Opportunity Information: Apply for PAR 06 326

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NEI Research Grant for Secondary Data Analysis (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.867 Vision Research.
  • This funding opportunity was created on Dec 5, 2008 and posted on Apr 6, 2006.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Private institutions of higher education Independent school districts County governments Native American tribal governments (Federally recognized) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply.
Apply for PAR 06 326

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Opportunity Summary:

The NEI Research Grant for Secondary Data Analysis (R21) is a National Institutes of Health funding opportunity from the National Eye Institute that supports exploratory, developmental research projects that rely on analyzing data that already exist. Rather than funding new data collection, this program is meant to help investigators make strong scientific use of established database resources, such as previously completed studies, registries, repositories, and other curated datasets relevant to vision and eye-health research (CFDA 93.867, Vision Research). A key requirement is that the proposed analyses can be related to the original study that generated the dataset, but they must be clearly distinct from the original data collection aims, meaning applicants need to show that they are not simply repeating the original project goals but instead asking new, meritorious questions that can be answered with the available data.

This opportunity uses the NIH Exploratory/Developmental Research Grant Award (R21) mechanism, which is generally intended for early-stage or higher-risk concepts where a limited amount of time and funding can yield meaningful progress or proof-of-concept results. Because secondary data analysis projects can range widely in complexity, the program anticipates that individual awards may differ in size and scope. At the same time, the announcement sets firm boundaries on project length and budget: the total project period cannot exceed two years, total direct costs are capped at 275,000 across the two-year period, and no more than 200,000 in direct costs may be requested in any single year. There is no cost sharing or matching requirement.

Eligibility is broad and inclusive. A wide range of organization types may apply, including for-profit and nonprofit entities; public and private institutions such as universities, colleges, hospitals, and laboratories; units of state and local government; federally recognized tribal governments and other tribal entities; eligible federal agencies; and domestic as well as foreign institutions. The eligible applicant list also explicitly includes several government and education-related entities (for example, independent school districts, county governments, city or township governments, special district governments, and public housing authorities/Indian housing authorities), as well as nonprofits with or without 501(c)(3) status. In terms of who may serve as Project Director/Principal Investigator, any individual with the expertise, knowledge, and resources to carry out the work is eligible, and NIH specifically encourages applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities.

Administratively, this is a discretionary grant opportunity with multiple receipt dates rather than a single deadline, and applicants are directed to the full announcement for the specific schedule and submission details. The funding opportunity number is PAR-06-326, and the full program announcement is available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-06-326.html. For access or technical issues related to the announcement, the NIH Office of Extramural Research webmaster is listed as the point of contact.

Frequently Asked Questions (FAQ): NEI Research Grant for Secondary Data Analysis (R21)

What is the NEI Research Grant for Secondary Data Analysis (R21)?

The NEI Research Grant for Secondary Data Analysis (R21) is a National Institutes of Health (NIH) funding opportunity offered through the National Eye Institute (NEI). It supports exploratory and developmental research projects that focus on analyzing data that already exist, rather than collecting new data.

What kind of research does this opportunity support?

This opportunity supports secondary data analysis projects that make strong scientific use of established data resources relevant to vision and eye-health research. Examples of eligible data sources mentioned include previously completed studies, registries, repositories, and other curated datasets.

Does this grant fund new data collection?

No. This program is intended to support analysis of existing datasets and does not focus on funding new data collection.

What is the key requirement for using an existing dataset?

A key requirement is that the proposed analyses must be able to be related to the original study that generated the dataset, but they must be clearly distinct from the original data collection aims. Applicants must show they are not simply repeating the original project goals and are instead addressing new, meritorious research questions that can be answered using the available data.

What funding mechanism is used for this program?

The opportunity uses the NIH Exploratory/Developmental Research Grant Award (R21) mechanism.

Why is the R21 mechanism used here?

The R21 mechanism is generally intended for exploratory, developmental, early-stage, or higher-risk concepts where a limited amount of time and funding can still yield meaningful progress or proof-of-concept results. The program notes that secondary data analysis projects can vary widely in complexity, so award size and scope may differ between projects within the stated limits.

What is the maximum project period?

The total project period cannot exceed two years.

What is the budget limit for this grant?

Total direct costs are capped at $275,000 across the two-year project period.

Is there a limit on how much can be requested per year?

Yes. No more than $200,000 in direct costs may be requested in any single year.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad. A wide range of organization types may apply, including for-profit and nonprofit entities; public and private institutions such as universities, colleges, hospitals, and laboratories; units of state and local government; federally recognized tribal governments and other tribal entities; eligible federal agencies; and domestic as well as foreign institutions.

Are nonprofit organizations eligible even if they do not have 501(c)(3) status?

Yes. The eligible applicant list explicitly includes nonprofits with or without 501(c)(3) status.

Are local government entities eligible (such as school districts or county governments)?

Yes. The eligible applicant list explicitly includes several government and education-related entities, including independent school districts, county governments, city or township governments, special district governments, and public housing authorities/Indian housing authorities.

Are foreign institutions eligible?

Yes. The eligibility description includes domestic as well as foreign institutions.

Who can serve as the Project Director/Principal Investigator (PD/PI)?

Any individual with the expertise, knowledge, and resources to carry out the proposed work is eligible to serve as the PD/PI.

Does NIH encourage applications from underrepresented groups?

Yes. NIH specifically encourages applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities.

Is this a discretionary grant opportunity?

Yes. This is described as a discretionary grant opportunity.

Is there a single deadline to apply?

No. The opportunity is described as having multiple receipt dates rather than a single deadline. Applicants are directed to the full announcement for the specific schedule and submission details.

What is the funding opportunity number?

The funding opportunity number is PAR-06-326.

Where can applicants find the full program announcement?

The full program announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-06-326.html

What is the CFDA number and program area listed for this opportunity?

The opportunity references CFDA 93.867 and identifies the program area as Vision Research.

Who is listed as the point of contact for access or technical issues with the announcement?

For access or technical issues related to the announcement, the NIH Office of Extramural Research webmaster is listed as the point of contact.

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