Opportunity Information: Apply for PAR 12 175
Apply for PAR 12 175
- The National Institutes of Health in the education food and nutrition health income security and social services sector is offering a public funding opportunity titled "Multidisciplinary Studies of HIV/AIDS and Aging (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jul 18, 2012 and posted on Apr 24, 2012.
- Applicants must submit their applications by Apr 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal governments (Federally recognized) Private institutions of higher education Independent school districts City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Multidisciplinary Studies of HIV/AIDS and Aging (R01) opportunity (Funding Opportunity Number PAR-12-175) is a National Institutes of Health (NIH) discretionary grant program that supported research projects examining how HIV intersects with aging. Its core purpose was to encourage multidisciplinary studies focused on HIV infection itself, HIV-associated conditions, HIV treatment issues, and the biobehavioral or social factors that shape HIV/AIDS outcomes when viewed through the lens of aging or specifically within older adult populations. In practice, this meant NIH was looking for proposals that could help explain and address the clinical and real-world challenges faced by people living with HIV as they grow older, as well as the unique prevention, care, and service needs of older adults affected by HIV.
The scientific scope was intentionally broad and cross-cutting. The FOA highlighted interest in research on HIV infection and its downstream complications in older adults, including conditions that co-occur with HIV and may become more common or more complex with age. It also emphasized HIV treatment in the aging context, which can include questions related to long-term antiretroviral therapy, adherence and tolerability as people age, comorbidities and polypharmacy, and other treatment-related concerns that may differ for older individuals compared to younger populations. Just as importantly, the announcement made clear that NIH wanted work that considers biobehavioral and social dimensions of HIV/AIDS and aging, recognizing that factors like mental health, substance use, stigma, social support, socioeconomic conditions, health care access, and service systems can strongly influence outcomes for older adults living with or at risk for HIV.
In terms of the types of studies welcomed, the FOA explicitly encouraged a range of rigorous research approaches. These included clinical and translational research (work that connects clinical observations to mechanisms, care practices, or improved interventions), observational studies (such as cohort or other epidemiologic designs that can clarify patterns, risk factors, and trajectories over time), and intervention studies (testing strategies to prevent HIV, improve health outcomes, enhance engagement in care, or address behavioral and social drivers). The announcement also made clear that projects could be conducted in both domestic and international settings, signaling interest in research that reflects diverse populations, health systems, and epidemic contexts.
Administratively, this was an R01 grant mechanism, meaning it was designed to support substantial, hypothesis-driven research projects typically led by a principal investigator and research team. The opportunity did not require cost sharing or matching funds. NIH posted the FOA on April 24, 2012, with a creation date of July 18, 2012. The original and final closing date listed was April 7, 2015, and the archive date was May 8, 2015, indicating the program announcement is no longer open for applications under that specific FOA.
Eligibility was expansive and reflected NIH’s standard broad inclusion of research-capable organizations. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than higher education institutions), for-profit organizations (including small businesses and other for-profits), and multiple levels of government (state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities). The eligibility language also explicitly included Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized), as well as tribally controlled colleges and universities. In addition, the FOA allowed participation by a wide range of mission-focused institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. International participation was also permitted: non-U.S. entities (foreign institutions) were eligible to apply, non-U.S. components of U.S. organizations could apply, and foreign components as defined by the NIH Grants Policy Statement were allowed.
The program was associated with a large set of CFDA numbers, reflecting its multidisciplinary nature and the likelihood of involvement across multiple NIH Institutes and Centers with interests spanning aging, infectious disease, mental health, substance use, sleep, nursing research, cancer, cardiovascular disease, diabetes and kidney disease, neurology, immunology/microbiology, and related areas. This breadth underscores the reality that HIV and aging research often sits at the intersection of many fields, including chronic disease management, gerontology, behavioral science, and health services research.
For applicants and institutions seeking more detail, NIH provided an additional information link to the full FOA on the NIH Grants Guide website (http://grants.nih.gov/grants/guide/pa-files/PAR-12-175.html). The contact information supplied in the source data directs technical access or linking problems to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the Multidisciplinary Studies of HIV/AIDS and Aging (R01) opportunity (PAR-12-175)?
PAR-12-175 was a National Institutes of Health (NIH) discretionary grant opportunity that used the R01 mechanism to support substantial, hypothesis-driven research projects focused on how HIV intersects with aging. The program encouraged multidisciplinary work spanning biomedical, clinical, behavioral, and social science perspectives related to HIV and older adult populations.
What was the main purpose of this funding opportunity?
The core purpose was to encourage multidisciplinary studies examining HIV infection, HIV-associated conditions, HIV treatment issues, and the biobehavioral and social factors that influence HIV/AIDS outcomes when viewed through the lens of aging or specifically among older adults.
What kinds of HIV-and-aging topics were of interest to NIH under this FOA?
The FOA indicated broad interest in research that helps explain and address clinical and real-world challenges faced by people living with HIV as they grow older, as well as the prevention, care, and service needs of older adults affected by HIV.
Did the FOA focus only on biomedical or clinical research?
No. While clinical and translational research was encouraged, the FOA also highlighted the importance of biobehavioral and social dimensions of HIV/AIDS and aging, including how social and behavioral factors shape outcomes for older adults living with or at risk for HIV.
What biobehavioral and social factors were specifically mentioned as relevant?
The FOA recognized that factors such as mental health, substance use, stigma, social support, socioeconomic conditions, health care access, and service systems can strongly influence outcomes for older adults living with or at risk for HIV.
What does it mean that the scientific scope was "broad and cross-cutting"?
It means the FOA did not restrict applicants to a narrow set of topics or methods. Instead, it invited studies across multiple disciplines and NIH-relevant areas, reflecting that HIV and aging research often intersects with chronic disease management, gerontology, behavioral science, and health services research.
What types of studies were encouraged?
The FOA explicitly encouraged a range of rigorous research approaches, including:
- Clinical and translational research
- Observational studies (for example, cohort or other epidemiologic designs)
- Intervention studies (testing strategies to prevent HIV, improve outcomes, enhance engagement in care, or address behavioral and social drivers)
Were intervention studies allowed under this opportunity?
Yes. The FOA encouraged intervention studies that test strategies to prevent HIV, improve health outcomes, enhance engagement in care, or address behavioral and social drivers relevant to HIV/AIDS and aging.
Were observational or epidemiologic studies allowed?
Yes. The FOA encouraged observational studies, including cohort and other epidemiologic designs that can clarify patterns, risk factors, and trajectories over time.
Did the FOA include interest in HIV treatment issues for older adults?
Yes. The announcement emphasized HIV treatment in the aging context, including potential questions related to long-term antiretroviral therapy, adherence and tolerability as people age, comorbidities and polypharmacy, and other treatment-related concerns that may differ for older individuals compared to younger populations.
Could projects be conducted outside the United States?
Yes. The FOA stated that projects could be conducted in both domestic and international settings, signaling interest in research that reflects diverse populations, health systems, and epidemic contexts.
What grant mechanism did this opportunity use?
This was an R01 funding opportunity. An R01 is intended to support substantial, hypothesis-driven research projects typically led by a principal investigator and research team.
Did this opportunity require cost sharing or matching funds?
No. The FOA stated that it did not require cost sharing or matching funds.
When was PAR-12-175 posted and when did it close?
NIH posted the FOA on April 24, 2012, and it had a creation date of July 18, 2012. The original and final closing date listed was April 7, 2015, and the archive date was May 8, 2015.
Is this FOA still open for applications?
No. Based on the listed final closing date (April 7, 2015) and archive date (May 8, 2015), the program announcement is no longer open for applications under that specific FOA.
What organizations were eligible to apply?
Eligibility was broad and included many types of research-capable organizations, such as public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than higher education institutions), and for-profit organizations (including small businesses and other for-profits).
Were government entities eligible to apply?
Yes. Eligible applicants included multiple levels of government, including state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Were tribal governments and tribal organizations eligible?
Yes. The eligibility language explicitly included Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized), as well as tribally controlled colleges and universities.
Were minority-serving institutions and community-based organizations included in eligibility?
Yes. The FOA explicitly allowed participation by institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, and regional organizations.
Could U.S. territories or possessions apply?
Yes. U.S. territories or possessions were included among eligible applicants.
Could non-U.S. (foreign) institutions apply?
Yes. International participation was permitted. Non-U.S. entities (foreign institutions) were eligible to apply, non-U.S. components of U.S. organizations could apply, and foreign components (as defined by the NIH Grants Policy Statement) were allowed.
Why were many CFDA numbers associated with this program?
The program was associated with a large set of CFDA numbers, reflecting its multidisciplinary nature and the likelihood of involvement across multiple NIH Institutes and Centers with interests spanning areas such as aging, infectious disease, mental health, substance use, sleep, nursing research, cancer, cardiovascular disease, diabetes and kidney disease, neurology, and immunology/microbiology.
Where can someone find the full text of the FOA?
NIH provided a link to the full FOA on the NIH Grants Guide website: http://grants.nih.gov/grants/guide/pa-files/PAR-12-175.html
Who should be contacted for technical access or linking problems related to the FOA information?
The contact information provided for technical access or linking problems was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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