Opportunity Information: Apply for PA 16 102

  • The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Multidisciplinary Research in Vulvodynia (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
  • This funding opportunity was created on Feb 18, 2016 and posted on Feb 18, 2016.
  • Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PA 16 102

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Opportunity Summary:

The Multidisciplinary Research in Vulvodynia (R01) funding opportunity (PA-16-102) is a National Institutes of Health (NIH) research grant announcement from HHS/NIH focused on vulvodynia, commonly described as chronic vulvar pain with no clearly identified cause. The announcement signals NIH's continued interest in making vulvodynia a sustained, core area of research and is meant to increase the number and quality of studies that can clarify why the condition occurs, how it can be prevented, how it should be diagnosed, and what treatments work best. A central theme of the opportunity is the encouragement of multidisciplinary and interdisciplinary research, meaning projects are expected to benefit from teams that span multiple fields (for example, gynecology, pain medicine, neurology, immunology, physical therapy, psychology, epidemiology, genetics, and data science) to move the science forward more quickly than single-discipline approaches.

This opportunity uses the NIH R01 mechanism, which is the standard, investigator-initiated research project grant designed to support well-developed, hypothesis-driven (or otherwise strongly justified) research programs. While the source text does not specify a funding cap or number of awards, the emphasis is on supporting substantive research projects that can materially advance understanding of vulvodynia across the full pipeline from causes and risk factors through clinical management and therapeutics. The core research areas highlighted include etiology (identifying biological, neurological, psychological, and/or environmental mechanisms contributing to chronic vulvar pain), prevention (recognizing modifiable risks and early interventions that could reduce incidence or progression), diagnosis (improving measurement, classification, and clinical identification, potentially including biomarkers or better phenotyping), and therapeutics (testing or developing treatments, alone or in combination, and determining which subgroups benefit from which approaches).

Eligibility for applicant organizations is broad, reflecting NIH's intent to draw ideas from many sectors capable of conducting rigorous biomedical and behavioral research. Eligible applicants include various levels of government (state, county, city/township, and special districts), public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, independent school districts, public housing authorities/Indian housing authorities, and Native American tribal governments and tribal organizations (including federally recognized tribes and other eligible tribal entities). The listing is consistent with NIH's general approach of allowing a wide range of research-capable institutions to apply, provided they can meet the scientific, administrative, and compliance requirements of an NIH grant.

Administratively, this is categorized as a discretionary grant in the Health, Income Security and Social Services area, and it is associated with CFDA numbers 93.865 (and also listed with that value in the source). The opportunity was posted on February 18, 2016, with a listed closing date of May 7, 2019. In practical terms, this FOA served as a formal invitation during that period for investigators to submit R01 applications aligned with the stated vulvodynia research priorities, with particular weight placed on projects that integrate multiple disciplines and perspectives to address a complex, poorly understood pain condition that has significant quality-of-life impacts.

FAQs: Multidisciplinary Research in Vulvodynia (R01) (PA-16-102)

What is the Multidisciplinary Research in Vulvodynia (R01) funding opportunity?

It is a National Institutes of Health (NIH) research grant announcement from HHS/NIH titled "Multidisciplinary Research in Vulvodynia (R01)" with funding opportunity number PA-16-102. It supports research on vulvodynia, commonly described as chronic vulvar pain with no clearly identified cause.

What is the main purpose of this NIH announcement?

The purpose is to increase the number and quality of research studies that can clarify why vulvodynia occurs, how it can be prevented, how it should be diagnosed, and what treatments work best. The announcement also signals NIH's intent to keep vulvodynia as a sustained, core area of research.

What is vulvodynia as described in this opportunity?

Vulvodynia is described as chronic vulvar pain with no clearly identified cause.

What research topics does the opportunity prioritize?

The opportunity highlights four core research areas: etiology (causes and mechanisms), prevention (modifiable risks and early interventions), diagnosis (measurement and clinical identification), and therapeutics (treatments and which subgroups benefit).

What types of etiological (cause-and-mechanism) research are relevant here?

Research aimed at identifying biological, neurological, psychological, and/or environmental mechanisms that contribute to chronic vulvar pain is specifically called out as part of the etiology focus.

What kinds of prevention research fit this FOA?

Projects that recognize modifiable risk factors and explore early interventions that could reduce the incidence of vulvodynia or prevent progression are aligned with the prevention emphasis.

What kinds of diagnosis-focused research are encouraged?

The FOA encourages work to improve measurement, classification, and clinical identification of vulvodynia. This may include efforts involving biomarkers or better phenotyping, as noted in the description.

What kinds of therapeutics research are within scope?

The therapeutics scope includes testing or developing treatments, either alone or in combination, and determining which patient subgroups benefit from which approaches.

Does the opportunity encourage multidisciplinary or interdisciplinary teams?

Yes. A central theme is multidisciplinary and interdisciplinary research. The FOA explicitly emphasizes that projects are expected to benefit from teams spanning multiple fields to move the science forward faster than single-discipline approaches.

Which disciplines are mentioned as examples for team composition?

Examples include gynecology, pain medicine, neurology, immunology, physical therapy, psychology, epidemiology, genetics, and data science.

What grant mechanism does this opportunity use?

This opportunity uses the NIH R01 mechanism, which is the standard investigator-initiated research project grant designed to support well-developed, hypothesis-driven (or otherwise strongly justified) research programs.

Is the R01 expected to support substantive projects?

Yes. While the provided information does not list a funding cap or number of awards, it emphasizes supporting substantive research projects that can materially advance understanding of vulvodynia across the pipeline from causes and risk factors through clinical management and therapeutics.

Does the provided information state a funding cap or number of awards?

No. The source information notes that it does not specify a funding cap or the number of awards.

Who can apply for this grant (what organizations are eligible)?

Eligibility is broad. Eligible applicants include various levels of government (state, county, city/township, and special districts), public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, independent school districts, public housing authorities/Indian housing authorities, and Native American tribal governments and tribal organizations (including federally recognized tribes and other eligible tribal entities).

Are nonprofits eligible to apply?

Yes. Both 501(c)(3) nonprofits and non-501(c)(3) nonprofits are listed as eligible applicants.

Are for-profit organizations eligible to apply?

Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed separately as eligible.

Are higher education institutions eligible?

Yes. Both public/state-controlled institutions of higher education and private institutions of higher education are listed as eligible.

Are tribal governments and tribal organizations eligible?

Yes. Native American tribal governments and tribal organizations are listed as eligible, including federally recognized tribes and other eligible tribal entities.

Are government entities eligible to apply?

Yes. The eligibility list includes state governments, county governments, city or township governments, and special district governments.

How is this grant categorized administratively?

It is categorized as a discretionary grant in the Health, Income Security and Social Services area.

What CFDA number is associated with this opportunity?

The opportunity is associated with CFDA number 93.865 (and it is also listed with that value in the provided information).

When was the opportunity posted?

The opportunity was posted on February 18, 2016.

What is the listed closing date?

The listed closing date is May 7, 2019.

What is the overall scientific approach NIH is trying to promote through this FOA?

The FOA promotes integrated, team-based research that combines multiple perspectives and methods to address a complex, poorly understood pain condition with significant quality-of-life impacts, spanning the full research pipeline from underlying causes through clinical management and treatment.

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