Opportunity Information: Apply for PA 16 100
Apply for PA 16 100
- The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Multidisciplinary Research in Vulvodynia (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
- This funding opportunity was created on Feb 18, 2016 and posted on Feb 18, 2016.
- Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Multidisciplinary Research in Vulvodynia (R21) funding opportunity (PA 16-100) is a discretionary NIH grant program administered under HHS-NIH (listed as HHS-NIH11) that targets exploratory, early-stage research on vulvodynia, broadly described as chronic vulvar pain with no clearly identified cause. The central aim of the announcement is to signal NIH's ongoing priority and sustained interest in vulvodynia as a core area of research and to expand the scientific pipeline of new studies that can move the field forward.
This FOA is designed to encourage research applications that investigate vulvodynia across several key domains: etiology (understanding underlying causes and mechanisms), prevention (identifying risk factors and strategies to reduce incidence or progression), diagnosis (improving detection, classification, or objective assessment), and therapeutics (developing or testing treatments and management approaches). The emphasis on exploration is consistent with the R21 mechanism, which is typically used for innovative, high-impact ideas that may be at an earlier stage of development than larger, confirmatory clinical or mechanistic programs. In practical terms, projects responsive to this announcement would often propose novel hypotheses, pilot data generation, proof-of-concept methods, or new measurement tools that can later support more definitive studies.
A defining feature of this opportunity is its strong preference for multidisciplinary and interdisciplinary approaches. NIH is explicitly looking for research teams that combine expertise across fields in ways that are difficult to achieve within a single discipline, reflecting the complexity of chronic pain conditions and the likelihood that progress will require integration of perspectives such as gynecology, pain medicine, neuroscience, immunology, microbiology, genetics, epidemiology, psychology, physical therapy, data science, and health services research. The FOA frames this as a way to accelerate advances and build a more comprehensive understanding of vulvodynia from basic mechanisms through clinical care.
In terms of funding parameters, the listed award ceiling is $200,000 (as provided in the source data), aligning with the smaller, exploratory scale typical of R21 projects. The opportunity falls under the Health, Income Security and Social Services activity category and is associated with CFDA number 93.865. The announcement was created and posted on February 18, 2016, with a closing date of May 7, 2019 (both the original and current closing dates are the same in the provided record). The source data does not specify the expected number of awards.
Eligibility is broad and includes a wide range of domestic organizational types, suggesting NIH intended to attract diverse applicants with relevant capabilities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (outside of higher education); for-profit organizations other than small businesses; small businesses; and other applicants as further clarified in the announcement's eligibility text. This wide eligibility scope supports the FOA's multidisciplinary intent by allowing participation from academic, clinical, nonprofit, and commercial research environments.
Overall, PA 16-100 positions vulvodynia as an important, ongoing NIH research priority and uses the R21 mechanism to stimulate innovative, cross-disciplinary projects that can uncover causes, sharpen diagnostic approaches, inform prevention, and open new paths for treatment of chronic vulvar pain of unknown etiology.
Frequently Asked Questions (FAQs): Multidisciplinary Research in Vulvodynia (R21) - PA 16-100
What is the name of this funding opportunity?
The opportunity is titled Multidisciplinary Research in Vulvodynia (R21) and is identified as PA 16-100.
Which agency administers this grant program?
This is an NIH grant program administered under HHS-NIH (listed as HHS-NIH11).
What research area does this FOA focus on?
The FOA focuses on vulvodynia, broadly described here as chronic vulvar pain with no clearly identified cause.
What is the central aim of the announcement?
The announcement is intended to signal NIH's ongoing priority and sustained interest in vulvodynia research and to expand the scientific pipeline of new studies that can move the field forward.
What grant mechanism is used, and what does it imply about project scope?
The FOA uses the R21 mechanism, which is generally intended for exploratory, early-stage research. It aligns with innovative, potentially high-impact ideas that may be earlier in development than larger, confirmatory programs.
What kinds of research topics are encouraged under this FOA?
The FOA encourages applications investigating vulvodynia across several domains:
- Etiology (understanding underlying causes and mechanisms)
- Prevention (identifying risk factors and strategies to reduce incidence or progression)
- Diagnosis (improving detection, classification, or objective assessment)
- Therapeutics (developing or testing treatments and management approaches)
Is the FOA aimed at exploratory work or fully developed, confirmatory studies?
It is aimed at exploratory work consistent with the R21 mechanism, such as testing novel ideas and approaches that could support more definitive studies later.
What types of project activities does the FOA suggest are responsive?
Projects responsive to this announcement would often include elements like novel hypotheses, pilot data generation, proof-of-concept methods, or new measurement tools intended to enable later, more definitive research.
Is a multidisciplinary approach required or preferred?
A strong preference is stated for multidisciplinary and interdisciplinary approaches, reflecting the complexity of chronic pain conditions and the expectation that progress will require integrated perspectives.
What kinds of disciplines are mentioned as relevant for team composition?
The FOA points to a wide range of potentially relevant disciplines, including:
- Gynecology
- Pain medicine
- Neuroscience
- Immunology
- Microbiology
- Genetics
- Epidemiology
- Psychology
- Physical therapy
- Data science
- Health services research
What is the maximum award amount listed for this opportunity?
The listed award ceiling is $200,000 (as provided in the source data), consistent with the smaller, exploratory scale typical of R21 projects.
What activity category is this opportunity associated with?
The opportunity falls under the Health, Income Security and Social Services activity category.
What is the CFDA number associated with this funding opportunity?
The FOA is associated with CFDA 93.865.
When was the announcement created and posted?
The announcement was created and posted on February 18, 2016.
What is the closing date for this funding opportunity?
The closing date listed in the provided record is May 7, 2019 (noted as both the original and current closing date in the source data).
Does the source data state how many awards NIH expects to make?
No. The source data provided does not specify the expected number of awards.
Who is eligible to apply?
Eligibility is described as broad and includes a wide range of domestic organizational types, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Other Native American tribal organizations
- Public housing authorities / Indian housing authorities
- Nonprofits with 501(c)(3) status (outside of higher education)
- Nonprofits without 501(c)(3) status (outside of higher education)
- For-profit organizations other than small businesses
- Small businesses
- Other applicants as further clarified in the announcement's eligibility text
Why does the FOA have such broad eligibility?
The broad eligibility supports the FOA's emphasis on multidisciplinary research by allowing participation across academic, clinical, nonprofit, and commercial research environments.
What kinds of outcomes does NIH appear to be aiming for through this FOA?
Based on the provided description, NIH is aiming to stimulate innovative projects that can help:
- Uncover causes and mechanisms of vulvodynia
- Improve diagnostic approaches and assessment
- Inform prevention strategies
- Open new paths for treatment and management
Does this FOA position vulvodynia as a one-time priority or an ongoing NIH research priority?
It positions vulvodynia as an important, ongoing NIH research priority, emphasizing sustained interest and continued development of new studies in this area.
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