Opportunity Information: Apply for RFA DK 16 007
Apply for RFA DK 16 007
- The HHS-NIH11 in the food and nutrition, health sector is offering a public funding opportunity titled "Neurocognitive Effects of Glycemic Dysregulation in Type 1 Diabetes (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847,.
- This funding opportunity was created on Jun 15, 2016 and posted on Jun 15, 2016.
- Applicants must submit their applications by Nov 14, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The funding opportunity titled "Neurocognitive Effects of Glycemic Dysregulation in Type 1 Diabetes (DP3)" (Funding Opportunity Number RFA DK 16 007) is a discretionary NIH grant program administered under HHS-NIH11. It focuses on advancing research into how glycemic dysregulation in type 1 diabetes relates to neurocognitive complications, meaning changes or impairments in brain function that can affect thinking, learning, memory, attention, processing speed, and other cognitive domains. The FOA is explicitly aimed at studies that deepen understanding of the neurological and cognitive consequences associated with type 1 diabetes, particularly as they may be driven by patterns of glucose instability such as hyperglycemia, hypoglycemia, and overall variability.
A defining feature of this announcement is its flexibility in study design and data sources. Applications may propose entirely new, stand-alone investigations, or they may leverage existing resources by using participants and/or biospecimens drawn from ongoing or completed clinical studies in type 1 diabetes. In practice, that means researchers can build a project around a fresh cohort designed specifically to answer neurocognitive questions, or they can efficiently add neurocognitive aims onto already-characterized clinical populations where detailed metabolic, clinical, and demographic data may already exist. This structure encourages both innovation and cost-effective use of valuable longitudinal cohorts and stored samples, which can be especially important when studying outcomes that may develop over time.
The activity category is listed under Food and Nutrition, Health, and the CFDA numbers associated with the opportunity are 93.847 (and the listing includes 93.847 as the primary identifier). The funding instrument is a grant, and the mechanism referenced in the title includes DP3, signaling a specific NIH funding mechanism intended for particular kinds of projects (often those that emphasize high-impact, potentially transformative research approaches). The stated award ceiling is up to $3,000,000, indicating that applicants can propose relatively substantial projects, potentially involving specialized neurocognitive testing, neuroimaging, advanced analytics, multicenter recruitment, or integration of clinical, biochemical, and cognitive endpoints. The announcement lists "ExpectedAwards:" without a number, so the precise number of awards anticipated is not specified in the provided data.
Eligibility is broad and includes a wide range of domestic organizations. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions where specified); for-profit organizations other than small businesses; small businesses; and Native American tribal governments and tribal organizations, as well as public housing authorities/Indian housing authorities. The presence of "Others (see text field entitled Additional Information on Eligibility for clarification)" suggests NIH also allowed additional categories or special cases as described in the full FOA text.
Key dates in the source information show the FOA was created and posted on June 15, 2016, with an original and current closing date of November 14, 2016. In other words, this was a time-limited call for applications during that period. The central purpose, as stated, is to invite applications that directly investigate neurocognitive complications linked to type 1 diabetes and glycemic dysregulation, either by launching new studies or by building on participants and samples from existing type 1 diabetes clinical research.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The funding opportunity is titled "Neurocognitive Effects of Glycemic Dysregulation in Type 1 Diabetes (DP3)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA DK 16 007.
Which agency administers this grant program?
This is a discretionary NIH grant program administered under HHS-NIH11.
What is the main goal of this opportunity?
The goal is to advance research on how glycemic dysregulation in type 1 diabetes relates to neurocognitive complications, including changes in brain function that can affect thinking, learning, memory, attention, processing speed, and other cognitive domains.
What does "neurocognitive complications" mean in the context of this FOA?
In this opportunity, neurocognitive complications refer to neurological and cognitive consequences that may occur in people with type 1 diabetes, such as impairments or changes in memory, attention, learning, processing speed, and related areas of cognition.
What aspects of glycemic dysregulation are emphasized?
The FOA highlights patterns of glucose instability, including hyperglycemia, hypoglycemia, and overall glycemic variability, as potential drivers of neurocognitive complications in type 1 diabetes.
What kinds of studies are allowed under this announcement?
The announcement is flexible and allows applications proposing entirely new, stand-alone investigations as well as studies that leverage existing resources from ongoing or completed type 1 diabetes clinical studies.
Can applicants use participants from existing type 1 diabetes studies?
Yes. Applications may use participants drawn from ongoing or completed clinical studies in type 1 diabetes.
Can applicants use biospecimens from existing studies?
Yes. Applications may use biospecimens from ongoing or completed clinical studies in type 1 diabetes.
Is the FOA designed to support adding neurocognitive aims onto existing cohorts?
Yes. The structure explicitly supports building on already-characterized clinical populations where metabolic, clinical, and demographic data may already exist, allowing applicants to add neurocognitive aims efficiently.
Why does the FOA emphasize the use of existing cohorts and samples?
Using longitudinal cohorts and stored samples can be a cost-effective way to study outcomes that may develop over time, which is often important when examining neurocognitive effects.
What is the activity category for this opportunity?
The activity category is listed under Food and Nutrition, Health.
What CFDA number(s) are associated with this opportunity?
The CFDA number listed is 93.847 (and it appears as the primary identifier in the provided information).
What is the funding instrument?
The funding instrument is a grant.
What does "DP3" indicate in the opportunity title?
The mechanism referenced includes DP3, which signals a specific NIH funding mechanism intended for particular kinds of projects, often those emphasizing high-impact, potentially transformative research approaches.
What is the maximum award amount (award ceiling)?
The award ceiling is up to $3,000,000.
Does the provided information specify how many awards NIH expects to make?
No. The listing shows "ExpectedAwards:" without a number, so the anticipated number of awards is not specified in the provided data.
Who is eligible to apply?
Eligibility is broad and includes many domestic organizations, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations with or without 501(c)(3) status (with exclusions where specified for higher education institutions)
- For-profit organizations other than small businesses
- Small businesses
- Native American tribal governments
- Native American tribal organizations
- Public housing authorities/Indian housing authorities
Are any additional applicant categories mentioned?
Yes. The eligibility section includes "Others (see text field entitled Additional Information on Eligibility for clarification)," indicating there may be additional categories or special cases described in the full FOA text.
When was the FOA posted?
The source information indicates the FOA was created and posted on June 15, 2016.
What was the application closing date?
The original and current closing date shown is November 14, 2016.
Is this a time-limited opportunity based on the provided dates?
Yes. Based on the provided dates, it was a time-limited call for applications during the period between June 15, 2016 and November 14, 2016.
What types of research activities could a project budget support (based on the ceiling and research focus described)?
With an award ceiling up to $3,000,000 and a neurocognitive focus, the provided description suggests projects could potentially involve specialized neurocognitive testing, neuroimaging, advanced analytics, multicenter recruitment, or integration of clinical, biochemical, and cognitive endpoints.
What is the central research focus applicants are expected to address?
The central purpose is to invite applications that directly investigate neurocognitive complications linked to type 1 diabetes and glycemic dysregulation, either through new studies or by using participants and samples from existing type 1 diabetes clinical research.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DK 16 007) also looked into and applied for these:
| Funding Opportunity |
|---|
| Metabolic Contributions to the Neurocognitive Complications of Diabetes: Ancillary Studies (R01) Apply for PAR 16 333 Funding Number: PAR 16 333 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Pediatric Centers of Excellence in Nephrology (P50) Apply for RFA DK 16 032 Funding Number: RFA DK 16 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| George M. O'Brien Kidney Research Core Centers (P30) Apply for RFA DK 16 031 Funding Number: RFA DK 16 031 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Promoting Organ and Tissue Donation Among Diverse Populations (R01) Apply for RFA DK 16 022 Funding Number: RFA DK 16 022 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $150,000 |
| Limited Competition for Data Coordinating Center (DCC) for NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U24) Apply for RFA DK 16 510 Funding Number: RFA DK 16 510 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,062,000 |
| NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genetic Research Centers (GRCs) (U01) Apply for RFA DK 16 029 Funding Number: RFA DK 16 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $293,000 |
| Coordinating Unit for the Mouse Metabolic Phenotyping Centers (U24) Apply for RFA DK 16 034 Funding Number: RFA DK 16 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,212,563 |
| Coordinating Unit for Diabetic Complications Consortium (U24) Apply for RFA DK 16 036 Funding Number: RFA DK 16 036 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $3,122,000 |
| APOL1 Long-term Kidney Transplantation Outcomes Network Scientific and Data Research Center (APOLLO SDRC) (Collaborative U01) Apply for RFA DK 16 024 Funding Number: RFA DK 16 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Limited Competition: Data Coordinating Center for Type 1 Diabetes TrialNet (UC4) Apply for RFA DK 16 505 Funding Number: RFA DK 16 505 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $45,000,000 |
| Limited Competition: Revision Application for the Human Islet Research Network Coordinating Center (U01) Apply for RFA DK 17 501 Funding Number: RFA DK 17 501 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $4,737,500 |
| Developmental Centers for Interdisciplinary Research in Benign Urology (P20) Apply for RFA DK 17 002 Funding Number: RFA DK 17 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $200,000 |
| George M. O'Brien Kidney Research Core Centers (P30) Apply for RFA DK 17 005 Funding Number: RFA DK 17 005 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Limited Competition: Follow-up on Subjects and Immunological Assessments in The Environmental Determinants of Diabetes In The Young Study (TEDDY) (UC4) Apply for RFA DK 17 508 Funding Number: RFA DK 17 508 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $27,000,000 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U24) Apply for RFA HL 17 028 Funding Number: RFA HL 17 028 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $3,245,000 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (UM2) Apply for RFA HL 17 031 Funding Number: RFA HL 17 031 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (UM1) Apply for RFA HL 17 026 Funding Number: RFA HL 17 026 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U54) Apply for RFA HL 17 025 Funding Number: RFA HL 17 025 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R01) Apply for RFA HL 17 029 Funding Number: RFA HL 17 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (P50) Apply for RFA HL 17 032 Funding Number: RFA HL 17 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
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