Opportunity Information: Apply for RFA NS 13 006
Apply for RFA NS 13 006
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Nov 28, 2012 and posted on Nov 23, 2012.
- Applicants must submit their applications by Jan 23, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- Eligible applicants include: Small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Private institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities City or township governments State governments Independent school districts County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50) opportunity (Funding Opportunity Number RFA-NS-13-006) is an NIH program run through the National Institute of Neurological Disorders and Stroke (NINDS) designed to support large, coordinated Parkinsons disease (PD) research centers. The main purpose is to build and maintain a network of Udall Centers that can work both collaboratively across institutions and independently within their own programs to clarify the causes of PD and speed the discovery of better treatments. Each funded Center is expected to function not just as a collection of separate labs, but as an integrated hub that can rapidly push forward basic, translational, and clinical research while also serving as a local resource and a national leader in PD research.
A central expectation of the program is that the Center has a unifying scientific theme and a set of research projects and shared resource cores that directly advance understanding of PD etiology (causes), pathogenesis (disease mechanisms), or treatment. Work on related parkinsonian disorders can be included, but only insofar as it clearly informs PD itself. NINDS places particular emphasis on basic science as the foundation for meaningful advances, so competitive applications are expected to include a strong, well-integrated basic research component that fits naturally into a broader multidisciplinary program.
Structurally, the announcement requires several specific components. First, the Center must include at least three interdisciplinary research projects. At least one of these projects must be translational in nature and focus on tangible paths toward patient impact, such as development of therapeutics, diagnostics, or clinical criteria that could ultimately enable new approaches to treating PD. Second, the application must propose the appropriate Research Cores needed to accomplish the projects, along with a required Administrative Core to coordinate the Center. These cores are meant to provide essential shared capabilities (for example, clinical characterization resources, biomarkers, imaging, neuropathology, genetics, data management, or model systems), but the exact cores should be justified by how they enable and accelerate the proposed projects. Third, the Center must present a concrete training plan to develop PD researchers, reflecting the program goal of strengthening the workforce and pipeline in Parkinsons research.
Beyond having the required parts on paper, the program is explicitly looking for true synergy. NINDS expects a considerable degree of integration among projects and cores, with clear evidence that the scientific aims cannot be achieved as effectively without the Center structure. In other words, the projects should cross-inform each other, share methods and data, and use the cores in ways that produce added value beyond what independent grants would deliver. The Udall Centers program is also intended to operate as a network, so Centers are expected to contribute to broader collaborative progress in the field, not only their institution-specific objectives.
From an administrative and funding standpoint, this is a discretionary grant mechanism using the NIH P50 specialized center format within the Health activity category. The CFDA listing is 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The opportunity was posted on Nov 23, 2012, with an application due date of Jan 23, 2013, and an archive date of Feb 23, 2013. The estimated total funding listed is $4,500,000, with an award ceiling of $1,500,000. Cost sharing is not required.
Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3)), small businesses, for-profit entities (other than small businesses), state and local governments, tribal governments and organizations, public housing authorities, and a range of mission-focused institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations, among others. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply; however, foreign components as defined under the NIH Grants Policy Statement are allowed, which typically means certain well-justified international collaborations can be included under NIH rules even though the applicant organization must be U.S.-based.
Overall, this opportunity is aimed at supporting highly coordinated, multidisciplinary PD centers that blend basic discovery with translational momentum, anchored by shared cores and leadership infrastructure, and paired with a deliberate plan to train the next generation of Parkinsons investigators. The distinguishing feature is the requirement for deep integration and synergy, with the Center model serving as the engine that makes the proposed science feasible and faster-moving than a set of loosely connected projects.
Frequently Asked Questions (FAQs): Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50)
What is this funding opportunity?
This opportunity supports the Morris K. Udall Centers of Excellence for Parkinsons Disease Research using the NIH P50 specialized center mechanism. It is a program run through the National Institute of Neurological Disorders and Stroke (NINDS) and is designed to fund large, coordinated Parkinsons disease (PD) research centers.
What is the Funding Opportunity Number and title?
The Funding Opportunity Number is RFA-NS-13-006. The opportunity title is "The Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50)."
What is the main goal of the Udall Centers program?
The main goal is to build and maintain a network of Udall Centers that can work collaboratively across institutions and also conduct integrated programs within their own centers to clarify the causes of PD and speed the discovery of better treatments.
What types of research are Udall Centers expected to support?
Centers are expected to support basic, translational, and clinical research in Parkinsons disease in a tightly integrated way, functioning as an organized hub rather than separate, independent labs.
Is there a preferred scientific emphasis within applications?
Yes. NINDS places particular emphasis on basic science as the foundation for meaningful advances. Competitive applications are expected to include a strong, well-integrated basic research component that fits naturally into a broader multidisciplinary program.
Does the Center need a unifying scientific theme?
Yes. A central expectation is that the Center has a unifying scientific theme, supported by research projects and shared resource cores that directly advance understanding of PD etiology (causes), pathogenesis (disease mechanisms), or treatment.
Can projects on related parkinsonian disorders be included?
Yes, but only if the work clearly informs Parkinsons disease itself. Related parkinsonian disorder work is acceptable insofar as it directly advances understanding of PD.
How many research projects are required in a Center application?
The announcement requires at least three interdisciplinary research projects as part of the Center.
Is a translational project required?
Yes. At least one of the required research projects must be translational in nature and focused on tangible paths toward patient impact.
What kinds of translational outcomes are expected?
The translational project is expected to focus on routes toward patient impact such as development of therapeutics, diagnostics, or clinical criteria that could ultimately enable new approaches to treating Parkinsons disease.
What cores are required?
The application must propose the appropriate Research Cores needed to accomplish the projects and must include a required Administrative Core to coordinate the Center.
What is the role of Research Cores in this program?
Research Cores provide essential shared capabilities that enable and accelerate the proposed projects. The specific cores should be justified based on how they support the projects and the overall Center theme.
What are examples of Research Core capabilities mentioned in the opportunity?
Examples include resources for clinical characterization, biomarkers, imaging, neuropathology, genetics, data management, or model systems. The opportunity notes these as illustrative examples rather than an exhaustive list.
What is the role of the Administrative Core?
The Administrative Core is required and is intended to coordinate the Center, supporting the leadership and organizational structure needed for integrated, multi-project work.
Is a training plan required?
Yes. The Center must present a concrete training plan to develop Parkinsons disease researchers, reflecting the program goal of strengthening the workforce and pipeline in PD research.
What does NINDS mean by "synergy" and integration?
The program is explicitly looking for true synergy across projects and cores. NINDS expects a considerable degree of integration, including shared methods and data, cross-informing aims, and meaningful use of cores that provides added value beyond what independent grants would deliver.
Why is the Center model important for this opportunity?
The Center model is expected to make the proposed science feasible and faster-moving than a loosely connected set of projects. Review expectations include clear evidence that the aims cannot be achieved as effectively without the integrated Center structure.
Are Centers expected to collaborate beyond their own institution?
Yes. The Udall Centers program is intended to operate as a network, and Centers are expected to contribute to broader collaborative progress in the field, not only their institution-specific objectives.
What agency and institute are sponsoring this opportunity?
This is an NIH opportunity run through the National Institute of Neurological Disorders and Stroke (NINDS).
What grant mechanism is used?
This is a discretionary grant mechanism using the NIH P50 specialized center format.
What is the activity category?
The activity category is Health.
What is the CFDA listing for this opportunity?
The CFDA listing is 93.853, titled "Extramural Research Programs in the Neurosciences and Neurological Disorders."
When was the opportunity posted and when were applications due?
The opportunity was posted on Nov 23, 2012. The application due date was Jan 23, 2013.
When was the opportunity archived?
The archive date was Feb 23, 2013.
How much total funding was estimated for this opportunity?
The estimated total funding listed is $4,500,000.
What is the award ceiling?
The award ceiling listed is $1,500,000.
Is cost sharing required?
No. Cost sharing is not required.
Who is eligible to apply?
Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education; nonprofits (including 501(c)(3) and non-501(c)(3)); small businesses; for-profit entities (other than small businesses); state and local governments; tribal governments and organizations; public housing authorities; and various mission-focused institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Are foreign institutions eligible to apply directly?
No. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply.
Are any international collaborations allowed?
Yes. While the applicant organization must be U.S.-based, foreign components (as defined under the NIH Grants Policy Statement) are allowed, meaning certain well-justified international collaborations may be included under NIH rules.
What makes a Center application competitive based on the description?
Based on the description, competitive applications emphasize a strong basic science foundation, include at least three interdisciplinary projects (with at least one translational project), propose well-justified shared cores plus an Administrative Core, include a concrete training plan, and demonstrate deep integration and synergy that shows clear added value from the Center structure.
What is the overall purpose of funding these Centers?
The overall purpose is to support highly coordinated, multidisciplinary Parkinsons disease centers that blend basic discovery with translational momentum, anchored by shared cores and leadership infrastructure, and paired with deliberate training of the next generation of PD investigators.
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