materials in ways that are closely linked to clinical investigation.

Is the K24 mainly a research award or a mentoring award?

It is both. The K24 is designed to increase an awardee's ability to sustain and grow an independent patient-oriented research program while also building mentoring capacity that helps train clinical investigators over time.

What kinds of mentees are emphasized under this program?

The program emphasizes mentoring clinical residents, clinical fellows, and junior clinical faculty who are developing the skills to design, conduct, and lead rigorous patient-oriented studies.

Does the K24 aim to "launch" a new investigator's career?

No. NIH describes this as a midcareer mechanism. The emphasis is on consolidating and extending the capacity of an established clinician-scientist to lead patient-oriented research and mentor others, rather than launching a career from scratch.

Can a K24 recipient continue contributing to the program's goals after becoming a Full Professor?

Yes. NIH explicitly notes that if the award recipient continues to run an independent, peer-reviewed patient-oriented research program and remains actively engaged in mentoring new investigators, they can keep contributing to the goals even after promotion to Full Professor.

Which agency offers this grant, and what is the funding opportunity number?

This opportunity is offered by the National Institutes of Health (NIH). The Funding Opportunity Number is PA-08-151, titled "Midcareer Investigator Award in Patient Oriented Research (K24)."

Is this opportunity limited to a single clinical specialty or disease area?

No. The opportunity is described as cross-cutting and spans many NIH-related research areas, reflected by a long list of CFDA numbers that cover numerous biomedical, behavioral, and clinical fields.

What research areas can this K24 support (in general terms)?

Based on the information provided, the scope is broad and includes areas such as environmental health, cancer, cardiovascular and lung diseases, diabetes and kidney diseases, mental health, neuroscience, aging, child health, vision research, infectious diseases, nursing research, and other NIH-related domains.

What types of organizations are eligible to apply?

Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), small businesses, and for-profit organizations other than small businesses.

Are institutions serving specific populations explicitly included as eligible?

Yes. The eligibility listing explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.

Is cost sharing or matching required?

No. The listing indicates there is no cost sharing or matching requirement for this opportunity.

When was this opportunity posted?

The notice was posted in December 2008.

What deadlines are shown for this opportunity?

The information provided lists an original closing date of May 7, 2011, a current closing date of January 7, 2009, and an archive date of January 8, 2009.

Where can applicants find the official announcement and details?

NIH points applicants to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-08-151.html.

Who is the contact for access or linking issues related to the announcement page?

NIH provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues (as referenced in the opportunity notice).

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