Opportunity Information: Apply for RFA HG 15 026
Apply for RFA HG 15 026
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHGRI Genome Sequencing Program Analysis Centers (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
- This funding opportunity was created on Jun 3, 2015 and posted on Jun 3, 2015.
- Applicants must submit their applications by Aug 25, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses Independent school districts State governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Special district governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NHGRI Genome Sequencing Program Analysis Centers (GSPAC) opportunity (Funding Opportunity Number RFA-HG-15-026) is a National Institutes of Health (NIH) funding announcement from the National Human Genome Research Institute (NHGRI) to create a small number of dedicated analysis centers focused on making sense of large-scale genome sequencing data. The core purpose is not to generate new sequencing data, but to carry out computational and statistical analyses on data produced by the NHGRI Genome Sequencing Program (GSP) and turn those datasets into genomic and biological insights. In practical terms, the centers funded under this announcement are meant to function as hubs of expertise for large, complex genomics analyses, developing and applying methods, integrating results, and helping ensure that the sequencing program produces interpretable, useful knowledge rather than just raw data.
This program uses a cooperative agreement mechanism (U01), which typically means NIH expects substantial scientific coordination and interaction between awardees and NHGRI program staff. Compared with a standard research grant, a U01 often comes with more structured collaboration, shared goals, and active program-level management. The announcement sits in the health funding category and is categorized as discretionary funding.
NHGRI anticipated making about four awards under this announcement, with an estimated total funding level of $3,000,000. The posting date and creation date were June 3, 2015, with an original (and current) application due date of August 25, 2015, and an archive date of September 25, 2015. Cost sharing or matching funds were not required. The CFDA program number associated with the opportunity is 93.172 (Human Genome Research).
Eligibility was broad across many organization types, reflecting NHGRI interest in attracting strong computational genomics and data science teams from a wide range of settings. Eligible applicants included public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), for-profit organizations other than small businesses, and small businesses, as well as various levels of government entities (state, county, city or township, special district governments, and independent school districts). The announcement also explicitly included a variety of mission- and community-focused institutions and organizations in its eligibility list, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. Tribal organizations were included as eligible (both federally recognized tribal governments and other tribal entities), and public housing authorities/Indian housing authorities were also listed.
On the international side, the notice drew a clear boundary: non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions were not eligible to apply as applicant organizations. However, non-domestic components of U.S. organizations were allowed to apply, and foreign components (as defined in the NIH Grants Policy Statement) were permitted, meaning a U.S.-based applicant could include certain foreign elements in the work if allowed under NIH policy and justified by the project needs.
Operationally, the centers envisioned by this funding opportunity were expected to perform computational analyses on GSP-produced datasets with the aim of extracting knowledge, which generally implies activities like developing or applying scalable analytic pipelines, statistical and machine learning methods, integrative analyses across datasets, and interpretation frameworks that connect genomic variation to biological function or disease relevance. The emphasis on “extracting genomic and biological knowledge” signals that deliverables were expected to go beyond routine processing and include higher-level discovery, synthesis, and interpretation that increase the value of the underlying sequencing investments. The announcement also references companion funding opportunities for the broader Genome Sequencing Program, suggesting these analysis centers were intended to plug into a larger coordinated ecosystem where different awards produce data and others analyze it, with cross-project alignment.
For reference and full details, the announcement’s additional information link was provided through the NIH grants guide (RFA-HG-15-026). For technical issues accessing or linking to the announcement, the listed contact was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NHGRI Genome Sequencing Program Analysis Centers (GSPAC) - RFA-HG-15-026
What is the NHGRI Genome Sequencing Program Analysis Centers (GSPAC) opportunity?
It is an NIH funding opportunity from the National Human Genome Research Institute (NHGRI) to create a small number of dedicated analysis centers focused on making sense of large-scale genome sequencing data generated by the NHGRI Genome Sequencing Program (GSP).
What is the main purpose of these analysis centers?
The core purpose is to conduct computational and statistical analyses on GSP-produced datasets and turn those datasets into genomic and biological insights, ensuring the sequencing program yields interpretable, useful knowledge rather than only raw data.
Is this opportunity intended to generate new genome sequencing data?
No. The core purpose is not to generate new sequencing data. The emphasis is on analyzing existing large-scale sequencing datasets produced by the NHGRI Genome Sequencing Program (GSP).
What kinds of activities are the funded centers expected to perform?
The centers are expected to perform computational analyses intended to extract knowledge from GSP datasets. This generally implies work such as developing or applying scalable analytic pipelines, computational/statistical methods, integrative analyses across datasets, and interpretation frameworks that connect genomic variation to biological function or disease relevance.
What does NHGRI mean by "extracting genomic and biological knowledge"?
The language signals that deliverables should go beyond routine data processing. The expectation is higher-level discovery, synthesis, and interpretation that increases the value of the underlying sequencing investments.
How will these centers fit into the broader NHGRI Genome Sequencing Program?
The announcement references companion funding opportunities for the broader Genome Sequencing Program, indicating these analysis centers are meant to plug into a larger coordinated ecosystem where some awards produce data and others focus on analysis, with cross-project alignment.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is RFA-HG-15-026.
What NIH Institute is sponsoring this opportunity?
The sponsoring institute is the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH).
What funding mechanism is used for this opportunity?
This opportunity uses a cooperative agreement mechanism (U01).
What does a U01 cooperative agreement imply about how the award will be managed?
A U01 typically means NIH expects substantial scientific coordination and interaction between awardees and NHGRI program staff. Compared with a standard research grant, it often includes more structured collaboration, shared goals, and active program-level management.
How many awards did NHGRI anticipate making under this announcement?
NHGRI anticipated making about four awards.
What was the estimated total funding level for the opportunity?
The estimated total funding level was $3,000,000.
Is cost sharing or matching required?
No. Cost sharing or matching funds were not required.
What is the CFDA program number associated with this opportunity?
The CFDA program number is 93.172 (Human Genome Research).
What is the application due date?
The application due date listed was August 25, 2015.
When was the opportunity posted and created?
The posting date and creation date were both June 3, 2015.
When was the opportunity archived?
The archive date was September 25, 2015.
What is the funding category and type?
The announcement sits in the health funding category and is categorized as discretionary funding.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofits (including 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; small businesses; and various government entities (state, county, city or township, special district governments, and independent school districts).
Are minority-serving institutions explicitly included as eligible applicants?
Yes. The eligibility list explicitly included Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible to apply?
Yes. Faith-based or community-based organizations were explicitly included in the eligibility list.
Are tribal organizations eligible to apply?
Yes. Tribal organizations were included as eligible, including federally recognized tribal governments and other tribal entities.
Are public housing authorities or Indian housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities were listed as eligible applicants.
Are federal agencies eligible to apply?
Yes. The eligibility list included eligible federal agencies.
Can non-U.S. (non-domestic) organizations apply as the applicant organization?
No. Non-domestic (non-U.S.) entities and non-domestic institutions were not eligible to apply as applicant organizations.
Can a U.S.-based applicant include foreign components in the project?
Yes. Non-domestic components of U.S. organizations were allowed to apply, and foreign components (as defined in the NIH Grants Policy Statement) were permitted, meaning a U.S.-based applicant could include certain foreign elements if allowed under NIH policy and justified by project needs.
Where can applicants find the full announcement details?
The additional information link was provided through the NIH grants guide for RFA-HG-15-026.
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues accessing or linking to the announcement, the listed contact was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
In practical terms, what role are the analysis centers supposed to play?
They are meant to function as hubs of expertise for large, complex genomics analyses by developing and applying methods, integrating results, and helping ensure the sequencing program produces interpretable and useful knowledge.
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