Opportunity Information: Apply for RFA DA 15 009

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Neuroscience Information Framework (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
  • This funding opportunity was created on Jul 16, 2014 and posted on Jul 16, 2014.
  • Applicants must submit their applications by Sep 26, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $900,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments For profit organizations other than small businesses State governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Special district governments Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Neuroscience Information Framework (NIF) (U24) funding opportunity, RFA-DA-15-009, was a National Institutes of Health (NIH) cooperative agreement designed to support a single awardee in maintaining and advancing the Neuroscience Information Framework infrastructure and using it to identify "lacunas," meaning gaps in existing knowledge about the nervous system. In practical terms, the opportunity focused on strengthening a shared, community-facing informatics platform that helps researchers find, connect, and make sense of neuroscience data, tools, and resources, while also leveraging that infrastructure to reveal areas where data, standards, or research coverage are missing or insufficient.

This award used the U24 mechanism, which signals a cooperative agreement rather than a standard research grant. That typically means NIH expected to have substantial scientific and/or programmatic involvement during the project, such as active collaboration, coordination, or guidance around deliverables, priorities, and integration with broader NIH neuroscience data and informatics efforts. The overall emphasis was on infrastructure and utility for the field: building and sustaining capabilities that enable discovery and reuse, not just producing a standalone research finding.

The announcement was categorized as discretionary and spanned multiple activity areas (education, environment, health, income security and social services), reflecting the cross-cutting nature of neuroscience information resources and their relevance to many domains. The listed CFDA numbers covered a wide set of NIH programs, including drug abuse and addiction, mental health, alcohol research, neurological disorders, aging, vision, child health and development, nursing research, complementary and integrative health, and communication disorders, underscoring that NIF was intended to serve broad neuroscience and brain-health communities rather than a single disease area.

Funding details were straightforward: NIH expected to make one award with an estimated total funding amount of $900,000, and an award ceiling of $900,000. There was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds as a condition of the award. Key dates show this was a time-limited competition: it was posted July 16, 2014, with an original and current closing date of September 26, 2014, and it was archived October 27, 2014.

Eligibility was expansive across U.S.-based organizations. Eligible applicants included public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), small businesses and other for-profit organizations (other than small businesses were also included), independent school districts, and a wide range of government entities such as county, city/township, state, special district governments, and public housing authorities/Indian housing authorities. Tribal governments and tribal organizations were eligible, including federally recognized tribal governments, as well as other tribal entities. The FOA also explicitly listed a range of mission- or population-focused institutions and organizations as eligible, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs), along with faith-based and community-based organizations and U.S. territories or possessions.

At the same time, there were clear restrictions regarding foreign involvement. Non-U.S. entities (foreign organizations and foreign institutions) were not eligible to apply. Non-domestic components of U.S. organizations were also not eligible, and foreign components, as defined by the NIH Grants Policy Statement, were not allowed. In other words, applications had to be fully domestic in both applicant identity and project components.

For applicants or stakeholders seeking the full requirements, expectations, and any specific deliverables, the FOA directed readers to the official NIH grants page for RFA-DA-15-009. The contact information provided was primarily technical and administrative, pointing users who had trouble accessing the announcement or linking to it to the NIH Office of Extramural Research (OER) webmaster email.

Frequently Asked Questions (FAQs): Neuroscience Information Framework (NIF) (U24) - RFA-DA-15-009

What is the Neuroscience Information Framework (NIF) (U24) funding opportunity?

This opportunity (RFA-DA-15-009) was a National Institutes of Health (NIH) cooperative agreement that supported the maintenance and advancement of the Neuroscience Information Framework (NIF) infrastructure. It emphasized sustaining and improving a shared, community-facing informatics platform that helps neuroscience researchers find, connect, and interpret data, tools, and resources.

What was the main purpose of this award?

The main purpose was to strengthen and maintain NIF as an infrastructure resource for the broader neuroscience community, and to use that infrastructure to identify "lacunas" (gaps) in existing knowledge about the nervous system. The focus was on building and sustaining capabilities that enable discovery and reuse across the field, rather than producing a single standalone research result.

What does "lacunas" mean in the context of this opportunity?

In this context, "lacunas" refers to gaps in existing knowledge about the nervous system. Practically, the FOA described using NIF to reveal areas where data, standards, or research coverage are missing or insufficient.

What funding mechanism was used, and what does it imply?

The award used the U24 mechanism, which is a cooperative agreement rather than a standard research grant. This typically implies NIH anticipated substantial scientific and/or programmatic involvement during the project, such as active collaboration, coordination, or guidance around deliverables, priorities, and alignment with broader NIH neuroscience data and informatics efforts.

How many awards did NIH expect to make under this opportunity?

NIH expected to make one award.

What was the total estimated funding amount and award ceiling?

The estimated total funding amount was $900,000, and the award ceiling was also $900,000.

Was cost sharing or matching required?

No. The opportunity stated there was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds as a condition of the award.

When was the opportunity posted, and what were the key dates?

The opportunity was posted on July 16, 2014. The original and current closing date was September 26, 2014. It was archived on October 27, 2014.

Is this funding opportunity still open?

No. Based on the dates provided, the closing date was September 26, 2014, and the announcement was archived on October 27, 2014.

Who was eligible to apply?

Eligibility was broad across U.S.-based organizations. Eligible applicants included public and private institutions of higher education; nonprofits (with or without 501(c)(3) status); small businesses; other for-profit organizations (including those other than small businesses); independent school districts; and many types of government entities (county, city/township, state, special district governments, and public housing authorities/Indian housing authorities).

Were Tribal governments and Tribal organizations eligible?

Yes. The FOA listed federally recognized Tribal governments, as well as other Tribal entities and Tribal organizations, as eligible.

Were U.S. territories and possessions eligible?

Yes. The FOA explicitly included U.S. territories or possessions among eligible applicants.

Did the FOA explicitly include institution types such as HBCUs and Hispanic-serving institutions?

Yes. The eligibility list explicitly included Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs). It also listed faith-based and community-based organizations as eligible.

Were foreign organizations eligible to apply?

No. Non-U.S. entities (foreign organizations and foreign institutions) were not eligible to apply.

Could a U.S. organization include a non-U.S. (non-domestic) component in the project?

No. Non-domestic components of U.S. organizations were not eligible, and foreign components (as defined by the NIH Grants Policy Statement) were not allowed. Applications had to be fully domestic in both applicant identity and project components.

What kinds of activity areas did the announcement span?

The announcement was categorized as discretionary and spanned multiple activity areas: education, environment, health, income security, and social services. This reflected the cross-cutting role of neuroscience information resources and their relevance across domains.

Did the opportunity target only one disease area or institute mission?

No. The listed CFDA numbers covered a wide range of NIH programs (including areas such as drug abuse and addiction, mental health, alcohol research, neurological disorders, aging, vision, child health and development, nursing research, complementary and integrative health, and communication disorders). This indicated the NIF resource was intended to serve broad neuroscience and brain-health communities rather than a single disease area.

What was the practical focus of the infrastructure work described?

The FOA emphasized strengthening a shared informatics platform that helps researchers find, connect, and make sense of neuroscience data, tools, and resources. It also emphasized using the platform to identify gaps where data, standards, or research coverage are missing or insufficient.

Where were applicants directed to find the full official requirements and expectations?

The FOA directed readers to the official NIH grants page for RFA-DA-15-009 for the full requirements, expectations, and any specific deliverables.

Who was listed as a contact for technical issues accessing the announcement?

The contact information provided was primarily technical and administrative, directing users who had trouble accessing the announcement or linking to it to the NIH Office of Extramural Research (OER) webmaster email.

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