Opportunity Information: Apply for PAS 13 006
Apply for PAS 13 006
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "New Directions in Hematology Research (SHINE II) (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Apr 1, 2015 and posted on Oct 10, 2012.
- Applicants must submit their applications by Apr 1, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Special district governments County governments State governments Private institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Small businesses Native American tribal governments (Federally recognized) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply.Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
New Directions in Hematology Research (SHINE II) (R01) is an NIH funding opportunity (PAS-13-006) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to spark fresh, high-impact directions in hematology research. The program is designed for investigators who want to test bold, potentially field-shifting ideas that could open up new lines of discovery relevant to NIDDKs hematology mission. SHINE II specifically builds on the earlier SHINE initiative (PAS-10-046, Stimulating Hematology Investigation New Endeavors) by continuing to encourage creative, exploratory hematology projects, but with an emphasis on focused validation of novel concepts rather than broad, multi-aim research plans.
The core intent is to support preclinical, proof-of-principle work that can demonstrate whether an innovative concept or approach is actually viable. In practice, this means projects should be tightly scoped, aimed at answering one central question or validating one key concept that could serve as a foundation for larger studies later. Compared with a typical R01, the applications are expected to be narrower and faster-moving, with a shorter project period of about 1 to 3 years and a structure centered on a single main aim, rather than multiple extensive aims.
From a funding and administrative standpoint, this is a discretionary grant opportunity under the NIH umbrella, categorized in the health area (CFDA 93.847, Diabetes, Digestive, and Kidney Diseases Extramural Research). The announcement listed an estimated total program funding level of about $1,000,000 and an award ceiling of $200,000, with no cost-sharing or matching requirement. In other words, applicants are not expected to provide matching funds as a condition of receiving an award.
Eligibility is broad across many types of domestic organizations. Eligible applicants include a wide range of nonprofit and governmental entities, public and private institutions of higher education, independent school districts, for-profit organizations (other than small businesses), and small businesses. The eligibility language also explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, among others. At the same time, foreign institutions are not eligible to apply directly, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined in the NIH Grants Policy Statement are allowed, which can matter for projects that require specific expertise, cohorts, samples, or collaboration outside the United States.
Timing details in the source record indicate it was posted on October 10, 2012, with administrative dates showing creation on April 1, 2015 and an original closing date of May 7, 2015, alongside a current closing date of April 1, 2015 and an archive date of May 1, 2015. The full announcement and requirements were provided through the NIH Grants Guide link: http://grants.nih.gov/grants/guide/pa-files/PAS-13-006.html. For access or technical issues with the online posting, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, SHINE II is best understood as a targeted R01-style mechanism meant to quickly test and validate novel hematology ideas with strong potential payoff. The program pushes applicants to keep the project compact and decisive, generating the kind of early evidence that can justify and guide larger, more comprehensive follow-on research.
FAQs: New Directions in Hematology Research (SHINE II) (R01) - PAS-13-006
What is the SHINE II funding opportunity?
New Directions in Hematology Research (SHINE II) (R01) is an NIH funding opportunity (PAS-13-006) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to encourage fresh, high-impact directions in hematology research.
What is the main goal of SHINE II?
The main goal is to spark bold, potentially field-shifting hematology ideas and support early work that can validate whether a new concept or approach is viable, especially when it could open up new discovery paths aligned with NIDDK's hematology mission.
How is SHINE II different from a typical NIH R01?
Compared with a typical R01, SHINE II expects a narrower, faster-moving project. Applications are intended to be tightly scoped and centered on a single main aim rather than multiple broad aims, with a shorter project period (about 1 to 3 years).
What kind of research does SHINE II prioritize?
SHINE II prioritizes preclinical, proof-of-principle work designed to validate one key concept or answer one central question. The emphasis is on focused validation of novel concepts rather than broad, multi-aim research plans.
Is SHINE II meant for exploratory ideas or fully developed programs?
It is designed for creative, exploratory hematology projects, but with an emphasis on validating a novel concept in a focused way. The intent is to generate early evidence that could support larger follow-on studies later.
Does SHINE II build on an earlier NIH initiative?
Yes. SHINE II builds on the earlier SHINE initiative, Stimulating Hematology Investigation New Endeavors (PAS-10-046), continuing to encourage innovative hematology projects while putting more weight on focused validation.
What is the funding agency and institute for this opportunity?
The opportunity is under the NIH umbrella and is issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What is the CFDA number and program category associated with this opportunity?
The opportunity is categorized in the health area under CFDA 93.847, Diabetes, Digestive, and Kidney Diseases Extramural Research.
What is the estimated total program funding level?
The announcement listed an estimated total program funding level of about $1,000,000.
What is the award ceiling for a single SHINE II award?
The award ceiling listed is $200,000.
Is cost-sharing or matching required?
No. The announcement states there is no cost-sharing or matching requirement. Applicants are not expected to provide matching funds as a condition of receiving an award.
What is the expected project period?
The expected project period is about 1 to 3 years, reflecting the program's intent to move quickly and decisively on proof-of-principle validation.
How should the project be structured?
Projects are expected to be tightly scoped and structured around a single main aim focused on validating one novel concept, rather than a broad plan with multiple extensive aims.
Who is this opportunity intended for?
It is intended for investigators who want to test bold, potentially field-shifting ideas in hematology that align with NIDDK's mission, especially those aiming to validate an innovative concept as a foundation for later, larger studies.
What types of U.S. organizations are eligible to apply?
Eligibility is broad across many types of domestic organizations, including nonprofit and governmental entities, public and private institutions of higher education, independent school districts, for-profit organizations (other than small businesses), and small businesses.
Are minority-serving and community-based organizations included in the eligibility language?
Yes. The eligibility language explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, among others.
Can a foreign institution apply directly as the applicant organization?
No. Foreign institutions are not eligible to apply directly.
Can a non-U.S. component of a U.S. organization apply?
No. Non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed in SHINE II projects?
Yes. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. This may be relevant when a project requires specific expertise, cohorts, samples, or collaboration outside the United States.
What is the official NIH funding opportunity number and title?
The official opportunity is PAS-13-006, titled New Directions in Hematology Research (SHINE II) (R01).
Where can applicants find the full announcement details?
The full announcement and requirements are available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAS-13-006.html
What dates are associated with this opportunity in the source record?
The source record indicates the opportunity was posted on October 10, 2012. It also shows administrative dates including creation on April 1, 2015, an original closing date of May 7, 2015, a current closing date of April 1, 2015, and an archive date of May 1, 2015.
Who should be contacted for access or technical issues with the online posting?
For access or technical issues with the online posting, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
How should SHINE II be understood in practical terms?
SHINE II is best understood as a targeted R01-style mechanism intended to quickly test and validate novel hematology ideas with strong potential payoff, producing early evidence that can justify and guide more comprehensive follow-on research.
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