Opportunity Information: Apply for PAR 13 321

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "National Cancer Institute Program Project Applications (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control.
  • This funding opportunity was created on Oct 28, 2014 and posted on Aug 6, 2013.
  • Applicants must submit their applications by Oct 28, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Special district governments Private institutions of higher education For profit organizations other than small businesses State governments County governments Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), offered this Funding Opportunity Announcement (FOA) to support investigator-initiated Program Project (P01) grants under Funding Opportunity Number PAR-13-321. The purpose of the opportunity is to fund multi-project, team-based research programs that are unified by a clearly defined central theme, focus, or overall scientific objective. Rather than supporting a single stand-alone study, the P01 mechanism is meant for coordinated research efforts where multiple related projects work together in a way that creates added value beyond what the same projects would achieve independently.

The scientific scope is intentionally broad and covers essentially the full spectrum of cancer research. Applicants could propose research in cancer biology, cancer treatment, cancer detection and diagnosis, cancer prevention, and cancer control, among other related topics. NCI indicated that many research approaches are appropriate, including basic research (for example, mechanistic studies of tumor biology), translational work (such as moving discoveries toward clinical application), clinical studies (including patient-oriented research where appropriate), and population-based or epidemiologic research (such as studies of cancer risk, screening, outcomes, or disparities). In other words, the FOA is structured to allow diverse research areas and methodologies as long as they are integrated into a coherent program.

A central structural requirement is that each Program Project application must include at least three distinct research projects. These projects must not be a loose collection of independent aims; they need to be linked by a shared overarching theme and designed to complement one another. The P01 format is typically used when scientific questions are interdependent and progress is accelerated by shared intellectual leadership, shared resources, and coordinated planning across projects. While the provided summary does not list required cores or shared-resource components, the emphasis on integration and a common theme reflects the standard expectation for P01 programs: a compelling rationale for why the combined, collaborative structure is necessary to accomplish the overall objective.

The award is a discretionary grant, categorized under education and health-related funding activities, and it aligns with several CFDA program areas: 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), 93.395 (Cancer Treatment Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control). There is no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal matching funds as a condition of the award.

Eligibility was broad across U.S.-based organizational types. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations other than small businesses, small businesses, and multiple levels of government (state, county, city/township, special district governments, independent school districts, and certain housing authorities). The FOA also explicitly recognized a wide range of institution types and community-based entities as eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations.

Foreign eligibility was limited in a way that is common for NIH opportunities of this type. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as the applicant organization. However, non-domestic components of U.S. organizations could participate, and foreign components as defined by the NIH Grants Policy Statement were allowed, which generally means a U.S. applicant could include certain foreign collaborations or sites if they are well-justified and meet NIH policy requirements.

Key dates in the listing indicate it was posted on August 6, 2013, with an original closing date of January 7, 2015. The record also shows administrative dates tied to the listing (creation date October 28, 2014), a current closing date of October 28, 2014, and an archive date of November 27, 2014, indicating the opportunity is no longer active. The full announcement was linked through the NIH Grants Guide (http://grants.nih.gov/grants/guide/pa-files/PAR-13-321.html), and the contact provided for access or technical issues was the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).

FAQs: NCI/NIH Program Project (P01) Grant - PAR-13-321

What is this funding opportunity?

This is a National Cancer Institute (NCI), National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) to support investigator-initiated Program Project (P01) grants under Funding Opportunity Number PAR-13-321.

What is the goal of the P01 mechanism in this FOA?

The goal is to fund multi-project, team-based research programs that are unified by a clearly defined central theme, focus, or overall scientific objective. The P01 is designed for coordinated research efforts where multiple related projects work together in a way that creates added value beyond what the same projects would achieve independently.

How is a P01 different from a single-project grant?

Rather than supporting one stand-alone study, a P01 supports multiple distinct projects that are intentionally integrated. The expectation is that the projects are interdependent or mutually reinforcing and that the coordinated structure (shared leadership, planning, and resources) accelerates progress toward the overall objective.

How broad is the scientific scope for proposed research?

The scientific scope is intentionally broad and spans essentially the full spectrum of cancer research. Examples mentioned include cancer biology, cancer treatment, cancer detection and diagnosis, cancer prevention, and cancer control, among other related topics.

What kinds of research approaches are allowed?

The FOA indicates many approaches are appropriate, including basic research (for example, mechanistic studies of tumor biology), translational research (moving discoveries toward clinical application), clinical studies (including patient-oriented research where appropriate), and population-based or epidemiologic research (such as studies of cancer risk, screening, outcomes, or disparities). The key requirement is that the work is integrated into a coherent program with a shared theme.

How many projects are required in a Program Project (P01) application?

Each Program Project application must include at least three distinct research projects.

Can the projects be independent of each other?

No. The projects cannot be a loose collection of independent aims. They must be linked by a shared overarching theme and designed to complement one another.

What does NCI emphasize about integration across projects?

NCI emphasizes that the P01 format is typically used when scientific questions are interdependent and when progress is accelerated by shared intellectual leadership, shared resources, and coordinated planning across projects.

Are specific cores or shared-resource components required?

The provided summary does not list required cores or shared-resource components. However, it emphasizes integration and a common theme, which reflects standard expectations for P01 programs, including providing a strong rationale for why a combined collaborative structure is necessary to accomplish the overall objective.

What type of award is this?

This is a discretionary grant categorized under education and health-related funding activities.

Which CFDA program areas does this opportunity align with?

The opportunity aligns with several CFDA program areas: 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), 93.395 (Cancer Treatment Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control).

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal matching funds as a condition of the award.

Who is eligible to apply?

Eligibility is broad across U.S.-based organizational types. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations other than small businesses, small businesses, and multiple levels of government (including state, county, city/township, special district governments, independent school districts, and certain housing authorities).

Are minority-serving institutions and community-based organizations eligible?

Yes. The FOA explicitly recognizes a wide range of institution types and community-based entities as eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations.

Are foreign (non-U.S.) institutions eligible to apply as the applicant organization?

No. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as the applicant organization.

Can a U.S. applicant include foreign components or international collaborations?

Yes. Non-domestic components of U.S. organizations could participate, and foreign components as defined by the NIH Grants Policy Statement were allowed. This generally means a U.S. applicant could include certain foreign collaborations or sites if they are well-justified and meet NIH policy requirements.

When was the opportunity posted, and what were the listed closing dates?

The listing indicates the FOA was posted on August 6, 2013, with an original closing date of January 7, 2015. The record also shows administrative dates including a creation date of October 28, 2014, a current closing date of October 28, 2014, and an archive date of November 27, 2014.

Is this funding opportunity still active?

No. Based on the archive date (November 27, 2014) and the listing information, the opportunity is no longer active.

Where can the full announcement be found?

The full announcement was linked through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-13-321.html

Who should be contacted for access or technical issues related to the announcement?

The contact provided for access or technical issues was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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