Opportunity Information: Apply for RFA OH 14 010
Apply for RFA OH 14 010
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "National Mesothelioma Virtual Bank for Translational Research (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.262 Occupational Safety and Health Program.
- This funding opportunity was created on Jun 23, 2014 and posted on Jun 23, 2014.
- Applicants must submit their applications by Jul 31, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,200,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,100,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Institutions/organizations listed in Section III, 1.A. are eligible to apply.
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Opportunity Summary:
The National Mesothelioma Virtual Bank for Translational Research (U24) grant opportunity (Funding Opportunity Number RFA OH 14 010) was a discretionary funding announcement from the Centers for Disease Control and Prevention (CDC), specifically through the National Institute for Occupational Safety and Health (NIOSH). It was designed to fund the continuation of an existing national resource called the National Mesothelioma Virtual Bank for Translational Research (NMVB). In practical terms, this program supports a virtual registry and tissue bank focused on mesothelioma, with the core aim of making high-quality, well-annotated biospecimens and associated data available to qualified investigators who are working on mesothelioma research, including translational studies that connect laboratory findings to clinical or population-level applications.
The funding mechanism was a Cooperative Agreement (U24), which typically indicates that the government expects substantial involvement in the project beyond standard grant oversight. Rather than simply providing funds and receiving annual progress reports, a U24 generally reflects an active partnership model where the agency may coordinate, provide guidance on priorities, and participate in shaping how the resource is maintained, improved, and shared with the research community. The activity category was Health, and the CFDA listing was 93.262 (Occupational Safety and Health Program), aligning with NIOSH's mission because mesothelioma is strongly associated with occupational exposures, most notably asbestos.
NIOSH expected to make a single award under this announcement (ExpectedAwards: 1), emphasizing that the intent was to support one central coordinating effort to continue and manage the NMVB. The estimated total funding amount was $2,200,000, and the award ceiling was $1,100,000, which suggests a likely multi-year project period where the total projected support could span more than one budget year. There was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible or competitive.
The opportunity was posted on June 23, 2014, and the original and final application closing date was July 31, 2014. The listing was archived on August 30, 2014, indicating it is no longer open for applications, but it remains a useful reference for understanding federal priorities and expectations for similar biospecimen and registry infrastructure projects. Eligibility was described broadly as "Others (see text field...)" with further clarification indicating that eligible applicants were the institutions and organizations listed in Section III, 1.A of the full announcement. In other words, eligibility depended on the specific categories enumerated in the complete solicitation document, which applicants would need to consult to confirm whether they qualified.
At its core, the NMVB concept is about research enablement. Mesothelioma is relatively rare, which makes it difficult for individual institutions to accumulate enough cases, tissue samples, and consistent clinical and exposure information to support robust research on their own. A national virtual bank and registry helps solve that problem by pooling resources, standardizing how information is captured, and offering an access pathway for investigators. By supporting the continuation of NMVB, NIOSH aimed to preserve and strengthen an established platform that could accelerate discovery in areas such as biomarkers, molecular characterization, exposure-disease relationships, disease mechanisms, and potential therapeutic targets, while also improving the comparability and reproducibility of studies by providing consistent specimen handling practices and associated source data.
For applicants or interested parties who needed help accessing the full announcement, the notice provided a point of contact: the CDC Procurement and Grants Office (PGO), Technical Information Management Section (TIMS), reachable by phone at 770-488-2700. The Additional Information Link included in the summary was noted as not active, with instructions to use the "full announcement" link on the hosting page to access the complete program details, requirements, and submission instructions.
Frequently Asked Questions (FAQs): National Mesothelioma Virtual Bank for Translational Research (U24) - RFA OH 14 010
What is this grant opportunity?
This was a discretionary federal funding opportunity titled the National Mesothelioma Virtual Bank for Translational Research (U24), Funding Opportunity Number RFA OH 14 010. It was issued by the Centers for Disease Control and Prevention (CDC) through the National Institute for Occupational Safety and Health (NIOSH).
What was the program intended to fund?
The announcement was designed to fund the continuation of an existing national resource called the National Mesothelioma Virtual Bank for Translational Research (NMVB). In practice, it supported a virtual registry and tissue bank focused on mesothelioma, with the goal of making high-quality, well-annotated biospecimens and related data available to qualified investigators.
What is the NMVB (National Mesothelioma Virtual Bank for Translational Research)?
NMVB is described as a national virtual bank and registry for mesothelioma research. It pools biospecimens and associated data from multiple sources so that researchers can access a more robust, standardized set of materials than many single institutions could assemble on their own.
Why is a national virtual bank especially important for mesothelioma research?
Mesothelioma is relatively rare. Because of that, individual institutions may have difficulty collecting enough cases, tissue samples, and consistent clinical and exposure information to support strong studies. A national virtual bank and registry helps address this by pooling resources and standardizing information capture.
What types of research did the NMVB resource support?
Based on the description, the resource was meant to enable mesothelioma research including translational studies that connect laboratory findings to clinical or population-level applications. The summary notes potential use areas such as biomarkers, molecular characterization, exposure-disease relationships, disease mechanisms, and potential therapeutic targets.
What does "well-annotated biospecimens and associated data" mean in this context?
The opportunity emphasizes biospecimens with strong accompanying information, including related data that improves interpretability and supports comparability across studies. The summary also highlights consistent specimen handling practices and associated source data to improve reproducibility.
What was the funding mechanism?
The funding mechanism was a Cooperative Agreement (U24). This mechanism generally reflects a partnership model where the government expects substantial involvement beyond standard oversight.
What does a U24 Cooperative Agreement imply about agency involvement?
The summary explains that, rather than only providing funds and receiving routine progress reports, a U24 typically indicates active involvement from the agency. This can include coordinating, providing guidance on priorities, and participating in shaping how the resource is maintained, improved, and shared with the research community.
Which agency and program area supported this opportunity?
The announcement came from CDC through NIOSH. The activity category was Health, and the CFDA listing was 93.262 (Occupational Safety and Health Program).
Why was this opportunity aligned with occupational safety and health?
NIOSH alignment is explained by the strong association between mesothelioma and occupational exposures, most notably asbestos.
How many awards were expected?
NIOSH expected to make a single award under this announcement (ExpectedAwards: 1), indicating an intent to support one central coordinating effort to continue and manage NMVB.
What was the estimated total funding amount?
The estimated total funding amount was $2,200,000.
What was the award ceiling?
The award ceiling was $1,100,000.
Does the opportunity information suggest a multi-year project?
Yes. The summary notes that the estimated total funding of $2,200,000 and an award ceiling of $1,100,000 suggests a likely multi-year project period where total projected support could span more than one budget year.
Was cost sharing or matching required?
No. The announcement states there was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible or competitive.
When was the opportunity posted?
The opportunity was posted on June 23, 2014.
What were the application due dates?
The original and final application closing date was July 31, 2014.
Is this funding opportunity still open?
No. The listing was archived on August 30, 2014, which indicates it is no longer open for applications.
What does it mean that the listing is archived?
In this context, archived means the funding opportunity is no longer accepting applications. The summary also notes it can still serve as a reference for federal priorities and expectations for similar registry and biospecimen infrastructure projects.
Who was eligible to apply?
Eligibility was described broadly as "Others (see text field...)" with clarification that eligible applicants were the institutions and organizations listed in Section III, 1.A of the full announcement. Applicants would need to consult the complete solicitation document to confirm whether they qualified.
Where could applicants find the full eligibility details?
The summary indicates eligibility depended on the specific categories enumerated in the complete solicitation document, referenced as Section III, 1.A of the full announcement.
How could someone access the full announcement if the additional information link was not working?
The summary notes the Additional Information Link was not active and instructs users to use the "full announcement" link on the hosting page to access complete details, requirements, and submission instructions.
Who could be contacted for help obtaining the full announcement?
The notice provided a contact point: the CDC Procurement and Grants Office (PGO), Technical Information Management Section (TIMS), by phone at 770-488-2700.
What was the central goal of funding the NMVB continuation?
The central aim was research enablement: preserving and strengthening an established platform that provides a standardized pathway for qualified investigators to access biospecimens and associated data for mesothelioma research.
How was the NMVB expected to help study quality and comparability?
The summary states that the resource could improve comparability and reproducibility by providing consistent specimen handling practices and associated source data.
What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number provided is RFA OH 14 010.
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