Opportunity Information: Apply for PA 08 053
Apply for PA 08 053
- The National Institutes of Health in the education environment health sector is offering a public funding opportunity titled "Nanoscience and Nanotechnology in Biology and Medicine (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.389 National Center for Research Resources 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Dec 18, 2007.
- Applicants must submit their applications by Jan 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Independent school districts County governments Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
Nanoscience and Nanotechnology in Biology and Medicine (R21) (Funding Opportunity Number PA-08-053) is a National Institutes of Health (NIH) discretionary grant program designed to push forward early-stage, innovative research that applies nanoscience and nanotechnology to major problems in biology and medicine. The core idea is to support projects that explore and exploit the unique behaviors of materials and systems at the nanoscale, roughly 1 to 100 nanometers, where matter can show properties that do not appear at larger scales. Because biological machinery such as proteins, membranes, viruses, and many cellular structures already operate in this size regime, the FOA emphasizes opportunities where controlling materials at the nanoscale can lead to fundamentally new ways to measure, image, diagnose, treat, or manage disease and injury.
The opportunity is framed around a central medical challenge: current tools for diagnosis, therapy, and long-term disease management often lack the precision, sensitivity, or sophistication needed for complex conditions and traumatic injuries. NIH is signaling that nanotechnology can help drive a new generation of medical innovation by enabling bioactive nanoscale structures, devices, processes, and systems. In practical terms, this can include creating nanoscale platforms that interact directly with biological pathways, deliver therapeutics more selectively, improve imaging contrast and resolution, detect biomarkers earlier and at lower concentrations, or provide novel approaches to regenerative medicine and tissue repair. The FOA encourages work that is grounded in an improved understanding of biology at the nanoscale and then uses that understanding to engineer new solutions.
Administratively, this is an R21 mechanism, which is typically used for exploratory or developmental projects where high innovation and early proof-of-concept are expected, rather than fully mature programs. The award ceiling listed is $200,000, and there is no cost sharing or matching requirement. The program was posted on December 18, 2007, with a closing date of January 7, 2011, and an archive date of February 7, 2011, indicating the announcement is historical/archived rather than currently open.
The scope is intentionally broad and spans many NIH mission areas, which is reflected in the wide set of CFDA numbers associated with the FOA. These include, among others, environmental health, oral health, human genome research, hearing and communication disorders, sleep disorders, mental health, alcohol and drug abuse, technology innovations to improve human health, cancer detection/diagnosis/treatment/biology, cardiovascular and lung diseases, blood disorders, arthritis and musculoskeletal conditions, diabetes and digestive and kidney diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, infectious diseases, general biomedical research and training, aging, and vision research. Taken together, that breadth means applicants could propose nanoscale approaches relevant to nearly any disease area, as long as the work is clearly tied to nanoscale science or engineering and aimed at a meaningful biological or medical problem.
Eligibility is also broad. Applicants may include public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), small businesses and other for-profit organizations (other than small businesses are also eligible), state and local governments (including counties, cities/townships, special districts, and independent school districts), public housing authorities/Indian housing authorities, and Native American tribal governments and tribal organizations. The announcement explicitly notes that foreign institutions are eligible to apply, that eligible federal agencies may apply, and that faith-based or community-based organizations may apply as well, expanding participation beyond the typical domestic academic research base.
For applicants seeking the original full announcement and detailed NIH instructions, the FOA points to the NIH grants guide page at http://grants.nih.gov/grants/guide/pa-files/PA-08-053.html. For technical access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): Nanoscience and Nanotechnology in Biology and Medicine (R21) - PA-08-053
What is this funding opportunity?
This opportunity, titled Nanoscience and Nanotechnology in Biology and Medicine (R21) (Funding Opportunity Number PA-08-053), is a National Institutes of Health (NIH) discretionary grant program intended to support early-stage, innovative research that applies nanoscience and nanotechnology to major problems in biology and medicine.
Which grant mechanism does this program use?
The program uses the NIH R21 mechanism, which is typically intended for exploratory or developmental projects where innovation and early proof-of-concept are emphasized rather than fully mature, large-scale research programs.
What kinds of projects is this FOA trying to support?
The FOA is designed to support projects that explore and exploit unique behaviors of materials and systems at the nanoscale to create new approaches for biology and medicine. It highlights opportunities to engineer bioactive nanoscale structures, devices, processes, and systems that can lead to new ways to measure, image, diagnose, treat, or manage disease and injury.
What does "nanoscale" mean in this announcement?
In this FOA, the nanoscale is described as roughly 1 to 100 nanometers. The announcement emphasizes that matter can display properties at this scale that do not appear at larger scales, and that many biological components (such as proteins, membranes, viruses, and cellular structures) already operate in this size regime.
Why is NIH interested in nanotechnology for biology and medicine?
The FOA frames a central challenge: existing tools for diagnosis, therapy, and long-term disease management often lack the precision, sensitivity, or sophistication needed for complex conditions and traumatic injuries. NIH indicates that nanotechnology may enable a new generation of medical innovation by providing new ways to interact with biological pathways and improve measurement, imaging, diagnosis, treatment, and recovery strategies.
What are some example application areas mentioned in the announcement?
Examples described in the FOA include nanoscale platforms that can:
- Interact directly with biological pathways
- Deliver therapeutics more selectively
- Improve imaging contrast and resolution
- Detect biomarkers earlier and at lower concentrations
- Support novel approaches to regenerative medicine and tissue repair
Is the scope limited to specific diseases or NIH institutes?
No. The scope is described as intentionally broad and spans many NIH mission areas, reflected by the wide set of associated CFDA numbers. The FOA suggests that applicants could propose nanoscale approaches relevant to nearly any disease area as long as the work is clearly tied to nanoscale science or engineering and targets an important biological or medical problem.
What are some NIH mission areas indicated by the CFDA coverage?
The FOA references broad coverage across areas such as environmental health, oral health, human genome research, hearing and communication disorders, sleep disorders, mental health, alcohol and drug abuse, technology innovations to improve human health, cancer, cardiovascular and lung diseases, blood disorders, arthritis and musculoskeletal conditions, diabetes and digestive and kidney diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, infectious diseases, general biomedical research and training, aging, and vision research.
What is the maximum award amount?
The award ceiling listed in the FOA is $200,000.
Is cost sharing or matching required?
No. The announcement states that there is no cost sharing or matching requirement.
When was this funding opportunity posted, and what are the key dates?
The FOA was posted on December 18, 2007. It lists a closing date of January 7, 2011 and an archive date of February 7, 2011.
Is this funding opportunity still open?
Based on the provided dates (closing date in 2011 and archive date in 2011), this announcement appears to be historical/archived rather than currently open.
Who is eligible to apply?
Eligibility is broad. The FOA states that applicants may include:
- Public and private institutions of higher education
- Nonprofit organizations (with or without 501(c)(3) status)
- Small businesses
- Other for-profit organizations (including those other than small businesses)
- State and local governments (including counties, cities/townships, special districts, and independent school districts)
- Public housing authorities/Indian housing authorities
- Native American tribal governments and tribal organizations
Are foreign institutions eligible to apply?
Yes. The announcement explicitly notes that foreign institutions are eligible to apply.
Can federal agencies apply?
Yes. The FOA notes that eligible federal agencies may apply.
Are faith-based or community-based organizations allowed to apply?
Yes. The FOA explicitly states that faith-based or community-based organizations may apply.
What is the main scientific emphasis of proposals under this FOA?
The FOA encourages work grounded in an improved understanding of biology at the nanoscale and using that understanding to engineer new nanoscale solutions for meaningful biological or medical problems.
Where can applicants find the original full announcement and detailed instructions?
The FOA points to the NIH grants guide page at: http://grants.nih.gov/grants/guide/pa-files/PA-08-053.html
Who should be contacted for technical access issues related to the announcement?
For technical access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants who have applied for this opportunity (PA 08 053) also looked into and applied for these:
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| Collaborations with National Centers for Biomedical Computing (R01) Apply for PAR 08 184 Funding Number: PAR 08 184 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
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| Global Research Initiative Program, Basic/Biomedical Sciences (R01) Apply for PAR 07 239 Funding Number: PAR 07 239 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
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| Deepwater Horizon Disaster Research Consortia Health Impacts and Community Resiliency (U19) Apply for RFA ES 11 006 Funding Number: RFA ES 11 006 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $1,200,000 |
| Superfund Hazardous Substance Research and Training Program (P42) Apply for RFA ES 10 010 Funding Number: RFA ES 10 010 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Innovative Bioavailability Assays to Assess the Effectiveness of Contaminated Sediment Remediation (R01) Apply for RFA ES 11 005 Funding Number: RFA ES 11 005 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
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