Opportunity Information: Apply for RFA HL 16 025
Apply for RFA HL 16 025
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "NHLBI Early Investigator Award (EIA) (R35)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839,.
- This funding opportunity was created on Dec 10, 2015 and posted on Dec 10, 2015.
- Applicants must submit their applications by Apr 15, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The NHLBI Early (or Emerging) Investigator Award (EIA) (R35), listed under Funding Opportunity Number RFA-HL-16-025, is a discretionary NIH grant program run through the Department of Health and Human Services, National Institutes of Health (specifically the National Heart, Lung, and Blood Institute, NHLBI). Its main goal is to boost research productivity and spark innovation in heart, lung, blood, and sleep (HLBS) science by giving promising investigators longer-term, more flexible support than typical project-by-project funding. The idea is to let strong early-career researchers spend less time constantly writing new grant applications and more time actually doing ambitious, creative research that can meaningfully move their fields forward.
This opportunity is specifically designed for Program Directors/Principal Investigators (PDs/PIs) who already have a demonstrated NHLBI funding track record. To be eligible in the way the program describes, the investigator must currently hold two NHLBI R01 awards, and one of those must be an NHLBI-funded NIH Early Stage Investigator (ESI) R01. In other words, it is not aimed at brand-new investigators who have not yet secured major NIH funding; it targets investigators who have already broken through with R01-level support early in their careers and have shown the momentum, independence, and quality of research to justify a more sustained investment. Beyond the basic award history, the program emphasizes that applicants should have an outstanding research record that indicates they are likely to make major contributions to HLBS research over time.
Administratively, the award uses the NIH R35 activity code, which generally signals a “research program” style award rather than a narrowly defined single project. The practical implication is flexibility: instead of being locked into a tightly scoped set of aims that must be followed exactly as originally proposed, the investigator is supported in a way that can better accommodate scientific pivots, new directions, and emerging opportunities, as long as the work remains aligned with NHLBI priorities in heart, lung, blood, and sleep research. This structure is meant to encourage bolder, potentially higher-impact work and reduce the inefficiencies that can come from repeatedly packaging research into separate R01 applications.
The posted financial information indicates an award ceiling of $600,000 (as listed in the source data). The funding instrument type is a grant, and the funding activity category is health. The opportunity is associated with CFDA numbers 93.233, 93.837, 93.838, and 93.839, which correspond to NHLBI-related assistance listings and reflect the institute’s broad mission areas that cover HLBS conditions and related biomedical research.
Eligibility, as provided in the listing, is broad at the institutional level and includes many common applicant organization types: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3) categories, excluding higher education where specified); for-profit organizations (other than small businesses); and small businesses. The listing also notes “Others” with a prompt to consult the additional eligibility text for clarification, indicating that there may be further nuance in the full announcement. Even with broad organizational eligibility, the key gating factor for this particular award is really the investigator’s status and funding history (two NHLBI R01s, including one ESI R01), which is what makes this a targeted mechanism for a relatively small pool of established early investigators.
In terms of timing and status, the opportunity was created and posted on December 10, 2015, with an original and current closing date of April 15, 2018. That means the specific solicitation referenced here was tied to that submission deadline, and anyone looking to pursue an EIA-style award today would typically need to check whether NHLBI has reissued the program under an updated funding opportunity announcement number, revised dates, or modified requirements.
Overall, the EIA (R35) can be understood as NHLBI’s way of “doubling down” on researchers who have already demonstrated early success and strong potential. By offering longer-term, more adaptable support, the institute aims to accelerate impactful discovery and maintain a strong pipeline of innovative investigators working on major problems in heart, lung, blood, and sleep health.
Frequently Asked Questions (FAQs): NHLBI Early (or Emerging) Investigator Award (EIA) (R35) - RFA-HL-16-025
What is the NHLBI Early (or Emerging) Investigator Award (EIA) (R35)?
The NHLBI Early (or Emerging) Investigator Award (EIA) is a discretionary NIH grant program from the National Heart, Lung, and Blood Institute (NHLBI). It uses the NIH R35 activity code and is intended to provide longer-term, more flexible support to promising investigators working in heart, lung, blood, and sleep (HLBS) research.
What is the goal of this award?
The main goal is to boost research productivity and spark innovation in HLBS science by supporting an investigator's overall research program (rather than funding one narrowly defined project at a time). The program is designed to reduce time spent repeatedly writing new grant applications and increase time spent doing ambitious, creative research.
Which agency and institute run this opportunity?
This opportunity is run through the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), specifically the National Heart, Lung, and Blood Institute (NHLBI).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-HL-16-025.
What does it mean that this is an R35 award?
The NIH R35 activity code generally indicates a "research program" style award. In practical terms, it emphasizes flexibility and longer-term support, so the investigator can adapt, pivot, and pursue emerging scientific opportunities while staying aligned with NHLBI priorities in heart, lung, blood, and sleep research.
Is this funding meant for a single project or a broader research program?
This mechanism is described as supporting a broader research program rather than a narrowly defined single project. The intent is to avoid locking investigators into a tightly scoped set of aims and instead enable scientific pivots and new directions over time (while remaining within NHLBI's HLBS mission areas).
Who is this award designed for?
It is specifically designed for Program Directors/Principal Investigators (PDs/PIs) who already have a demonstrated NHLBI funding track record and an outstanding research record suggesting they are likely to make major long-term contributions to HLBS research.
Is this award meant for brand-new investigators?
No. Based on the eligibility description provided, it is not aimed at investigators who have not yet secured major NIH funding. It targets early-career investigators who have already obtained R01-level support and demonstrated momentum and independence.
What specific investigator funding history is required to be eligible?
To be eligible as described, the investigator must currently hold two NHLBI R01 awards, and one of those must be an NHLBI-funded NIH Early Stage Investigator (ESI) R01.
What is the significance of needing an ESI R01?
The listing frames the ESI R01 requirement as evidence that the investigator secured R01-level support early in their career and has already demonstrated strong potential and independence within NHLBI-funded research.
What research areas does NHLBI consider in-scope for this award?
The award is intended to support science aligned with NHLBI priorities in heart, lung, blood, and sleep (HLBS) research.
How does this award encourage innovation?
It is structured to provide longer-term and more adaptable support than typical project-by-project funding, which is meant to encourage bolder, potentially higher-impact research and allow investigators to pursue new directions as science evolves.
What is the funding instrument type?
The funding instrument type is a grant.
What is the funding activity category?
The funding activity category is health.
What is the award ceiling listed for this opportunity?
The posted financial information indicates an award ceiling of $600,000 (as listed in the source data).
Which CFDA numbers are associated with this opportunity?
The opportunity is associated with CFDA numbers 93.233, 93.837, 93.838, and 93.839, reflecting NHLBI-related assistance listings tied to the institute's mission areas in HLBS conditions and biomedical research.
What types of organizations are eligible to apply?
Institutional eligibility is described as broad and includes: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (501(c)(3) and non-501(c)(3), excluding higher education where specified); for-profit organizations (other than small businesses); and small businesses.
If many organization types are eligible, what is the main limiting factor?
Even with broad organizational eligibility, the key gating factor highlighted is the investigator's eligibility and funding history (specifically, holding two NHLBI R01 awards, including one NHLBI-funded ESI R01).
The eligibility section mentions "Others." What does that mean?
The listing notes "Others" and instructs applicants to consult the additional eligibility text for clarification, suggesting there may be additional nuances in the full funding opportunity announcement.
When was this opportunity posted?
The opportunity was created and posted on December 10, 2015.
What was the closing date for this specific solicitation?
The original and current closing date listed is April 15, 2018.
Is this opportunity still open based on the dates provided?
Based on the provided closing date of April 15, 2018, this specific solicitation is tied to that deadline and would be considered closed.
If someone wants an EIA-style award now, what should they do?
The description indicates that anyone interested today would typically need to check whether NHLBI has reissued the program under an updated funding opportunity announcement number, revised dates, or modified requirements.
In plain terms, what is NHLBI trying to do with this program?
The program can be understood as NHLBI "doubling down" on investigators who have already demonstrated early success and strong potential. The purpose is to accelerate impactful discovery by providing longer-term, more flexible support for innovative HLBS research.
Browse more opportunities from the same category: Health
Next opportunity: TECHNICAL ASSISTANCE TO BROWNFIELDS COMMUNITIES
Previous opportunity: Comprehensive Community-Based HIV Prevention, Linkage, and Retention Services for Key Populations and Adolescent Girls and Young Women in the United Republic of Tanzania under the President’s Emergency Plan for AIDS Relief (PEPFAR)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA HL 16 025
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA HL 16 025) also looked into and applied for these:
| Funding Opportunity |
|---|
| Supporting Implementation of HIV and TB Services for Epidemic Control in the Republic of Mozambique under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1632 Funding Number: CDC RFA GH16 1632 Agency: HHS-CDC-CGH Category: Health Funding Amount: $80,000,000 |
| Enhancing the Government of India’s Capacity to Scale Up and Improve Comprehensive HIV Service Package Quality for People Who Inject Drugs under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 154202CONT16 Funding Number: CDC RFA GH15 154202CONT16 Agency: HHS-CDC Category: Health Funding Amount: Case Dependent |
| Flex Rural Veterans Health Access Program Apply for HRSA 16 015 Funding Number: HRSA 16 015 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| Targeted Capacity Expansion-Peer-to-Peer (Short Title: TCE-PTP) Apply for TI 16 008 Funding Number: TI 16 008 Agency: HHS-SAMHS Category: Health Funding Amount: $250,000 |
| Implementing Comprehensive Community Based HIV/AIDS Prevention, Care and Treatment Services in Priority Areas in the Republic of Zambia under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1668 Funding Number: CDC RFA GH16 1668 Agency: HHS-CDC-CGH Category: Health Funding Amount: $2,500,000 |
| Cooperative Agreements for Adolescent and Transitional Aged Youth Treatment Implementation [Youth Treatment – Implementation (Short Title –YT-I)] Apply for TI 16 006 Funding Number: TI 16 006 Agency: HHS-SAMHS Category: Health Funding Amount: $800,000 |
| Scholarships for Disadvantaged Students (SDS) Apply for HRSA 16 069 Funding Number: HRSA 16 069 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| Early HIV Treatment to Optimize Patient Health and HIV Prevention Apply for RFA PS 16 006 Funding Number: RFA PS 16 006 Agency: HHS-CDC-HHSCDCERA Category: Health Funding Amount: $495,000 |
| Academic Units for Primary Care Training and Enhancement Apply for HRSA 16 041 Funding Number: HRSA 16 041 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| Administrative Supplements for Complementary Health Practitioner Research Experience (Admin Supp) Apply for PA 16 013 Funding Number: PA 16 013 Agency: HHS-NIH11 Category: Health Funding Amount: $100,000 |
| Supporting the Implementation and Expansion of High Quality, Sustainable and Comprehensive HIV Prevention, Care and Treatment Programs in the Western Region and Turkana County of the Republic of Kenya under the President’s Emergency Plan for AIDS R Apply for CDC RFA GH16 1619 Funding Number: CDC RFA GH16 1619 Agency: HHS-CDC-CGH Category: Health Funding Amount: $103,000,000 |
| NHLBI Clinical Trial Pilot Studies (R34) Apply for PAR 16 037 Funding Number: PAR 16 037 Agency: HHS-NIH11 Category: Health Funding Amount: $225,000 |
| Pulmonary and Cardiovascular Consequences of Inhaled Nicotine (R01) Apply for RFA HL 17 008 Funding Number: RFA HL 17 008 Agency: HHS-NIH11 Category: Health Funding Amount: $300,000 |
| Evaluating the Impact of Non-pharmaceutical Measures on the Incidence of Influenza-like Illness (ILI) among K-12 Students in the United States Apply for RFA CK 16 005 Funding Number: RFA CK 16 005 Agency: HHS-CDC-HHSCDCERA Category: Health Funding Amount: $500,000 |
| Novel Genomic Technology Development Direct to Phase II SBIR (R44) Apply for PAR 16 017 Funding Number: PAR 16 017 Agency: HHS-NIH11 Category: Health Funding Amount: Case Dependent |
| High-End Instrumentation (HEI) Grant Program (S10) Apply for PAR 16 053 Funding Number: PAR 16 053 Agency: HHS-NIH11 Category: Health Funding Amount: $2,000,000 |
| Research on the Epidemiology, Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in Southeast Asia and the Western Pacific Apply for RFA IP 16 001 Funding Number: RFA IP 16 001 Agency: HHS-CDC-HHSCDCERA Category: Health Funding Amount: $3,000,000 |
| Supporting the National Blood Transfusion Service (NBTS) in the implementation and strengthening of Blood Safety activities in the Republic of Uganda under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA PS10 10260501SUPP16 Funding Number: CDC RFA PS10 10260501SUPP16 Agency: HHS-CDC Category: Health Funding Amount: $927,809 |
| National Child Traumatic Stress Initiative – Category III Community Treatment and Services (CTS) Centers Apply for SM 16 005 Funding Number: SM 16 005 Agency: HHS-SAMHS Category: Health Funding Amount: $400,000 |
| Implementation of Programs to Support Integration of Health Information Systems and HIV/AIDS/TB Treatment Services in the Republic of Zambia under the President’s Emergency Plan for AIDS (PEPFAR) Apply for CDC RFA GH16 1669 Funding Number: CDC RFA GH16 1669 Agency: HHS-CDC-CGH Category: Health Funding Amount: $10,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA HL 16 025", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.