Opportunity Information: Apply for RFA EY 10 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NEI Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) for Statistical Genetics and Genome Informatics" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.867 Vision Research.
  • This funding opportunity was created on Jan 27, 2010 and posted on Jan 27, 2010.
  • Applicants must submit their applications by May 18, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for RFA EY 10 001

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Opportunity Summary:

The NEI Ruth L. Kirschstein NRSA Institutional Research Training Grant (T32) for Statistical Genetics and Genome Informatics (Funding Opportunity Number RFA-EY-10-001) is a National Institutes of Health training grant opportunity from the National Eye Institute (NEI) focused on building institutional training programs in genomic medicine, computational genomics, and statistical genetics as they apply to vision research. The core intent is not to fund a single research project, but to help universities and similar institutions create structured, high-quality training environments that prepare the next generation of scientists to work at the intersection of genetics, data science, and ophthalmology.

At a practical level, the program is meant to support both predoctoral and postdoctoral trainees who are developing specialized skills in ophthalmic statistical genetics and bioinformatics. The underlying scientific goal is to strengthen the workforce capable of identifying genes, genetic variants, and genomic mechanisms that contribute to ocular diseases. NEI frames this as a growing need across basic, clinical, and translational ophthalmic research, where modern genetics and large-scale genomic data require investigators who can handle complex datasets, apply rigorous statistical methods, and use advanced computational approaches to extract meaningful biological and clinical insights.

A major emphasis of the announcement is career development for early-stage researchers. The training program is designed to attract individuals early in their careers, expand their knowledge of the genetics of eye disorders, and encourage them to pursue long-term research careers in statistical genetics, genome informatics, and related areas. In other words, the training is intended to be a pipeline-building effort: institutions build the program, and the program develops trainees who can later become independent investigators addressing eye disease through genomics and quantitative methods.

The funding mechanism is the NIH Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (T32). Under the T32 structure, the award is made to an institution (not directly to an individual trainee), and the institution is responsible for selecting trainees and overseeing their appointments and training experiences. NEI also highlights that trainee recruitment and selection should be conducted in a way that includes recruitment of individuals from diverse backgrounds, reinforcing the expectation that programs broaden participation while building technical and scientific expertise.

In terms of funding expectations, NEI noted that the size and duration of each award could vary because training programs differ in scope and design. While NEI anticipated funding about four applications, the actual number of awards would depend on the availability of funds and the submission of a sufficient number of high-quality, competitive applications. The opportunity is listed as a discretionary grant in the health category (CFDA 93.867, Vision Research) and does not require cost sharing or matching.

Eligibility is oriented toward institutions of higher education and related organizations capable of running an institutional training program. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, along with additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and others as clarified in the full announcement. The posting date was January 27, 2010, and the original and current closing date listed is May 18, 2012, with an archive date of June 18, 2012, indicating the announcement is historical rather than currently open.

Overall, this opportunity reflects NEI’s longer-term commitment to expanding capacity in statistical genetics and genome informatics for vision research by funding institutions to create comprehensive, well-mentored training programs that produce researchers ready to tackle the genetic and computational challenges of ocular disease discovery and translation.

Frequently Asked Questions (FAQs)

What is this grant opportunity?

This opportunity is the NEI Ruth L. Kirschstein NRSA Institutional Research Training Grant (T32) for Statistical Genetics and Genome Informatics. It is a National Institutes of Health (NIH) training grant administered by the National Eye Institute (NEI) under Funding Opportunity Number RFA-EY-10-001.

What is the main purpose of this T32 program?

The purpose is to fund institutional training programs (not single research projects) that build structured, high-quality training environments in genomic medicine, computational genomics, and statistical genetics as they apply to vision research. The intent is to prepare the next generation of scientists working at the intersection of genetics, data science, and ophthalmology.

Is this grant meant to fund a specific research project?

No. NEI emphasizes that the core intent is not to fund one standalone research project, but to support institutions in creating comprehensive training programs that develop trainees and strengthen the future workforce in this area.

Which NIH/Institute is offering this program?

The program is offered through the National Institutes of Health (NIH), specifically the National Eye Institute (NEI).

What is the funding mechanism?

The funding mechanism is the NIH Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (T32). Under this structure, the award is made to an institution, and the institution is responsible for selecting trainees and managing their training experiences.

What training areas does the program emphasize?

The announcement emphasizes training in genomic medicine, computational genomics, statistical genetics, and genome informatics, specifically as these disciplines apply to vision and ophthalmic research.

Who is the training designed to support?

The training program is intended to support both predoctoral and postdoctoral trainees who are developing specialized skills in ophthalmic statistical genetics and bioinformatics.

What scientific workforce need is NEI addressing with this program?

NEI frames this as a growing need across basic, clinical, and translational ophthalmic research for investigators who can analyze large-scale genomic datasets, apply rigorous statistical methods, and use advanced computational approaches to generate meaningful biological and clinical insights about ocular disease.

What is the underlying scientific goal of the training program?

The underlying goal is to strengthen the workforce capable of identifying genes, genetic variants, and genomic mechanisms that contribute to ocular diseases.

How does the program support career development?

A major emphasis is career development for early-stage researchers. The program is designed to attract individuals early in their careers, expand their knowledge of the genetics of eye disorders, and encourage long-term research careers in statistical genetics, genome informatics, and related fields.

Who applies for the grant: individuals or institutions?

Institutions apply. The award is made to the institution, not directly to individual trainees. The institution then recruits, selects, and appoints trainees within the program it builds and maintains.

What types of organizations are eligible to apply?

Eligibility is oriented toward institutions capable of running an institutional training program. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, along with additional eligible categories referenced in the announcement (for example: Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs), among others described in the full announcement).

Does the program have expectations related to diversity in recruitment?

Yes. NEI notes that trainee recruitment and selection should include recruitment of individuals from diverse backgrounds, reflecting an expectation that programs broaden participation while developing technical and scientific expertise.

How many awards did NEI anticipate making?

NEI anticipated funding about four applications. However, the actual number of awards would depend on the availability of funds and the submission of a sufficient number of high-quality, competitive applications.

Do award size and duration follow a fixed standard?

The announcement indicates that award size and duration could vary because training programs differ in scope and design.

Is cost sharing or matching required?

No. The opportunity states that cost sharing or matching is not required.

What category and CFDA listing is associated with this opportunity?

It is listed as a discretionary grant in the health category, under CFDA 93.867 (Vision Research).

What are the key dates (posting, closing, archive)?

The posting date is January 27, 2010. The original closing date and the current closing date listed are May 18, 2012. The archive date is June 18, 2012.

Is this funding opportunity currently open?

Based on the listed closing date (May 18, 2012) and archive date (June 18, 2012), the announcement appears to be historical rather than currently open.

What is the overall long-term goal of NEI in offering this program?

Overall, the opportunity reflects NEI's longer-term commitment to expanding institutional capacity in statistical genetics and genome informatics for vision research by funding comprehensive, well-mentored training programs that produce researchers ready to address genetic and computational challenges in ocular disease discovery and translation.

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