Opportunity Information: Apply for RFA MH 13 071
Apply for RFA MH 13 071
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "National NeuroAIDS Tissue Consortium (NNTC) Data Coordinating Center (DCC) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Jul 5, 2012 and posted on Jul 5, 2012.
- Applicants must submit their applications by Sep 4, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $600,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses Special district governments Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The National NeuroAIDS Tissue Consortium (NNTC) Data Coordinating Center (DCC) (U24) funding opportunity (RFA-MH-13-071) is a National Institutes of Health cooperative agreement led by the National Institute of Mental Health (NIMH) in partnership with the National Institute of Neurological Disorders and Stroke (NINDS). Its purpose is to fund a single Data Coordinating Center that will serve as the central data and analytics hub for the NNTC, a national resource designed to speed discovery research on HIV-associated diseases of the central nervous system (CNS) and peripheral nervous system (PNS). The NNTC supports investigators by providing access to well-characterized clinical and research data linked to biological specimens, including post-mortem tissues, which are particularly important for understanding neurological complications of HIV.
The DCC is expected to work hand-in-hand with the NNTC Clinical Sites that are funded under a companion announcement (RFA-MH-13-070). The clinical sites handle all direct participant interactions, including all ante-mortem clinical assessments, and they also collect and physically house post-mortem clinical specimens. In contrast, the DCC does not function as a clinical site. Instead, it provides the infrastructure and expertise needed to coordinate consortium-wide operations from a data standpoint, ensuring that the NNTC functions as a unified, high-quality national research resource rather than a set of disconnected site-level databases and specimen inventories.
A core responsibility of the DCC is management and database capability to support effective clinical and brain banking operations across the consortium. Practically, that means building and maintaining systems that can capture standardized clinical assessment data, track operational workflows, and promote consistent data practices across multiple geographically distributed sites. The DCC is also positioned as the central data repository for the consortium. It will store and curate a broad range of information, including ante-mortem clinical assessment data; post-mortem data such as brain pathology reports; laboratory test results generated from collected specimens and fluids; and a comprehensive, site-by-site inventory of what specimens exist, where they are housed, and what metadata are associated with them. In addition, the FOA explicitly anticipates research-oriented datasets (for example, bioinformatics datasets) being incorporated, meaning the DCC must be able to support modern research data types and the governance needed to manage them responsibly.
Another major expectation is that the DCC brings scientific expertise, especially in biostatistics and HIV epidemiology, to enable broad, rigorous analysis of the NNTC clinical database. This includes supporting consortium-wide analyses that leverage the full cohort rather than a single-site subset, and providing post-award statistical support connected to recruitment and retention goals for the NNTC cohort. In other words, the DCC is not just a passive data warehouse; it is expected to be an active scientific partner that helps the consortium measure performance, monitor cohort composition over time, and ensure that the data resource is analytically useful for the larger research community.
From an administrative and funding standpoint, this is a discretionary health research opportunity using a cooperative agreement mechanism (U24), which typically implies substantial NIH programmatic involvement and coordination expectations compared with a standard research grant. NIH anticipated making one award, with an estimated total funding level of $600,000 and an award ceiling of $600,000. There is no cost sharing or matching requirement listed.
Eligibility is broad across U.S.-based organizations and governments. Eligible applicants include many types of nonprofit and for-profit organizations, small businesses, public and private institutions of higher education, and state, county, city/township, and special district governments, as well as tribal governments and tribally controlled institutions. The announcement also lists specific categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations as eligible where applicable. Foreign institutions are not eligible to apply, and the FOA also excludes non-U.S. components of U.S. organizations and foreign components as defined by NIH policy.
Key dates indicate this was posted July 5, 2012, with an original and current closing date of September 4, 2012, and an archive date of October 5, 2012. The program is associated with CFDA numbers 93.242 (Mental Health Research Grants) and 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The full announcement was provided through the NIH grants guide, and NIH’s Office of Extramural Research webmaster contacts were listed for access or linking issues.
Frequently Asked Questions (FAQ)
1. What is this funding opportunity?
This opportunity funds the National NeuroAIDS Tissue Consortium (NNTC) Data Coordinating Center (DCC) under a U24 cooperative agreement. The announcement is RFA-MH-13-071 and is led by the National Institute of Mental Health (NIMH) in partnership with the National Institute of Neurological Disorders and Stroke (NINDS).
2. What is the purpose of the NNTC Data Coordinating Center (DCC)?
The purpose is to support a single, central Data Coordinating Center that serves as the data and analytics hub for the NNTC, helping the consortium function as a unified, high-quality national research resource focused on HIV-associated diseases of the central nervous system (CNS) and peripheral nervous system (PNS).
3. How many awards does NIH expect to make?
NIH anticipated making one award.
4. What is the funding amount for this opportunity?
The estimated total funding level is $600,000, and the award ceiling is $600,000.
5. Is cost sharing or matching required?
No cost sharing or matching requirement is listed.
6. What grant mechanism is used?
This is a cooperative agreement (U24). A cooperative agreement typically involves substantial NIH programmatic involvement and coordination expectations compared with a standard research grant.
7. Which NIH institutes are leading this opportunity?
The opportunity is led by NIMH in partnership with NINDS.
8. What is the NNTC, and what does it provide to investigators?
The NNTC is a national resource intended to speed discovery research on HIV-associated diseases of the CNS and PNS. It supports investigators by providing access to well-characterized clinical and research data linked to biological specimens, including post-mortem tissues used to study neurological complications of HIV.
9. How does the DCC relate to the NNTC Clinical Sites?
The DCC is expected to work closely with the NNTC Clinical Sites funded under a companion announcement (RFA-MH-13-070). Clinical sites handle direct participant interactions, ante-mortem clinical assessments, and collection/physical housing of post-mortem specimens. The DCC does not function as a clinical site and instead coordinates and supports consortium-wide data operations.
10. Does the DCC conduct clinical assessments or interact directly with participants?
No. The DCC does not function as a clinical site. Direct participant interactions and ante-mortem clinical assessments are handled by the NNTC Clinical Sites.
11. Where are post-mortem clinical specimens physically housed?
Post-mortem clinical specimens are collected and physically housed by the NNTC Clinical Sites, not by the DCC.
12. What are the DCC's core responsibilities related to data management?
The DCC is responsible for management and database capabilities that support effective clinical and brain banking operations across the consortium. This includes building and maintaining systems to capture standardized clinical assessment data, track operational workflows, and promote consistent data practices across multiple geographically distributed sites.
13. What types of data is the DCC expected to store and curate?
The DCC will serve as the central data repository and store/curate a broad range of information, including:
- Ante-mortem clinical assessment data
- Post-mortem data (such as brain pathology reports)
- Laboratory test results generated from collected specimens and fluids
- A comprehensive site-by-site specimen inventory (what exists, where it is housed, and associated metadata)
14. Does the opportunity anticipate supporting research-oriented datasets (for example, bioinformatics datasets)?
Yes. The announcement explicitly anticipates that research-oriented datasets, including bioinformatics datasets, may be incorporated. This implies the DCC must be able to support modern research data types and the governance needed to manage them responsibly.
15. Is the DCC only a data warehouse?
No. The DCC is expected to be an active scientific partner, not just a passive data repository.
16. What scientific expertise is the DCC expected to provide?
The DCC is expected to bring scientific expertise, especially in biostatistics and HIV epidemiology, to enable broad and rigorous analysis of the NNTC clinical database.
17. What kinds of analyses is the DCC expected to support?
The DCC is expected to support consortium-wide analyses that leverage the full cohort rather than single-site subsets. It is also expected to provide post-award statistical support connected to recruitment and retention goals for the NNTC cohort.
18. What does "consortium-wide operations from a data standpoint" mean in this context?
It means the DCC provides the infrastructure and expertise to ensure data collection, curation, inventorying, and analysis practices are coordinated across multiple clinical sites so the NNTC operates as an integrated national resource rather than disconnected site-level databases and specimen inventories.
19. Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and governments, including nonprofit and for-profit organizations, small businesses, public and private institutions of higher education, and state/county/city or township/special district governments, as well as tribal governments and tribally controlled institutions. The announcement also lists categories such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations as eligible where applicable.
20. Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply.
21. Are non-U.S. components of U.S. organizations or foreign components allowed?
No. The opportunity excludes non-U.S. components of U.S. organizations and foreign components as defined by NIH policy.
22. What are the key dates for this funding opportunity?
The opportunity was posted July 5, 2012. The original and current closing date is September 4, 2012. The archive date is October 5, 2012.
23. What does it mean that the announcement is archived?
The archive date (October 5, 2012) indicates the announcement is no longer active as a current funding opportunity based on the dates provided.
24. What is the companion announcement for the NNTC Clinical Sites?
The companion announcement for the NNTC Clinical Sites is RFA-MH-13-070.
25. What CFDA numbers are associated with this program?
This program is associated with CFDA 93.242 (Mental Health Research Grants) and CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders).
26. Where was the full announcement made available?
The full announcement was provided through the NIH grants guide.
27. Who was listed for technical issues related to accessing or linking to the announcement?
NIH's Office of Extramural Research webmaster contacts were listed for access or linking issues.
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Previous opportunity: Limited Competition National NeuroAIDS Tissue Consortium (NNTC) Clinical Sites (U24)
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