Opportunity Information: Apply for RFA CA 12 010
Apply for RFA CA 12 010
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "NCI National Clinical Trials Network Network Group Operations Centers (U10)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research.
- This funding opportunity was created on Jul 23, 2012 and posted on Jul 23, 2012.
- Applicants must submit their applications by Jan 15, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $90,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The funding opportunity RFA-CA-12-010, titled "NCI National Clinical Trials Network (NCTN) Network Group Operations Centers (U10)," is a National Institutes of Health (NIH) cooperative agreement intended to support institutions that will serve as the central operational hubs for Network Groups within the National Cancer Institute's (NCI) National Clinical Trials Network. The NCTN is NCI's large-scale, coordinated clinical trials system for cancer, built to design and run state-of-the-art, multi-institutional studies that can definitively test new cancer therapies and related clinical approaches. A major emphasis is on large, practice-changing trials and advanced imaging studies, spanning both adult and pediatric oncology, where collaboration across many sites is essential to enroll enough participants and produce results that can reliably guide clinical care.
This particular FOA focuses on establishing and supporting the "Operations Center" function for an NCTN Network Group. In practical terms, an Operations Center is responsible for the organizational and administrative backbone that keeps a complex national clinical trials portfolio moving. While the announcement text provided does not list every task in detail, Operations Centers in a networked trials environment typically coordinate protocol development and activation workflows, manage communications across participating institutions, support trial oversight and compliance processes, coordinate committee structures and meetings, and serve as a primary interface between the Network Group and NCI. Because the award mechanism is a cooperative agreement (U10), the work is expected to be carried out in close collaboration with NCI program staff, with substantial federal involvement in the coordination and stewardship of the network's activities.
The Operations Centers supported by this FOA are one of six coordinated components that make up the broader NCTN structure, with each component funded through its own separate FOA. The six components named in the opportunity are: (1) Network Group Operations Centers (the focus of this FOA), (2) Network Group Statistics and Data Management Centers, (3) Network Group Integrated Translational Science Support Centers, (4) Lead Academic Participating Site Centers, (5) Network Radiotherapy and Imaging Core Services Centers, and (6) a Canadian Collaborating Clinical Trials Network. The way the opportunity is framed makes it clear that the Operations Center is not meant to function in isolation; it is a key piece of an interdependent system where operational leadership, data and statistics infrastructure, translational science, site participation, and imaging/radiotherapy core support are designed to work together to deliver high-quality national trials efficiently.
From a funding and administrative standpoint, the opportunity is categorized as discretionary funding and uses the cooperative agreement funding instrument. It sits within NIH health-related activity categories and is associated with CFDA numbers 93.394 (Cancer Detection and Diagnosis Research) and 93.395 (Cancer Treatment Research). The estimated total funding amount listed is $90,000,000. The opportunity was posted and created on July 23, 2012, with an original and current closing date of January 15, 2013, and an archive date of February 15, 2013. No cost sharing or matching requirement is indicated, meaning applicants were not expected to provide a formal matching contribution as a condition of award.
Eligibility is broad across the higher education, nonprofit, and private sectors, reflecting the national scope of the network and the need for strong institutional capacity. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), and for-profit organizations (other than small businesses). The announcement also explicitly includes several categories of institutions and organizations that are often highlighted in federal eligibility language, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and regional organizations. At the same time, the FOA states that non-U.S. (foreign) entities are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply; however, "foreign components" as defined in the NIH Grants Policy Statement are allowed, which typically means certain project elements may be carried out abroad under specific NIH rules even though the applicant organization itself must be U.S.-based.
For applicants deciding whether this opportunity fits, the central idea is that NCI was seeking institutions capable of running the operational command center of an NCTN Network Group: an entity with the governance structures, administrative expertise, and coordination capacity to manage a national, multi-site cancer clinical trials agenda in partnership with NCI. The full announcement was made available through the NIH Grants Guide at the link provided (http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-12-010.html). The contact information included points to the NIH Office of Extramural Research (OER) webmaster emails for technical difficulties accessing or linking to the announcement.
Frequently Asked Questions (FAQs)
What is the funding opportunity RFA-CA-12-010?
RFA-CA-12-010 is an NIH cooperative agreement funding opportunity titled "NCI National Clinical Trials Network (NCTN) Network Group Operations Centers (U10)." It is intended to support institutions that will serve as the central operational hubs (Operations Centers) for Network Groups within the National Cancer Institute (NCI) National Clinical Trials Network.
Which agency is offering this opportunity?
This opportunity is offered through the National Institutes of Health (NIH), specifically supporting activities within the National Cancer Institute (NCI).
What is the NCI National Clinical Trials Network (NCTN)?
The NCTN is NCI's large-scale, coordinated clinical trials system for cancer. It is designed to run multi-institutional studies that can definitively test new cancer therapies and related clinical approaches, including large, practice-changing trials and advanced imaging studies.
What types of trials and study areas does the NCTN emphasize?
Based on the description provided, NCTN emphasizes large, practice-changing trials and advanced imaging studies across both adult and pediatric oncology, where collaboration across many sites is needed to enroll enough participants and generate results that can guide clinical care reliably.
What is the main purpose of this FOA?
The FOA focuses on establishing and supporting the Operations Center function for an NCTN Network Group. The Operations Center is positioned as the organizational and administrative backbone that helps keep a complex national clinical trials portfolio moving.
What does an NCTN Network Group Operations Center do?
The provided summary explains that the FOA does not list every task in detail, but it describes typical responsibilities in a networked trials environment. These typically include coordinating protocol development and activation workflows, managing communications across participating institutions, supporting trial oversight and compliance processes, coordinating committee structures and meetings, and serving as a primary interface between the Network Group and NCI.
Is this award a grant or a cooperative agreement?
This opportunity uses the NIH cooperative agreement mechanism (U10). Under a cooperative agreement, the work is expected to be carried out in close collaboration with NCI program staff, with substantial federal involvement in coordination and stewardship of network activities.
What does "U10" mean in this context?
"U10" refers to the NIH cooperative agreement activity code used for this opportunity. The summary indicates it is structured to involve close collaboration with NCI staff and substantial federal involvement, consistent with a cooperative agreement model.
How does the Operations Center fit within the overall NCTN structure?
The Operations Centers supported by this FOA are described as one of six coordinated components that make up the broader NCTN structure. The Operations Center is not meant to operate in isolation; it is part of an interdependent system designed to deliver high-quality national trials efficiently.
What are the six NCTN components mentioned in the opportunity?
The six components listed are: (1) Network Group Operations Centers (this FOA), (2) Network Group Statistics and Data Management Centers, (3) Network Group Integrated Translational Science Support Centers, (4) Lead Academic Participating Site Centers, (5) Network Radiotherapy and Imaging Core Services Centers, and (6) a Canadian Collaborating Clinical Trials Network.
Is each NCTN component funded through this FOA?
No. The summary states that each of the six components is funded through its own separate FOA. This FOA specifically addresses the Network Group Operations Centers component.
What is the estimated total funding amount listed for this opportunity?
The estimated total funding amount listed is $90,000,000.
Is this opportunity discretionary funding?
Yes. The opportunity is categorized as discretionary funding.
Are there specific CFDA numbers associated with this FOA?
Yes. The opportunity is associated with CFDA 93.394 (Cancer Detection and Diagnosis Research) and 93.395 (Cancer Treatment Research).
When was the opportunity posted?
The opportunity was posted and created on July 23, 2012.
What were the closing date and archive date?
The original and current closing date listed is January 15, 2013, and the archive date is February 15, 2013.
Is there a cost sharing or matching requirement?
No cost sharing or matching requirement is indicated. The summary states that applicants were not expected to provide a formal matching contribution as a condition of award.
Who is eligible to apply?
Eligibility is broad across higher education, nonprofit, and private sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), and for-profit organizations (other than small businesses).
Are HBCUs, Hispanic-serving institutions, and Tribal colleges included in eligibility?
Yes. The eligibility language explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and regional organizations.
Can foreign (non-U.S.) organizations apply?
No. The FOA states that non-U.S. (foreign) entities are not eligible to apply.
Can a U.S. organization apply if parts of the organization are outside the U.S.?
The FOA states that non-U.S. components of U.S. organizations are not eligible to apply.
Are any foreign activities allowed under this opportunity?
Yes, with an important distinction. While the applicant organization must be U.S.-based and foreign entities are not eligible to apply, the FOA indicates that "foreign components" (as defined in the NIH Grants Policy Statement) are allowed, which typically means certain project elements may be carried out abroad under NIH rules.
What kind of institution is this opportunity really aimed at?
Based on the description provided, it is aimed at institutions capable of serving as the operational command center for an NCTN Network Group, with the governance structures, administrative expertise, and coordination capacity to manage a national, multi-site cancer clinical trials agenda in partnership with NCI.
Where can applicants find the full announcement text?
The full announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-12-010.html
Who should be contacted for technical issues accessing the announcement?
The contact information provided points to NIH Office of Extramural Research (OER) webmaster email contacts for technical difficulties accessing or linking to the announcement.
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