Opportunity Information: Apply for RFA GM 14 009
Apply for RFA GM 14 009
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Modeling of Infectious Disease Agent Study Centers of Excellence (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Apr 12, 2013 and posted on Apr 12, 2013.
- Applicants must submit their applications by Nov 26, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Independent school districts For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Small businesses Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) County governments Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Modeling of Infectious Disease Agent Study Centers of Excellence (U54) opportunity (Funding Opportunity Number RFA-GM-14-009) was a National Institutes of Health (NIH) cooperative agreement funding announcement aimed at building and supporting Centers of Excellence focused on infectious disease modeling. It was issued as a recompetition or reissuance of an earlier program announcement (RFA-GM-09-003) and was designed to strengthen the national capacity for computational and mathematical approaches that can inform real-world infectious disease preparedness and response.
At the core of the announcement is the MIDAS program (Modeling of Infectious Disease Agents Study), a coordinated network intended to connect multidisciplinary teams working in computational epidemiology and related fields. Under this structure, the Centers of Excellence funded through this FOA would operate as one major pillar of the broader MIDAS network, alongside a separate, centralized Information Technology Resource (announced under a different solicitation) and additional research projects (also announced separately). The basic idea is that the Centers are not meant to function as isolated research groups; instead, they are expected to contribute to a shared national modeling enterprise with common infrastructure, collaboration, and outputs that are useful beyond any single institution.
The overall purpose of MIDAS, as described in the announcement, is to coordinate a community of scientists who use computational, statistical, and mathematical research to deliver better resources, knowledge, and practical tools for the U.S. scientific and public health communities. The emphasis is on improving the ability to prepare for, detect, and reduce the spread of infectious diseases, whether those diseases emerge naturally (seasonal influenza, novel pathogens, etc.) or result from intentional release, including agents relevant to biodefense. In practice, that framing signals an expectation that the research produced by these Centers should be actionable, policy-relevant, and capable of supporting decision-making during outbreaks or public health emergencies.
The Centers funded under this FOA were expected to address four broad thematic areas. First is infectious disease research, meaning the substantive epidemiological and biological questions about how pathogens spread, what drives transmission dynamics, how interventions change outcomes, and how outbreaks behave across populations and settings. Second is computational, statistical, and mathematical research, reflecting that the program is specifically about modeling: developing, improving, validating, and applying models; working with complex data streams; and advancing the methods that make forecasts, scenario analysis, and intervention evaluation possible. Third is education and outreach, indicating that Centers should not only produce models, but also help others understand and use them by training researchers, building workforce capacity, and communicating modeling insights to non-specialists. Fourth is public health policy, highlighting that modeling is being funded in large part because of its value to planners and policymakers, so Centers are expected to engage with policy questions and translate technical results into forms that support public health action.
Administratively, the award mechanism was a U54 cooperative agreement, which generally implies substantial involvement from the funding agency compared with a standard research project grant. In cooperative agreements, NIH typically expects active programmatic coordination, participation in network activities, and alignment with shared goals and governance. The activity category was Health, and the CFDA listing included 93.859 (Biomedical Research and Research Training). The announcement stated there was no cost sharing or matching requirement.
In terms of funding scale and timing, the FOA listed an estimated total funding amount of $2,000,000. The opportunity was posted and created on April 12, 2013, with an original and current closing date of November 26, 2013, and an archive date of December 27, 2013. While the total estimated funding figure provides a sense of overall program investment, the specific number of awards and per-award budgets would typically be detailed in the full FOA text linked in the NIH guide notice.
Eligibility was broad across U.S.-based organizations and governments, including public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), state and local governments, tribal governments and tribal organizations, public housing authorities, special district governments, independent school districts, and for-profit organizations other than small businesses, as well as small businesses. The eligibility section also explicitly included various mission-focused institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. At the same time, the FOA clearly restricted participation to domestic entities: non-U.S. (foreign) institutions could not apply, non-U.S. components of U.S. organizations were not eligible, and foreign components (as defined by NIH policy) were not allowed.
For reference and official details, the announcement provided an NIH guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-009.html) and directed technical access questions to the NIH Office of Extramural Research (OER) webmaster contacts.
Frequently Asked Questions (FAQs)
What is the “Modeling of Infectious Disease Agent Study Centers of Excellence (U54)†opportunity?
This opportunity (Funding Opportunity Number RFA-GM-14-009) was a National Institutes of Health (NIH) cooperative agreement funding announcement focused on building and supporting Centers of Excellence dedicated to infectious disease modeling. It aimed to strengthen national capacity for computational and mathematical approaches that can support real-world infectious disease preparedness and response.
What program is this funding opportunity associated with?
The announcement is part of the MIDAS program (Modeling of Infectious Disease Agents Study), a coordinated network that connects multidisciplinary teams working in computational epidemiology and related fields.
Is this a new program or a recompetition/reissue?
It was issued as a recompetition or reissuance of an earlier program announcement, RFA-GM-09-003.
What is the purpose of the MIDAS program described in the announcement?
The stated purpose of MIDAS is to coordinate a community of scientists using computational, statistical, and mathematical research to deliver improved resources, knowledge, and practical tools for U.S. scientific and public health communities. The emphasis is on improving the ability to prepare for, detect, and reduce the spread of infectious diseases.
What kinds of infectious disease threats are within scope?
The scope includes diseases that emerge naturally (such as seasonal influenza or novel pathogens) as well as threats resulting from intentional release, including agents relevant to biodefense.
How are the Centers of Excellence expected to operate within MIDAS?
The Centers are described as a major pillar of the broader MIDAS network and are not intended to function as isolated research groups. They are expected to contribute to a shared national modeling enterprise with common infrastructure, collaboration, and outputs useful beyond any single institution.
Are there other MIDAS components besides the Centers of Excellence?
Yes. The announcement notes that MIDAS also includes a separate, centralized Information Technology Resource (announced under a different solicitation) and additional research projects (also announced separately).
What are the main thematic areas Centers were expected to address?
The announcement describes four broad thematic areas: (1) infectious disease research, (2) computational, statistical, and mathematical research (modeling methods and applications), (3) education and outreach, and (4) public health policy.
What does “infectious disease research†mean in the context of this FOA?
It refers to substantive epidemiological and biological questions such as how pathogens spread, what drives transmission dynamics, how interventions change outcomes, and how outbreaks behave across populations and settings.
What does the modeling/methods theme include?
It emphasizes developing, improving, validating, and applying models; working with complex data streams; and advancing methods that support forecasting, scenario analysis, and evaluation of interventions.
What is meant by “education and outreach†for these Centers?
Education and outreach indicates that Centers should not only produce models, but also help others understand and use them by training researchers, building workforce capacity, and communicating modeling insights to non-specialists.
Why is “public health policy†included as a thematic area?
The announcement highlights that modeling is funded in large part because of its value to planners and policymakers. Centers are expected to engage with policy questions and translate technical results into forms that support public health action.
What funding mechanism was used?
The award mechanism was a U54 cooperative agreement.
What does a U54 cooperative agreement imply about NIH involvement?
In general, a cooperative agreement implies substantial involvement from the funding agency compared with a standard research project grant. The announcement describes expectations for active programmatic coordination, participation in network activities, and alignment with shared goals and governance.
What is the activity category and CFDA listing mentioned?
The activity category was Health, and the CFDA listing included 93.859 (Biomedical Research and Research Training).
Is cost sharing or matching required?
No. The announcement stated there was no cost sharing or matching requirement.
What was the estimated total funding amount listed in the FOA?
The FOA listed an estimated total funding amount of $2,000,000.
Does the estimated total funding amount indicate the number of awards or award size?
Not by itself. The information provided notes that the specific number of awards and per-award budgets would typically be detailed in the full FOA text linked in the NIH guide notice.
When was this opportunity posted and when did it close?
It was posted/created on April 12, 2013. The original and current closing date was November 26, 2013.
When was the opportunity archived?
The archive date listed was December 27, 2013.
Who was eligible to apply?
Eligibility was broad across U.S.-based organizations and governments, including public and private institutions of higher education; nonprofits (with and without 501(c)(3) status); state and local governments; tribal governments and tribal organizations; public housing authorities; special district governments; independent school districts; for-profit organizations other than small businesses; and small businesses.
Are mission-focused or minority-serving institutions explicitly included in eligibility?
Yes. The eligibility section explicitly included institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs). It also included faith-based or community-based organizations and eligible federal agencies.
Are foreign organizations or foreign components eligible?
No. The FOA restricted participation to domestic entities. Non-U.S. (foreign) institutions could not apply, non-U.S. components of U.S. organizations were not eligible, and foreign components (as defined by NIH policy) were not allowed.
Where can applicants find the official NIH notice for this opportunity?
The announcement provided an NIH guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-009.html
Where were technical access questions directed?
The announcement directed technical access questions to the NIH Office of Extramural Research (OER) webmaster contacts.
What is the core expectation for impact or use of the research?
Based on the description provided, the research is expected to be actionable and policy-relevant, capable of supporting decision-making during outbreaks or public health emergencies, and useful beyond a single institution through network collaboration and shared outputs.
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