Opportunity Information: Apply for PA 07 233
Apply for PA 07 233
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Multidisciplinary Translational Research in Critical Care (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Feb 23, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education For profit organizations other than small businesses Small businesses Public housing authorities/Indian housing authorities State governments Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments City or township governments.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply.
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Opportunity Summary:
The NIH funding opportunity PA-07-233, titled "Multidisciplinary Translational Research in Critical Care (R01)," is designed to push forward investigator-initiated translational research that can meaningfully improve the science and practice of critical care. The central idea is to encourage research efforts that cut across traditional disciplinary boundaries, bringing together complementary expertise to move discoveries along the pipeline from basic mechanisms to clinically relevant approaches that can be tested, refined, and ultimately used to improve outcomes for critically ill patients. The emphasis on "multidisciplinary" and "translational" signals that NIH is looking for projects that not only ask important questions, but also deliberately connect laboratory, clinical, and other applied perspectives in ways that can accelerate progress in intensive care settings.
This opportunity uses the NIH Research Project Grant (R01) mechanism, which is the standard, highly flexible NIH grant format intended to support a discrete, specified research project proposed by the investigator(s). In practical terms, that means applicants are expected to propose a clear, well-justified research plan with strong preliminary rationale, appropriate methods, and milestones that fit within the scope of an R01. Because it is investigator initiated, the applicant team drives the specific topic and approach, so long as the work fits within the broader theme of translational critical care research and aligns with NIH priorities represented through the participating NIH programs and related CFDA areas.
Funding decisions under this FOA are contingent on two main factors: the availability of appropriated funds at the time awards are made, and the submission of enough high-quality, meritorious applications to justify making awards. The announcement does not promise a set number of awards and instead indicates that awards will depend on the strength of the application pool and the budget landscape. The application timeline is listed as "multiple receipt dates," meaning the program accepted submissions on recurring standard NIH receipt cycles during the period the announcement was active, rather than having a single one-time deadline. The opportunity was originally posted on February 23, 2007, and it was later archived on March 8, 2010, which means it is no longer active today, but the summary still reflects how NIH structured and described the program while it was open.
The funding activity category is listed under "Health," and the included CFDA numbers show the breadth of NIH scientific areas connected to critical care research. These include cardiovascular diseases research (93.837), lung diseases research (93.838), blood diseases and resources research (93.839), extramural research programs in the neurosciences and neurological disorders (93.853), child health and human development extramural research (93.865), and aging research (93.866). Taken together, those categories highlight how critical care intersects with multiple organ systems and patient populations, including pediatric and geriatric critical illness, and conditions involving the heart, lungs, blood, and brain. The breadth of these categories reinforces the multidisciplinary focus and suggests that competitive applications could span diverse clinical syndromes and mechanistic themes, provided the work remains grounded in translational relevance to critical care.
Eligibility for PA-07-233 was broad and included many types of organizations. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including both those with 501(c)(3) status and certain nonprofits without it, other than institutions of higher education), for-profit organizations (including small businesses and other for-profits), and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. The FOA also included tribal organizations and tribal governments, including federally recognized tribal governments, as well as public housing authorities and Indian housing authorities. In addition to domestic applicants, foreign institutions were eligible to apply, and eligible federal government agencies could also apply, which is notable because not all NIH FOAs explicitly allow both foreign and federal applicants. The opportunity also explicitly stated that there was no cost sharing or matching requirement, consistent with typical NIH research grant structures where mandatory matching funds are generally not required.
For applicants looking for the full official wording, requirements, and any additional scope guidance that was in the original announcement, NIH provided a link to the archived program announcement at http://grants.nih.gov/grants/guide/pa-files/PA-07-233.html. The contact information included the NIH Office of Extramural Research (OER) webmaster addresses for technical issues accessing the announcement online or problems linking to the posting, which indicates that programmatic questions would typically be handled through the participating NIH institutes and centers as specified in the full announcement, while the provided contacts were specifically intended for access or web-related difficulties.
FAQs: NIH PA-07-233 - Multidisciplinary Translational Research in Critical Care (R01)
What is NIH PA-07-233?
PA-07-233 is an NIH funding opportunity announcement titled "Multidisciplinary Translational Research in Critical Care (R01)." It was intended to advance investigator-initiated translational research aimed at improving the science and practice of critical care.
What is the goal of this funding opportunity?
The goal was to encourage translational critical care research that can move discoveries from basic mechanisms toward clinically relevant approaches that can be tested, refined, and ultimately used to improve outcomes for critically ill patients.
What does "multidisciplinary translational research" mean in the context of this FOA?
Within this announcement, "multidisciplinary" and "translational" emphasized research that crosses traditional disciplinary boundaries and deliberately connects laboratory, clinical, and other applied perspectives to accelerate progress in intensive care settings.
What funding mechanism does PA-07-233 use?
This opportunity used the NIH Research Project Grant (R01) mechanism, NIH's standard and flexible grant format intended to support a discrete, specified research project proposed by the investigator(s).
What is expected of an application under an R01 mechanism for this opportunity?
Applicants were expected to propose a clear and well-justified research plan with an appropriate preliminary rationale, suitable methods, and milestones that fit within the scope of an R01, while remaining aligned with translational critical care research goals and relevant NIH priorities.
Is PA-07-233 investigator-initiated or topic-prescriptive?
It was investigator-initiated. The applicant team drove the specific topic and approach, as long as the proposed work fit within the broader theme of translational critical care research and aligned with NIH priorities represented through participating NIH programs and related CFDA areas.
What types of scientific areas does this opportunity connect to?
The announcement highlighted that critical care research intersects with multiple organ systems and patient populations, referencing CFDA areas tied to cardiovascular, lung, blood, neuroscience/neurological disorders, child health/human development, and aging research.
Which CFDA numbers were associated with PA-07-233?
The included CFDA numbers were 93.837 (cardiovascular diseases research), 93.838 (lung diseases research), 93.839 (blood diseases and resources research), 93.853 (neurosciences and neurological disorders extramural research), 93.865 (child health and human development extramural research), and 93.866 (aging research).
What is the funding activity category for this opportunity?
The funding activity category was listed as Health.
Were awards guaranteed under PA-07-233?
No. The announcement indicated that awards were contingent on the availability of appropriated funds at the time awards were made and on the submission of enough high-quality, meritorious applications to justify making awards.
Did the FOA specify the number of awards?
No. The announcement did not promise a set number of awards and indicated that awards would depend on the strength of the application pool and the budget landscape.
What did "multiple receipt dates" mean for this opportunity?
"Multiple receipt dates" indicated that the program accepted submissions on recurring standard NIH receipt cycles during the period the announcement was active, rather than having a single one-time deadline.
Is PA-07-233 still open for applications?
No. The opportunity was posted on February 23, 2007 and later archived on March 8, 2010, meaning it is no longer active today.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain nonprofits without 501(c)(3) status, other than institutions of higher education); for-profit organizations (including small businesses and other for-profits); and many government entities.
Which government entities were eligible?
Eligible government entities included state governments, county governments, city or township governments, special district governments, and independent school districts.
Were tribal organizations and tribal governments eligible?
Yes. The FOA included tribal organizations and tribal governments, including federally recognized tribal governments.
Were housing authorities eligible to apply?
Yes. The eligibility list included public housing authorities and Indian housing authorities.
Could foreign institutions apply?
Yes. The opportunity stated that foreign institutions were eligible to apply.
Could federal government agencies apply?
Yes. The opportunity indicated that eligible federal government agencies could also apply, which was notable because not all NIH opportunities explicitly allow both foreign and federal applicants.
Was cost sharing or matching required?
No. The opportunity explicitly stated that there was no cost sharing or matching requirement.
Where can I find the archived official announcement text?
The archived program announcement was available at http://grants.nih.gov/grants/guide/pa-files/PA-07-233.html.
Who was listed as a contact for problems accessing the announcement online?
The contact information provided was for the NIH Office of Extramural Research (OER) webmaster addresses, intended for technical issues accessing the announcement online or problems linking to the posting.
Were the provided contacts meant for programmatic/scientific questions?
The summary indicates the listed contacts were specifically intended for web-access or linking difficulties; programmatic questions would typically be handled through participating NIH institutes and centers as specified in the full announcement.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 07 233) also looked into and applied for these:
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| Collaborative Pediatric Critical Care Research Network (U10) Apply for RFA HD 08 025 Funding Number: RFA HD 08 025 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
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| Enhancing Developmental Biology Research at Undergraduate Institutions Academic Research Enhancement Award (R15) Apply for PAR 09 084 Funding Number: PAR 09 084 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $150,000 |
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