Opportunity Information: Apply for RFA HD 16 010
Apply for RFA HD 16 010
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "National Centers for Translational Research in Reproduction and Infertility (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 12, 2015 and posted on May 12, 2015.
- Applicants must submit their applications by Nov 12, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,200,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Small businesses Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) State governments County governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The National Centers for Translational Research in Reproduction and Infertility (NCTRI) (P50) funding opportunity (RFA-HD-16-010) was issued by the National Institutes of Health through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), specifically its Fertility and Infertility Branch (FIB). The program is designed to support a small number of highly collaborative research centers focused on reproductive sciences, with a strong emphasis on translational research that connects basic laboratory discoveries to clinical practice and, importantly, brings clinical observations back into the lab for deeper mechanistic study. In practice, the goal is to speed up meaningful progress in understanding and treating infertility and other reproductive health challenges by building centers that deliberately integrate multiple disciplines rather than funding isolated projects.
A central feature of the opportunity is the expectation that each funded center functions as a true hub for multidisciplinary teamwork. These centers are meant to bring together basic scientists and clinical investigators to build cohesive, high-quality translational programs in priority areas of reproduction and infertility. The announcement frames the centers as part of a national network, which signals that awardees are not only expected to run strong internal programs but also to contribute to a broader community of NCTRI sites that collectively improve communication, innovation, and research excellence across the field. The phrase "bidirectional knowledge transfer" is key: the program is not only about taking bench science to the clinic, but also about letting real-world clinical needs and patient findings shape fundamental research questions.
Beyond research output, the FOA explicitly assigns the centers a national service role in workforce development. NICHD describes these centers as resources for training and career development, particularly for early-career scientists who are committing to research careers in reproduction and infertility. This typically implies structured mentoring, hands-on exposure to translational workflows, and opportunities for trainees to engage with both experimental and clinical environments. The broader intent is to strengthen the pipeline of investigators capable of working across the traditional divide between basic research and patient-centered studies.
The opportunity also highlights community outreach and education as a meaningful responsibility of center investigators. Funded teams are expected to participate in activities that raise public awareness and communicate the relevance, implications, and potential benefits of reproductive and infertility research. This emphasis reflects the public health and social importance of fertility and reproductive health topics, and it also suggests that successful centers should be prepared to engage beyond academia, translating complex research into understandable, responsible public-facing information.
From an administrative and funding standpoint, the NCTRI initiative replaces the earlier Specialized Cooperative Centers Program in Reproduction and Infertility Research (SCCPIR) that used the U54 mechanism. Under this FOA, NICHD shifts to the Specialized Research Center (P50) grant mechanism, which is commonly used for center-based programs that include multiple integrated projects and shared resources aimed at a unifying theme. The announcement projected a limited competition with an expected two awards. The estimated total funding was $3.5 million, with an award ceiling of $1.2 million (as listed in the source data). No cost sharing or matching was required, which lowers barriers for eligible institutions that may not have discretionary funds to meet a match requirement.
Eligibility was broad across many U.S.-based organization types, spanning public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), state and local governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, tribal governments and tribal organizations, and for-profit organizations (other than small businesses), as well as small businesses. The FOA also calls out additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American and Native American Pacific Islander-serving institutions (AANAPISIs), among others, and it includes faith-based or community-based organizations and eligible federal agencies. Foreign institutions were not eligible to apply, and non-U.S. components of U.S. organizations were not eligible, although foreign components (as defined by NIH policy) were allowed, which typically means limited, well-justified international elements can be included when they are essential to the project.
Key timing details in the announcement show it was posted May 12, 2015, with an application closing date of November 12, 2015, and an archive date of December 13, 2015. The CFDA number associated with the opportunity was 93.865 (Child Health and Human Development Extramural Research). For applicants or reviewers looking for the original full text and requirements, the funding announcement was hosted on the NIH grants site under the RFA-HD-16-010 listing (the source included a link to the NIH Guide page). For technical issues accessing the announcement, the NIH Office of Extramural Research (OER) webmaster contact was provided.
Taken together, this FOA aimed to fund a small set of high-impact, center-based programs that could serve as national anchors in reproductive and infertility translational research. The expected outcome was not only stronger science and better clinical translation, but also a more connected national research ecosystem, a better-trained next generation of investigators, and clearer, more effective public communication around reproductive health research.
Frequently Asked Questions (FAQs)
What is the NCTRI (P50) funding opportunity?
The National Centers for Translational Research in Reproduction and Infertility (NCTRI) is a center-based research funding opportunity using the NIH Specialized Research Center (P50) mechanism. It supports a small number of highly collaborative research centers focused on reproductive sciences, with a strong emphasis on translational research in reproduction and infertility.
Which NIH institute and program issued this FOA?
This funding opportunity (RFA-HD-16-010) was issued by the National Institutes of Health through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), specifically the Fertility and Infertility Branch (FIB).
What is the main goal of the NCTRI program?
The main goal is to speed progress in understanding and treating infertility and other reproductive health challenges by funding integrated, multidisciplinary research centers that deliberately connect basic laboratory discoveries with clinical practice and also bring clinical observations back to the lab for mechanistic study.
What does "translational" research mean in this FOA?
In this FOA, translational research is described as bidirectional: moving insights from basic science toward clinical application, and also using clinical findings and unmet patient needs to shape and deepen fundamental laboratory research questions.
How are the funded centers expected to operate?
Each funded center is expected to function as a true hub for multidisciplinary teamwork, integrating basic scientists and clinical investigators into cohesive, high-quality translational programs in priority areas related to reproduction and infertility.
Is there an expectation that awardees collaborate with other NCTRI sites?
Yes. The FOA frames the centers as part of a national network. That implies awardees are expected to contribute beyond their own institution by improving communication, innovation, and research excellence across the broader community of NCTRI sites.
How many awards were expected under this opportunity?
The announcement projected a limited competition with an expectation of two awards.
What was the estimated funding amount and the award ceiling?
The estimated total funding was $3.5 million, and the award ceiling was listed as $1.2 million.
Is cost sharing or matching required?
No. The FOA stated that no cost sharing or matching was required.
What grant mechanism does this program use, and what does it typically support?
This program uses the P50 Specialized Research Center mechanism. P50 awards are commonly used for center-based programs that include multiple integrated projects and shared resources organized around a unifying theme.
Did this initiative replace an earlier program?
Yes. The NCTRI initiative replaced the earlier Specialized Cooperative Centers Program in Reproduction and Infertility Research (SCCPIR), which used the U54 mechanism. Under this FOA, NICHD shifted to the P50 mechanism.
Who was eligible to apply?
Eligibility included a wide range of U.S.-based organizations, such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), state and local governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, tribal governments and tribal organizations, for-profit organizations (other than small businesses), and small businesses. The FOA also identified additional eligible categories such as HBCUs, Hispanic-serving institutions, TCCUs, Alaska Native and Native Hawaiian-serving institutions, and AANAPISIs, among others, and included faith-based or community-based organizations and eligible federal agencies.
Are foreign institutions eligible to apply?
No. Foreign institutions were not eligible to apply.
Can a U.S. organization include non-U.S. components?
No. Non-U.S. components of U.S. organizations were not eligible under the FOA.
Are any international elements allowed at all?
Yes, foreign components (as defined by NIH policy) were allowed. This typically refers to limited, well-justified international elements that are essential to the project.
What workforce development or training expectations were included?
The FOA assigns the centers a national service role in workforce development. NICHD describes the centers as resources for training and career development, particularly for early-career scientists pursuing research careers in reproduction and infertility. This implies structured mentoring and exposure to translational workflows across both experimental and clinical environments.
What outreach and education responsibilities were mentioned?
Funded teams were expected to participate in community outreach and education activities that raise public awareness and communicate the relevance, implications, and potential benefits of reproductive and infertility research in a responsible, understandable way.
When was the opportunity posted and when did it close?
The FOA was posted on May 12, 2015. The application closing date was November 12, 2015.
When was the FOA archived?
The archive date listed was December 13, 2015.
What is the CFDA number associated with this opportunity?
The CFDA number associated with this opportunity was 93.865 (Child Health and Human Development Extramural Research).
Where could applicants find the original FOA text?
The funding announcement was hosted on the NIH grants site under the RFA-HD-16-010 listing (via the NIH Guide page referenced in the source information).
Who was the contact for technical issues accessing the announcement?
For technical issues accessing the announcement, the NIH Office of Extramural Research (OER) webmaster contact was provided in the FOA information.
What kinds of outcomes was NICHD aiming for through NCTRI?
The FOA aimed to produce stronger translational science and better clinical translation in reproduction and infertility, while also building a more connected national research ecosystem, strengthening the pipeline of investigators trained to work across basic and clinical research, and improving public communication around reproductive health research.
Browse more opportunities from the same category: Health Income Security and Social Services
Next opportunity: Ocean Freight Reimbursement Program(OFR) FY2015 and FY2016
Previous opportunity: Domestic Nuclear Detection Office Academic Research Initiative (ARI)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA HD 16 010
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA HD 16 010) also looked into and applied for these:
| Funding Opportunity |
|---|
| Non or Minimally Invasive Methods to Measure Biochemical Substances for Neonatal and Perinatal Clinical Care and Research (R41) Apply for RFA HD 16 028 Funding Number: RFA HD 16 028 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Bioengineering Research Partnership (BRP) Non or Minimally Invasive Methods to Measure Biochemical Substances during Neonatal and Perinatal Patient Care and Research (R01) Apply for PAR 15 285 Funding Number: PAR 15 285 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R01) Apply for RFA HD 16 033 Funding Number: RFA HD 16 033 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R21) Apply for RFA HD 16 034 Funding Number: RFA HD 16 034 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Secondary Analysis of Existing Databases in Traumatic Brain Injury to Explore Outcomes Relevant to Medical Rehabilitation (R21) Apply for RFA HD 16 001 Funding Number: RFA HD 16 001 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Neurodevelopmental Assessment of Infants and Children in Resource Limited Settings (R43/R44) Apply for RFA HD 16 024 Funding Number: RFA HD 16 024 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Neurodevelopmental Assessment of Infants and Children in Resource Limited Settings (R41/R42) Apply for RFA HD 16 025 Funding Number: RFA HD 16 025 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Mechanisms of Human Structural Birth Defects (P01) Apply for RFA HD 16 009 Funding Number: RFA HD 16 009 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,000,000 |
| Pelvic Floor Disorders Network Clinical Sites (UG1) Apply for RFA HD 16 012 Funding Number: RFA HD 16 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $180,000 |
| Pelvic Floor Disorders Network Data Coordinating Center (U24) Apply for RFA HD 16 011 Funding Number: RFA HD 16 011 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Biomedical and Behavioral Research Innovations to Ensure Equity (BRITE) in Maternal and Child Health (R15) Apply for PAR 15 319 Funding Number: PAR 15 319 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Tools for Assessment and Improvement of Neurologic Outcomes (R41/R42) Apply for RFA HD 16 006 Funding Number: RFA HD 16 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Tools for Assessment and Improvement of Neurologic Outcomes (R43/R44) Apply for RFA HD 16 007 Funding Number: RFA HD 16 007 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| CAPSTONE Centers for Multidisciplinary Research and Training in Child Abuse and Neglect (P50) Apply for RFA HD 16 002 Funding Number: RFA HD 16 002 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,000,000 |
| Mechanisms of Adverse Drug Effects in Children (R01) Apply for PAR 08 248 Funding Number: PAR 08 248 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Mechanisms of Adverse Drug Reactions in Children (R03) Apply for PAR 08 249 Funding Number: PAR 08 249 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Contextual Approaches to Prevention of Unintended Pregnancy (R01) Apply for PA 09 014 Funding Number: PA 09 014 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Contextual Approaches to Prevention of Unintended Pregnancy (R21) Apply for PA 09 015 Funding Number: PA 09 015 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Innovation in Molecular Imaging Probes (R01) Apply for PAR 09 016 Funding Number: PAR 09 016 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Mechanisms of Human Structural Birth Defects (P01) Apply for PA 07 419 Funding Number: PA 07 419 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA HD 16 010", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.