Opportunity Information: Apply for PA 15 076

  • The National Institutes of Health in the food and nutrition health income security and social services sector is offering a public funding opportunity titled "New Technologies for Viral Hepatitis STTR (R41/R42)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Dec 18, 2014 and posted on Dec 18, 2014.
  • Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity. A small business concern is one that, at the time of award of Phase I and Phase II, meets all of the following criteria 1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor 2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture 3. i. SBIR and STTR. Be a concern which is more than 50 directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50 directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these OR ii. SBIR only. Be a concern which is more than 50 owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50 of the concern OR iii. SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with 121.705(b) concerning registration and proposal requirements. 4. Has, including its affiliates, not more than 500 employees.
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Opportunity Summary:

The New Technologies for Viral Hepatitis STTR (R41/R42) funding opportunity (PA-15-076) is a National Institutes of Health (NIH) grant program designed to push forward practical, innovative technologies that can improve how viral hepatitis is prevented, detected, monitored, and treated. The central intent is to bring small business innovation directly into viral hepatitis research and product development, aligning proposed work with priorities described in the U.S. Department of Health and Human Services Action Plan for the Prevention, Care and Treatment of Viral Hepatitis, while also fitting within the research missions of the NIH institutes participating in the announcement. In other words, it is structured to help move new ideas from early proof-of-concept into more mature development steps that could ultimately support real-world tools, platforms, or interventions related to hepatitis.

This opportunity uses the STTR mechanism, meaning it is specifically built around a formal research partnership between a U.S. small business and a nonprofit research institution (such as a university, medical center, or research institute). The funding mechanism is the NIH STTR phased award pathway: Phase I (R41) typically supports early feasibility and proof-of-concept work, while Phase II (R42) supports further research and development to advance the technology toward commercialization or broader implementation. The listing indicates it is a discretionary grant program with no cost sharing or matching requirement, which is important for small companies because it reduces the need for outside committed funds as a condition of applying.

Eligibility is limited to U.S. small business concerns (SBCs). To qualify, the applicant organization must be for-profit, have a place of business in the United States, and primarily operate in the U.S. (or otherwise make a significant contribution to the U.S. economy through taxes or the use of American labor, products, or materials). The business must be an allowable legal entity type (for example, an LLC or corporation), and it must employ no more than 500 employees including affiliates. The ownership and control requirements follow federal SBIR/STTR rules, allowing eligibility for companies that are majority owned and controlled by U.S. citizens or permanent residents, as well as certain venture-backed structures under specific conditions. Joint ventures can apply as well, provided they meet the detailed ownership and participation requirements described in the announcement.

From an administrative standpoint, this FOA was posted on December 18, 2014, and it carried an application window that closed on January 7, 2018, with an archive date of February 7, 2018. It is associated with multiple CFDA program areas, reflecting the cross-cutting nature of viral hepatitis work across NIH, including blood diseases and resources research (93.839), diabetes/digestive/kidney diseases extramural research (93.847), and child health and human development extramural research (93.865). That mix signals that applications could span a range of hepatitis-related needs, from diagnostics and screening tools to care delivery technologies and potentially pediatric or maternal-child dimensions, depending on the specific institute mission fit.

Overall, PA-15-076 is best read as an NIH effort to translate hepatitis-focused innovation into tangible technologies by leveraging the commercialization-driven structure of STTR. The program is aimed at small businesses ready to collaborate with research institutions to develop new approaches that support national viral hepatitis prevention and treatment goals. For the full announcement details (including specific scientific interests, application instructions, review criteria, and participating institutes), the source link is: http://grants.nih.gov/grants/guide/pa-files/PA-15-076.html, and technical access issues were handled through the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

FAQs: New Technologies for Viral Hepatitis STTR (R41/R42) - PA-15-076

What is PA-15-076?

PA-15-076 is the NIH funding opportunity announcement titled "New Technologies for Viral Hepatitis STTR (R41/R42)." It is a grant program designed to advance practical, innovative technologies that improve how viral hepatitis is prevented, detected, monitored, and treated.

What is the main goal of this funding opportunity?

The central goal is to move new hepatitis-focused technology ideas from early proof-of-concept toward more mature development steps that could support real-world tools, platforms, or interventions. It emphasizes translation and product development aligned with national viral hepatitis priorities and the missions of participating NIH institutes.

What types of projects does this program aim to support?

Projects are expected to focus on innovative technologies for viral hepatitis prevention, detection, monitoring, or treatment. The description suggests a broad range of possible technology directions, including diagnostics and screening tools, care delivery technologies, and other practical approaches that could be developed toward implementation.

How does this opportunity align with U.S. government priorities?

Proposed work is intended to align with priorities described in the U.S. Department of Health and Human Services Action Plan for the Prevention, Care and Treatment of Viral Hepatitis, while also fitting within the research missions of the NIH institutes participating in the announcement.

What funding mechanism is used for PA-15-076?

This opportunity uses the NIH STTR mechanism and specifically the STTR phased award pathway: Phase I is R41 and Phase II is R42.

What is the difference between Phase I (R41) and Phase II (R42) in this program?

Phase I (R41) typically supports early feasibility and proof-of-concept work. Phase II (R42) supports further research and development to advance the technology toward commercialization or broader implementation.

Is this program focused on commercialization?

Yes. The opportunity is structured to leverage the commercialization-driven nature of STTR so that small business-led innovation can translate into tangible hepatitis-related technologies and products.

Who is eligible to apply?

Eligibility is limited to U.S. small business concerns (SBCs) that meet federal STTR requirements.

What are the basic small business requirements to be eligible?

The applicant organization must be for-profit, have a place of business in the United States, and primarily operate in the U.S. or otherwise make a significant contribution to the U.S. economy through taxes or the use of American labor, products, or materials.

Are there size limits for the applicant small business?

Yes. The business must employ no more than 500 employees, including affiliates.

What legal entity types can apply?

The business must be an allowable legal entity type, such as an LLC or a corporation, as referenced in the announcement.

Do applicants need a research partner?

Yes. Because this is an STTR opportunity, it is built around a formal research partnership between a U.S. small business and a nonprofit research institution, such as a university, medical center, or research institute.

What kinds of organizations can serve as the nonprofit research institution partner?

The nonprofit research institution partner can be a university, medical center, or research institute, as examples provided in the opportunity description.

Are there ownership and control requirements for the small business?

Yes. Ownership and control follow federal SBIR/STTR rules. Eligibility includes companies that are majority owned and controlled by U.S. citizens or permanent residents, as well as certain venture-backed structures under specific conditions described in the announcement.

Can joint ventures apply?

Yes. Joint ventures can apply if they meet the detailed ownership and participation requirements described in the announcement.

Is cost sharing or matching required?

No. The listing indicates this is a discretionary grant program with no cost sharing or matching requirement.

When was this funding opportunity posted?

The FOA was posted on December 18, 2014.

When did the application window close?

The application window closed on January 7, 2018.

When was the opportunity archived?

The archive date was February 7, 2018.

Which agencies and institutes are involved?

The program is run through the National Institutes of Health (NIH) and involves multiple participating NIH institutes, with projects expected to fit within those institutes' research missions.

What CFDA program areas are associated with this opportunity?

The opportunity is associated with multiple CFDA program areas, including 93.839 (blood diseases and resources research), 93.847 (diabetes/digestive/kidney diseases extramural research), and 93.865 (child health and human development extramural research).

What does it mean that multiple CFDA areas are listed?

It signals that viral hepatitis work in this announcement is cross-cutting across NIH and could span different hepatitis-related needs, depending on the institute mission fit, including diagnostics, screening, care delivery technologies, and potentially pediatric or maternal-child dimensions.

Where can applicants find the full official announcement?

The full announcement (including specific scientific interests, application instructions, review criteria, and participating institutes) is available at: http://grants.nih.gov/grants/guide/pa-files/PA-15-076.html.

Who should be contacted for technical access issues related to the announcement?

Technical access issues were handled through the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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