Opportunity Information: Apply for RFA DE 15 006
Apply for RFA DE 15 006
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Multidisciplinary and Collaborative Research Consortium to Reduce Oral Health Disparities in Children A Multilevel Approach (UH2/UH3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
- This funding opportunity was created on Jun 27, 2014 and posted on Jun 27, 2014.
- Applicants must submit their applications by Feb 27, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses City or township governments Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign Institutions Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity RFA-DE-15-006, titled "Multidisciplinary and Collaborative Research Consortium to Reduce Oral Health Disparities in Children: A Multilevel Approach (UH2/UH3)," supports research aimed at reducing or eliminating oral health disparities among vulnerable children and adolescents in the United States, specifically ages 0 through 21. The central idea is to move beyond single-factor solutions by encouraging teams to design, refine, and test interventions that work across multiple levels of influence, such as individual behaviors, family and caregiver contexts, community environments, clinical care delivery, and broader policies. The expectation is that these projects will generate practical, evidence-based approaches that can be validated and then spread more widely through real-world dissemination and implementation, ultimately preventing oral disease or improving access to effective treatment in populations that currently experience disproportionate burdens.
A defining feature of this opportunity is its emphasis on multidisciplinary, collaborative work and meaningful community engagement. Applicants are expected to bring together investigators from different fields and to partner with community organizations, schools, clinics, public health entities, or other stakeholders who can help ensure the research is grounded in real needs and feasible in real settings. Rather than focusing only on clinical outcomes in controlled environments, the program is designed to support holistic strategies that can address structural and social drivers of inequality, and to develop interventions or evaluate existing programs or policies that can realistically be adopted, sustained, and scaled.
The award uses the UH2/UH3 cooperative agreement mechanism, which is a two-phase structure with substantial NIH involvement typical of cooperative agreements. The first phase (UH2) is an exploratory and preparatory stage. UH2 funding is intended for planning and early groundwork, including feasibility testing and the development of key study materials such as the protocol and a Manual of Procedures. This phase is meant to ensure that the intervention or evaluation approach is well specified, operationally ready, and supported by the partnerships and infrastructure needed for successful execution. Projects in the UH2 phase must meet defined milestones; only those that do so will be administratively considered for transition to the second phase.
The second phase (UH3) is the implementation stage. In UH3, the project carries out the larger-scale study activities needed to test or evaluate the intervention, program, or policy and generate outcomes that can inform broader use. This structure encourages applicants to think through both phases from the beginning: applications must propose objectives for both UH2 and UH3, showing how early feasibility and planning work will directly enable full implementation and produce results that matter for reducing disparities in children’s oral health.
This funding opportunity is designed to operate as part of a consortium and runs in parallel with a companion solicitation for a Data Coordinating Center (RFA-DE-15-007). In practice, that means funded research teams are expected to function in a coordinated, collaborative environment where data harmonization, common measures, shared procedures, and cross-project learning can be supported centrally. The overall intent is to strengthen the quality, comparability, and impact of the research by pairing multiple intervention/evaluation projects with a dedicated coordinating infrastructure.
From an eligibility and administrative standpoint, the announcement is categorized as discretionary funding and uses a cooperative agreement as the funding instrument. It falls under the health activity category and is associated with CFDA 93.121 (Oral Diseases and Disorders Research). The NIH anticipated making about eight awards, with an estimated total funding level of $5,000,000, and no cost sharing or matching requirement. Eligible applicants are broad and include public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), state and local governments (including county and city/township governments), independent school districts, special district governments, public and Indian housing authorities, tribal governments (federally recognized and other tribal entities as specified), tribally controlled colleges and universities, regional organizations, faith-based and community-based organizations, eligible federal agencies, and for-profit organizations (other than small businesses), as well as small businesses. The announcement also highlights eligibility for several types of minority-serving institutions, including HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian serving institutions, and TCCUs. Foreign institutions and non-U.S. entities are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined in NIH policy are allowed.
Key dates in the source listing show the opportunity was posted June 27, 2014, with an original and current closing date of February 27, 2015, and an archive date of March 30, 2015. Overall, the opportunity is structured to push the field toward interventions and policies that do more than demonstrate effectiveness in theory. It is built to produce approaches that are feasible, community-informed, and ready for implementation, with the long-term goal of measurably reducing and ultimately eliminating oral health disparities and inequalities affecting U.S. children and youth.
Frequently Asked Questions (FAQs)
What is the funding opportunity RFA-DE-15-006?
RFA-DE-15-006 is a National Institutes of Health (NIH) funding opportunity titled "Multidisciplinary and Collaborative Research Consortium to Reduce Oral Health Disparities in Children: A Multilevel Approach (UH2/UH3)." It supports research projects designed to reduce or eliminate oral health disparities among vulnerable children and adolescents in the United States.
What is the main goal of this opportunity?
The goal is to generate practical, evidence-based interventions, programs, or policy approaches that can prevent oral disease or improve access to effective treatment for children and youth who experience disproportionate oral health burdens. A key focus is producing approaches that can be validated and then disseminated and implemented in real-world settings.
Who is the target population for the research?
The target population is vulnerable children and adolescents in the United States, specifically ages 0 through 21.
What does "oral health disparities" mean in the context of this announcement?
In this announcement, oral health disparities refers to unequal oral health outcomes or unequal access to effective prevention and treatment that disproportionately affect certain vulnerable groups of U.S. children and youth.
What kind of research approach does NIH want applicants to take?
NIH is encouraging applicants to move beyond single-factor solutions by designing, refining, and testing interventions that operate across multiple levels of influence. These levels can include individual behaviors, family and caregiver contexts, community environments, clinical care delivery, and broader policies.
What types of interventions or studies are envisioned?
Projects may focus on developing interventions or evaluating existing interventions, programs, or policies that can realistically be adopted, sustained, and scaled in real-world environments, with the aim of reducing disparities in children's oral health.
Why is the opportunity described as "multidisciplinary" and "collaborative"?
A defining feature is the expectation that applicants bring together investigators from different fields and work collaboratively, including meaningful engagement with communities and stakeholders who can help ensure the research is grounded in real needs and feasible in real settings.
What does "meaningful community engagement" imply for applicants?
Applicants are expected to partner with organizations and stakeholders such as community organizations, schools, clinics, public health entities, or other groups. The intent is to ensure that proposed strategies are relevant, practical, and implementable in the settings where children and families actually receive services.
What is the UH2/UH3 mechanism?
This opportunity uses the UH2/UH3 cooperative agreement mechanism, a two-phase award structure with substantial NIH involvement typical of cooperative agreements. The first phase (UH2) supports planning and early groundwork; the second phase (UH3) supports larger-scale implementation and evaluation activities.
What happens during the UH2 (exploratory and preparatory) phase?
UH2 funding supports planning and early groundwork, including feasibility testing and development of key study materials such as the protocol and a Manual of Procedures. The purpose is to ensure the approach is well specified and operationally ready, with partnerships and infrastructure in place.
Are there milestones required in the UH2 phase?
Yes. Projects in the UH2 phase must meet defined milestones. Only those that meet milestones will be administratively considered for transition to the UH3 phase.
What happens during the UH3 (implementation) phase?
UH3 supports implementation of the larger-scale study activities needed to test or evaluate the intervention, program, or policy and generate outcomes that can inform broader use for reducing disparities in children's oral health.
Do applications need to address both UH2 and UH3 from the start?
Yes. Applications must propose objectives for both phases and explain how UH2 feasibility and planning will enable UH3 implementation and produce meaningful results for reducing oral health disparities.
What does it mean that this is a cooperative agreement with substantial NIH involvement?
The award uses a cooperative agreement mechanism, which typically involves substantial NIH involvement in the execution of the project compared to standard grants. The announcement describes this as a defining feature of the mechanism used (UH2/UH3 cooperative agreement).
How does the consortium model affect funded projects?
Projects are expected to operate as part of a coordinated consortium environment. This includes expectations around collaboration, cross-project learning, and coordination that can support data harmonization, common measures, and shared procedures.
What is the companion solicitation mentioned in the announcement?
The opportunity runs in parallel with a companion solicitation for a Data Coordinating Center (RFA-DE-15-007). The intent is to pair multiple intervention/evaluation projects with dedicated coordinating infrastructure.
What role does the Data Coordinating Center (RFA-DE-15-007) play?
Based on the description, the Data Coordinating Center is intended to support the consortium by enabling coordinated functions such as data harmonization, use of common measures, shared procedures, and cross-project learning across funded research teams.
What is the anticipated number of awards and total funding level?
NIH anticipated making about eight awards, with an estimated total funding level of $5,000,000.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
What is the funding instrument and funding type?
The listing identifies the opportunity as discretionary funding and states the funding instrument is a cooperative agreement.
What is the activity category and CFDA number associated with this opportunity?
The opportunity is categorized under the health activity area and is associated with CFDA 93.121 (Oral Diseases and Disorders Research).
Who is eligible to apply?
Eligible applicants are broad and include public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); state and local governments (including county and city/township governments); independent school districts; special district governments; public and Indian housing authorities; tribal governments (federally recognized and other specified tribal entities); tribally controlled colleges and universities; regional organizations; faith-based and community-based organizations; eligible federal agencies; for-profit organizations (other than small businesses); and small businesses.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The announcement highlights eligibility for several minority-serving institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Asian American Native American Pacific Islander-serving institutions (AANAPISIs), Alaska Native and Native Hawaiian serving institutions, and Tribally Controlled Colleges and Universities (TCCUs).
Are foreign institutions or non-U.S. entities eligible to apply?
No. Foreign institutions and non-U.S. entities are not eligible to apply.
Can a U.S. organization include a non-U.S. component on the application?
No. Non-U.S. components of U.S. organizations are not eligible according to the announcement.
Are any foreign elements allowed at all?
Yes. The announcement states that foreign components, as defined in NIH policy, are allowed.
What are the key dates for this opportunity?
The source listing shows the opportunity was posted on June 27, 2014. The original and current closing date is February 27, 2015. The archive date is March 30, 2015.
What is the long-term intent of the program?
The long-term intent is to push the field toward interventions and policies that are feasible and community-informed, and that are ready for dissemination and implementation, with the ultimate goal of measurably reducing and eliminating oral health disparities affecting U.S. children and youth.
Does the program prioritize real-world implementation over controlled clinical settings?
Yes. The description emphasizes strategies grounded in real needs and feasible in real settings, and it notes a focus beyond clinical outcomes in controlled environments toward approaches that can be adopted, sustained, and scaled.
What kinds of settings and partners are specifically named as relevant to this work?
The announcement mentions partnering with community organizations, schools, clinics, public health entities, and other stakeholders who can help align research with community needs and real-world feasibility.
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