Opportunity Information: Apply for PAR 09 252

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NEI Research Grant for Secondary Data Analysis (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.867 Vision Research.
  • This funding opportunity was created on Aug 13, 2009 and posted on Aug 13, 2009.
  • Applicants must submit their applications by Sep 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Small businesses Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for PAR 09 252

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Opportunity Summary:

The NEI Research Grant for Secondary Data Analysis (R21) is a National Institutes of Health funding opportunity from the National Eye Institute designed to support exploratory, early-stage research that relies on analyzing data that already exist rather than collecting new data. The central idea is to help investigators take advantage of the large, information-rich datasets produced by prior clinical trials and large-scale epidemiologic studies, especially those supported by NEI, to answer new research questions in vision and eye health in a cost-effective way. Proposals are allowed to be connected to the parent study that generated the dataset, but they must clearly pursue aims that are distinct from the original objectives that justified collecting the data in the first place.

A key emphasis of the program is the value of secondary analyses for generating new insights without the time and expense of launching an entirely new data-collection effort. NEI notes that its funded portfolio often involves intensive, multi-faceted data collection to meet primary study goals, and that those efforts typically produce a "wealth of data" that can support additional hypothesis testing, subgroup analyses, novel outcome modeling, or other investigations that were not part of the initial research plan. While the announcement states that datasets do not have to come exclusively from NEI-funded projects, it also makes clear that NEI-supported data resources are of the highest programmatic interest, meaning applicants strengthen their alignment by using NEI-relevant datasets and framing the work in terms of NEI priorities.

The grant uses the NIH Exploratory/Developmental Research Grant (R21) mechanism, which is intended for innovative, early or proof-of-concept work that can open up new directions. Within this opportunity, an R21 can be used in two broad ways: first, to test hypotheses using existing datasets (for example, evaluating associations, risk factors, outcomes, or treatment effects using previously collected trial or population data), and second, to develop or apply new statistical or analytical methodologies suited to vision research datasets. Applicants are encouraged to position their proposed analyses in relation to NEI programs and priorities, specifically referencing the National Plan for Eye and Vision Research (available on the NEI website) to demonstrate relevance and fit.

Funding is competitive and depends on both the availability of appropriated funds and the number and quality of applications received. The listed award ceiling is $200,000. The opportunity is categorized as a discretionary grant in the health area (CFDA 93.867, Vision Research) and does not require cost sharing or matching.

Eligibility is broad and includes many types of institutions and organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, small businesses, nonprofits with and without 501(c)(3) status (with specific notes in the solicitation), and additional eligible organizations such as Historically Black Colleges and Universities, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, eligible federal agencies, and even non-U.S. entities (foreign organizations). This wide eligibility reflects the program goal of encouraging diverse groups with the expertise to conduct rigorous secondary analyses on existing data resources relevant to eye and vision research.

For reference, the funding opportunity number is PAR-09-252, it was posted on August 13, 2009, and the original/current closing date listed in the archived record is September 7, 2012 (with an archive date of October 8, 2012). The full announcement was hosted through the NIH grants guide, and the notice provides NIH Office of Extramural Research webmaster contacts for technical access issues.

NEI Research Grant for Secondary Data Analysis (R21) (PAR-09-252) FAQs

What is the NEI Research Grant for Secondary Data Analysis (R21)?

It is a National Institutes of Health (NIH) funding opportunity from the National Eye Institute (NEI) that supports exploratory, early-stage research based on analyzing data that already exist, rather than collecting new data. The goal is to help investigators use large, information-rich datasets from prior clinical trials and large-scale epidemiologic studies to answer new vision and eye health research questions in a cost-effective way.

What does "secondary data analysis" mean in this program?

Secondary data analysis means the proposed research relies on datasets that were previously collected for other purposes (for example, a completed clinical trial or epidemiologic study) and uses those data to pursue new analyses, new hypotheses, or new modeling approaches that were not part of the original study plan.

Is this opportunity focused on collecting new data?

No. The central idea of this opportunity is to generate new insights by analyzing existing data, avoiding the time and expense of launching a new data-collection effort.

What types of datasets are especially relevant?

The opportunity emphasizes large, information-rich datasets produced by prior clinical trials and large-scale epidemiologic studies, particularly those supported by NEI. While datasets do not have to come exclusively from NEI-funded projects, NEI-supported data resources are described as being of the highest programmatic interest.

Do datasets have to come from NEI-funded studies?

No. The announcement indicates datasets do not have to be exclusively from NEI-funded projects. However, applications are better aligned when they use NEI-relevant datasets and frame the work in terms of NEI priorities.

Can a proposal be connected to the original (parent) study that generated the data?

Yes. Proposals are allowed to be connected to the parent study that generated the dataset, but the application must clearly pursue aims that are distinct from the original objectives that justified collecting the data in the first place.

What kinds of research activities does this R21 support?

Within this opportunity, the R21 can be used in two broad ways: (1) to test hypotheses using existing datasets (such as examining associations, risk factors, outcomes, or treatment effects using previously collected trial or population data), and (2) to develop or apply new statistical or analytical methodologies suited to vision research datasets.

What is the funding mechanism used for this opportunity?

This opportunity uses the NIH Exploratory/Developmental Research Grant (R21) mechanism, which is intended to support innovative, early-stage, or proof-of-concept work that can open up new research directions.

How should applicants demonstrate relevance to NEI priorities?

Applicants are encouraged to position the proposed analyses in relation to NEI programs and priorities and to specifically reference the National Plan for Eye and Vision Research (available on the NEI website) to show relevance and fit.

What is the maximum award amount (award ceiling)?

The listed award ceiling is $200,000.

Is funding guaranteed if an application is submitted?

No. Funding is competitive and depends on the availability of appropriated funds as well as the number and quality of applications received.

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching.

What is the CFDA number and program area for this opportunity?

The opportunity is listed under CFDA 93.867 (Vision Research) and is categorized as a discretionary grant in the health area.

Who is eligible to apply?

Eligibility is broad and includes many types of institutions and organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, small businesses, nonprofits with and without 501(c)(3) status (with specific notes in the solicitation), and a range of other eligible organizations.

Are minority-serving institutions included as eligible applicants?

Yes. The eligible organization types listed include Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities, and Alaska Native and Native Hawaiian Serving Institutions.

Can faith-based or community-based organizations apply?

Yes. Faith-based or community-based organizations are included among the listed eligible applicants.

Can federal agencies apply?

Yes. Eligible federal agencies are included among the listed eligible applicants.

Are non-U.S. (foreign) organizations eligible?

Yes. The eligibility list explicitly includes non-U.S. entities (foreign organizations).

What is the funding opportunity number for this program?

The funding opportunity number is PAR-09-252.

When was the opportunity posted?

The opportunity was posted on August 13, 2009.

What is the closing date shown in the archived record?

The original/current closing date listed in the archived record is September 7, 2012.

Is this opportunity archived?

Yes. The archived record includes an archive date of October 8, 2012.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guide.

Who is listed for technical or access issues?

The notice provides NIH Office of Extramural Research webmaster contacts for technical access issues.

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