Opportunity Information: Apply for PAR 14 096
Apply for PAR 14 096
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NEI Collaborative Clinical Vision Research Project Grant (U10)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.867 Vision Research.
- This funding opportunity was created on Feb 12, 2014 and posted on Feb 12, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments Independent school districts Small businesses Native American tribal governments (Federally recognized) State governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses County governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NEI Collaborative Clinical Vision Research Project Grant (U10) (Funding Opportunity Number PAR-14-096) was a National Institutes of Health cooperative agreement program run by the National Eye Institute to support investigator-initiated clinical vision research. The central aim of the opportunity was to enable large-scale, complex, multi-center efforts that go beyond what a single site or a simpler grant structure can reasonably manage. It was geared toward clinical trials as well as other types of clinical vision studies that may be operationally complicated, resource-intensive, or higher risk, where strong coordination and shared infrastructure are essential for success. Because it uses a cooperative agreement mechanism, the award structure anticipates substantial NIH/NEI involvement in the conduct and oversight of the project compared with a standard research grant.
The funding instrument type was a cooperative agreement under the health activity category, aligned with CFDA 93.867 (Vision Research). The announcement explicitly emphasized collaborative, multi-component project organization. Applications were expected to be built around several required components: an Overall component that lays out the full scientific and operational plan for the clinical vision research program; a Coordinating Center component to manage core trial/study operations such as protocol implementation, data coordination, quality control, study monitoring, and consistent procedures across sites; a Chair Admin component to support the administrative and leadership functions typically associated with overall study direction, governance, and decision-making; and an Enrollment Center component focused on participant recruitment and enrollment operations. The FOA also allowed optional Resource Centers, which could be proposed when specialized, centralized capabilities were needed (for example, a reading center, imaging core, laboratory core, outcomes assessment center, or other shared resources that improve standardization and efficiency across the network).
A key practical point is that this opportunity was broad in who could apply and was not limited to a narrow class of academic institutions. Eligible applicants included many types of U.S. governmental entities (state, county, city or township, special district governments, public housing authorities/Indian housing authorities), public and private institutions of higher education, independent school districts, nonprofits (including those with and without 501(c)(3) status, other than institutions of higher education), and for-profit organizations (including small businesses and other for-profits). It also extended eligibility to a wide set of mission-driven and serving institutions and organizations, including Historically Black Colleges and Universities, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions. Faith-based and community-based organizations were included, and notably, non-U.S. entities and foreign institutions were eligible to apply, with foreign components allowed consistent with NIH policy.
There was no cost sharing or matching requirement, which means applicants were not required to contribute a defined portion of project costs from non-federal sources as a condition of award. The opportunity was posted on February 12, 2014, and it had an original and current closing date listed as May 7, 2017, with an archive date of June 7, 2017, indicating it is no longer active for new submissions under that specific announcement.
In terms of what NEI was trying to accomplish with this U10 structure, the design reflects the realities of clinical vision research where consistent methods across sites, careful participant enrollment practices, centralized data and quality management, and shared specialized resources often determine whether a study can produce reliable, generalizable results. By encouraging a component-based application (Overall, Coordinating Center, Chair Admin, Enrollment Center, and optional Resource Centers), the FOA signaled that reviewers would expect a clear governance and operational blueprint, well-defined responsibilities, and an infrastructure capable of executing a multi-site clinical study with high fidelity. For full details, applicants were directed to the NIH guide page for PAR-14-096, and technical access questions were routed to the NIH Office of Extramural Research webmaster contacts listed in the notice.
FAQs: NEI Collaborative Clinical Vision Research Project Grant (U10) (PAR-14-096)
What is the NEI Collaborative Clinical Vision Research Project Grant (U10)?
It was a National Institutes of Health (NIH) cooperative agreement funding opportunity run by the National Eye Institute (NEI) to support investigator-initiated clinical vision research through large-scale, collaborative, multi-center projects.
What was the main goal of this funding opportunity?
The central aim was to enable complex, multi-site clinical vision research efforts that are difficult to run under a single-site approach or a simpler grant structure. The focus was on studies that are operationally complicated, resource-intensive, or higher risk and benefit from strong coordination and shared infrastructure.
What types of studies were intended to be supported?
The opportunity was geared toward clinical trials as well as other types of clinical vision studies, particularly when they require robust multi-center coordination, consistent procedures, centralized oversight, and shared resources.
What does it mean that this award used a cooperative agreement (U10) mechanism?
A cooperative agreement anticipates substantial NIH/NEI involvement in the conduct and oversight of the project compared with a standard research grant. The structure is designed for projects where close collaboration with the agency is expected during execution.
Which NIH institute administered this program?
The program was run by the National Eye Institute (NEI) under the National Institutes of Health (NIH).
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number was PAR-14-096.
What was the activity category and program alignment (CFDA) for this opportunity?
It was a health-related cooperative agreement aligned with CFDA 93.867 (Vision Research).
Was this opportunity focused on collaboration and multi-center organization?
Yes. The announcement explicitly emphasized collaborative, multi-component organization and was designed around network-style execution with shared infrastructure across participating sites.
What components were required in the application?
Applications were expected to include several required components:
- Overall component: the full scientific and operational plan for the clinical vision research program.
- Coordinating Center component: management of core operations such as protocol implementation, data coordination, quality control, study monitoring, and consistent procedures across sites.
- Chair Admin component: administrative and leadership functions related to overall study direction, governance, and decision-making.
- Enrollment Center component: participant recruitment and enrollment operations.
What did the Overall component need to cover?
The Overall component was expected to lay out the complete scientific and operational plan for the program, describing how the clinical vision research would be conducted across multiple centers and how the full effort would be managed.
What responsibilities were associated with the Coordinating Center component?
The Coordinating Center was intended to manage core trial or study operations, including protocol implementation, data coordination, quality control, study monitoring, and ensuring consistent procedures across participating sites.
What was the purpose of the Chair Admin component?
The Chair Admin component was meant to support administrative and leadership functions typically tied to overall study direction, governance, and decision-making for the collaborative project.
What was the purpose of the Enrollment Center component?
The Enrollment Center component focused on participant recruitment and enrollment operations, supporting the practical work of bringing eligible participants into the study across sites.
Were any additional components allowed beyond the required ones?
Yes. The FOA allowed optional Resource Centers when specialized, centralized capabilities were needed to improve standardization and efficiency across the network.
What are examples of optional Resource Centers mentioned in the announcement?
Examples included a reading center, imaging core, laboratory core, outcomes assessment center, or other shared resources that help standardize methods and improve efficiency across participating sites.
Who was eligible to apply?
Eligibility was broad and not limited to a narrow set of academic institutions. Eligible applicants included U.S. governmental entities, public and private institutions of higher education, independent school districts, nonprofits (including those with and without 501(c)(3) status, other than institutions of higher education), and for-profit organizations (including small businesses and other for-profits).
Which U.S. government entities were listed as eligible?
The announcement listed multiple types, including state governments, county governments, city or township governments, special district governments, and public housing authorities/Indian housing authorities.
Were minority-serving and mission-driven institutions included in eligibility?
Yes. The eligibility list included Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions.
Were faith-based and community-based organizations eligible to apply?
Yes. Faith-based and community-based organizations were included among eligible applicants.
Could for-profit organizations apply?
Yes. For-profit organizations, including small businesses and other for-profits, were eligible to apply.
Were non-U.S. entities or foreign institutions eligible?
Yes. Non-U.S. entities and foreign institutions were eligible to apply, and foreign components were allowed consistent with NIH policy.
Was cost sharing or matching required?
No. The opportunity stated there was no cost sharing or matching requirement, meaning applicants were not required to contribute a defined portion of costs from non-federal sources as a condition of award.
When was this funding opportunity posted?
It was posted on February 12, 2014.
What was the closing date for submissions under this specific announcement?
The original and current closing date listed was May 7, 2017.
Is PAR-14-096 still active?
No. The archive date was June 7, 2017, indicating it is no longer active for new submissions under that specific announcement.
Why did NEI structure this opportunity around multiple components and shared infrastructure?
The U10 structure reflects the practical needs of clinical vision research, where consistent methods across sites, strong enrollment practices, centralized data and quality management, and shared specialized resources often determine whether results are reliable and generalizable.
What would reviewers likely expect in a strong application under this FOA?
Based on the FOA design, reviewers would expect a clear governance and operational blueprint, well-defined responsibilities across components, and an infrastructure capable of executing a multi-site clinical study with high fidelity and consistent procedures.
Where were applicants directed for full details about the opportunity?
Applicants were directed to the NIH guide page for PAR-14-096 for full details.
Where were technical access questions routed?
Technical access questions were routed to the NIH Office of Extramural Research webmaster contacts listed in the notice.
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