Opportunity Information: Apply for RFA HD 16 024

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Neurodevelopmental Assessment of Infants and Children in Resource Limited Settings (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Jul 7, 2015 and posted on Jul 7, 2015.
  • Applicants must submit their applications by Sep 14, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
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Opportunity Summary:

The grant opportunity titled "Neurodevelopmental Assessment of Infants and Children in Resource Limited Settings (R43/R44)" (Funding Opportunity Number RFA-HD-16-024) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) solicitation focused on creating practical, scalable ways to measure early cognitive and neurodevelopmental functioning in infants and children where resources are limited. The core aim is to support small businesses in developing new tools, technologies, and supporting materials that can be used to assess neurodevelopment in settings that may lack specialized clinicians, robust clinical infrastructure, stable power or internet, extensive training capacity, or access to standard assessment kits and proprietary testing materials. In other words, the FOA is about building assessment solutions that are realistic for low-resource environments while still producing meaningful, interpretable information about a child's development.

This is a discretionary grant opportunity using the SBIR phased mechanism R43/R44, meaning applicants can propose early-stage feasibility work (Phase I, R43) and, if successful, move toward further development and validation (Phase II, R44). The research emphasis is on tool and/or material development for neurodevelopmental assessment of cognitive functioning, with the intended end use being infants and children in resource-limited settings. Because the FOA is positioned within SBIR, it is geared toward innovations that can be developed into products or deployable solutions, not just academic studies. The expectation is that applicants will pursue research and development that could culminate in implementable assessment instruments, platforms, or support systems that can actually be used outside of well-resourced specialty centers.

The opportunity is administered by NIH and is associated with the broader federal activity area of Health, Income Security, and Social Services. It is linked to CFDA numbers 93.242 (Mental Health Research Grants) and 93.865 (Child Health and Human Development Extramural Research), reflecting the intersection of child development and mental health research priorities. The posted and creation date for the announcement was July 7, 2015, with an original and current closing date of September 14, 2015, and an archive date of October 15, 2015. While those dates indicate this specific FOA round is historic, the content still reflects NIH priorities that often reappear in later funding rounds under similar themes.

The estimated total funding amount listed for the FOA is $1,500,000, and there is no cost sharing or matching requirement, which generally lowers the barrier for small businesses that may not be able to provide substantial non-federal matching funds. Eligible applicants are small business concerns, consistent with SBIR rules. Foreign (non-U.S.) entities are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply. However, "foreign components" as defined by the NIH Grants Policy Statement may be allowed, which typically means a U.S.-based applicant may be able to include certain well-justified elements of work conducted abroad (for example, field testing, validation, or collaborations) when permitted under NIH policy and when it clearly strengthens the project and aligns with NIH requirements.

Practically speaking, the FOA is pointing innovators toward the real-world challenges of developmental assessment in low-resource contexts: tools may need to be low-cost, durable, portable, easy to administer, and interpretable by non-specialists with limited training. Solutions could involve simplified assessment protocols, culturally and linguistically adaptable materials, technology-assisted measures that reduce reliance on highly trained examiners, or systems that streamline scoring and interpretation. The emphasis on "tools and/or materials" also suggests that NIH is open to a broad range of deliverables, including but not limited to test instruments, administration guides, scoring systems, training packages, and implementation supports that make cognitive assessment feasible and reliable in the intended environments.

For applicants or interested parties seeking the official announcement text, the FOA provided an NIH link to the full solicitation at http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-16-024.html. For technical issues accessing the electronic announcement or linking problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this grant?

The opportunity is titled "Neurodevelopmental Assessment of Infants and Children in Resource Limited Settings (R43/R44)" and the Funding Opportunity Number is RFA-HD-16-024.

Which agency is offering this funding opportunity?

This solicitation is administered by the National Institutes of Health (NIH).

What type of grant mechanism does this opportunity use?

It uses the NIH Small Business Innovation Research (SBIR) phased mechanism R43/R44. This structure supports an initial feasibility stage (Phase I, R43) and, if successful, further development and validation (Phase II, R44).

What is the main purpose of this FOA?

The core purpose is to support small businesses in creating practical and scalable ways to measure early cognitive and neurodevelopmental functioning in infants and children in resource-limited settings.

Who is the intended population for the assessment tools developed under this FOA?

The intended end users are infants and children, with an emphasis on early developmental stages, in settings where resources are limited.

What kinds of settings does NIH mean by "resource limited" in this FOA?

The FOA highlights environments that may lack specialized clinicians, robust clinical infrastructure, stable power or internet, extensive training capacity, or access to standard assessment kits and proprietary testing materials.

What kind of work is NIH trying to support through this SBIR?

The research emphasis is on tool and/or material development for neurodevelopmental assessment of cognitive functioning. The focus is on building assessment solutions that can realistically be used outside well-resourced specialty centers while still producing meaningful and interpretable developmental information.

Is this opportunity geared more toward academic research or product-oriented development?

Because it is an SBIR solicitation, it is geared toward innovations that can be developed into products or deployable solutions, rather than purely academic studies.

What kinds of deliverables might be responsive to this FOA?

The FOA suggests a broad range of possible deliverables under "tools and/or materials," including test instruments, administration guides, scoring systems, training packages, and implementation supports that make cognitive assessment feasible and reliable in low-resource environments.

What practical design constraints does this FOA emphasize for assessment solutions?

The FOA points to real-world constraints in low-resource contexts. Solutions may need to be low-cost, durable, portable, easy to administer, and interpretable by non-specialists with limited training.

Does the FOA suggest any example approaches for making assessments workable in low-resource environments?

Yes. Examples mentioned include simplified assessment protocols, culturally and linguistically adaptable materials, technology-assisted measures that reduce reliance on highly trained examiners, and systems that streamline scoring and interpretation.

What is the estimated total funding amount listed for this FOA?

The estimated total funding amount listed is $1,500,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligible applicants are small business concerns, consistent with SBIR rules.

Are foreign (non-U.S.) entities eligible to apply?

No. Foreign (non-U.S.) entities are not eligible to apply.

Can a U.S. small business include non-U.S. components of its organization in the application?

No. The FOA states that non-U.S. components of U.S. organizations are also not eligible to apply.

Are any types of international involvement allowed at all?

The FOA indicates that "foreign components" (as defined by the NIH Grants Policy Statement) may be allowed. This typically means a U.S.-based applicant may be able to justify certain elements of work conducted abroad (such as field testing, validation, or collaborations) when permitted under NIH policy and when it strengthens the project and aligns with NIH requirements.

What federal activity area is this opportunity associated with?

The opportunity is associated with the broader federal activity area of Health, Income Security, and Social Services.

What CFDA numbers are linked to this opportunity?

The FOA is linked to CFDA 93.242 (Mental Health Research Grants) and CFDA 93.865 (Child Health and Human Development Extramural Research).

When was this FOA posted, and what were the key dates?

The posted/creation date was July 7, 2015. The original and current closing date was September 14, 2015. The archive date was October 15, 2015.

Is this a current funding opportunity?

The dates provided indicate that this specific FOA round is historic (it closed in 2015 and was archived in 2015). The description also notes that the content reflects NIH priorities that often reappear in later funding rounds under similar themes.

Where can applicants find the official announcement text?

The FOA provided a link to the full solicitation at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-16-024.html

Who should be contacted for technical issues accessing the electronic announcement?

For technical issues or linking problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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