Opportunity Information: Apply for RFA HL 09 005

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHLBI Progenitor Cell Biology Consortium Administrative Coordinating Center (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research 93.839 Blood Diseases and Resources Research.
  • This funding opportunity was created on Jan 30, 2009 and posted on Jan 30, 2009.
  • Applicants must submit their applications by May 1, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $600,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Small businesses For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education State governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for RFA HL 09 005

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Opportunity Summary:

This grant opportunity (RFA-HL-09-005) is a National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) funding announcement seeking an organization to serve as the Administrative Coordinating Center (ACC) for the NHLBI Progenitor Cell Biology Consortium. The Consortium itself is built around a set of NHLBI-supported Research Hubs (referenced in a companion announcement, RFA-HL-09-004) that function as "virtual" hubs: clusters of coordinated, synergistic research projects carried out by multidisciplinary teams of principal investigators. The ACC is meant to be the central organizational and operational backbone that helps those distributed Research Hubs function as one integrated program rather than as disconnected projects.

At a program level, the Consortium is focused on major frontiers in progenitor and stem cell biology that are directly relevant to heart, lung, and blood research. Its scientific goals include identifying and characterizing progenitor cell lineages, learning how to control or direct the differentiation of stem and progenitor cells toward specific desired cell fates, and developing strategies to overcome practical and biological hurdles related to transplanting these cells. The emphasis is not only on basic lineage and differentiation biology, but also on translational challenges that arise when moving progenitor-cell-based approaches closer to therapeutic use, particularly issues unique to cell transplantation. In addition to the research projects themselves, the Consortium is described as including core research support facilities and skills development components, implying shared resources and workforce development activities that the ACC would help coordinate across sites.

The funding mechanism is a Cooperative Agreement under the U01 activity code, which generally indicates that NHLBI expects substantial programmatic involvement during the period of performance compared with a standard research project grant. In practical terms, the ACC role is typically expected to coordinate consortium-wide administration, communications, meetings, reporting, and other cross-cutting functions that enable collaboration and consistency across multiple participating research teams and cores. While the summary text does not enumerate specific ACC tasks in detail, the nature of an ACC for a multi-site consortium commonly includes managing schedules and deliverables, facilitating data and material sharing processes, supporting governance structures (committees, working groups), organizing consortium meetings and teleconferences, maintaining shared documentation, and ensuring timely interaction with NHLBI program staff consistent with the cooperative agreement model.

The opportunity is categorized as discretionary funding and lists Health as the primary activity area. It is associated with CFDA numbers 93.837 (Cardiovascular Diseases Research) and 93.839 (Blood Diseases and Resources Research), reflecting NHLBI mission areas connected to the Consortium's stem/progenitor cell emphasis. The announcement indicates no cost-sharing or matching requirement. The award ceiling is listed as $600,000, setting an upper limit on the amount available per award under this solicitation (as presented in the provided source data).

Eligibility is broad and includes a range of domestic organizational types, spanning nonprofit and for-profit entities and academic institutions. Specifically included are nonprofits with and without 501(c)(3) status (other than institutions of higher education), private institutions of higher education, public and state-controlled institutions of higher education, small businesses, and for-profit organizations other than small businesses, as well as state governments. Additional eligible applicants explicitly include Alaska Native and Native Hawaiian Serving Institutions, eligible agencies of the federal government, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). This breadth suggests NHLBI was open to receiving applications from institutions with strong administrative, coordinating, and scientific-program support capacity, not only traditional academic coordinating centers.

Key dates show the announcement was posted and created on January 30, 2009, with an original and current closing date of May 1, 2009, and an archive date of June 1, 2009. The listed agency is NIH, with NHLBI as the institute issuing the call. The primary reference link for the full funding announcement is provided (RFA-HL-09-005), and the notice includes contact guidance directing applicants having technical difficulty accessing the announcement to the NIH Office of Extramural Research (OER) webmaster email.

Frequently Asked Questions (FAQs)

What is this grant opportunity?

This opportunity (RFA-HL-09-005) is a National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) funding announcement seeking an organization to serve as the Administrative Coordinating Center (ACC) for the NHLBI Progenitor Cell Biology Consortium.

Which NIH institute is offering this funding announcement?

The funding announcement is issued by NIH, specifically the National Heart, Lung, and Blood Institute (NHLBI).

What does ACC stand for in this announcement?

ACC stands for Administrative Coordinating Center.

What is the purpose of the Administrative Coordinating Center (ACC)?

The ACC is intended to be the central organizational and operational backbone for the NHLBI Progenitor Cell Biology Consortium, helping the distributed Research Hubs function as one integrated program rather than as disconnected projects.

What is the NHLBI Progenitor Cell Biology Consortium?

The Consortium is built around NHLBI-supported Research Hubs (referenced in a companion announcement, RFA-HL-09-004). These hubs function as "virtual" hubs: clusters of coordinated, synergistic research projects carried out by multidisciplinary teams of principal investigators.

How is the Consortium structured?

The Consortium is organized around multiple distributed, multidisciplinary Research Hubs that operate as "virtual" hubs, plus consortium-wide components such as core research support facilities and skills development elements. The ACC supports coordination across these parts.

Is there a related or companion funding announcement?

Yes. The Research Hubs are referenced as being supported under a companion announcement: RFA-HL-09-004.

What are the main scientific focus areas of the Consortium?

The Consortium focuses on major frontiers in progenitor and stem cell biology directly relevant to heart, lung, and blood research.

What scientific goals are described for the Consortium?

The stated goals include: identifying and characterizing progenitor cell lineages; learning how to control or direct the differentiation of stem and progenitor cells toward desired cell fates; and developing strategies to overcome practical and biological hurdles related to transplanting these cells.

Does the Consortium emphasize translational challenges as well as basic science?

Yes. In addition to basic lineage and differentiation biology, the Consortium emphasizes translational challenges involved in moving progenitor-cell-based approaches closer to therapeutic use, particularly issues unique to cell transplantation.

Are shared resources or workforce development activities included in the Consortium?

Yes. The Consortium is described as including core research support facilities and skills development components, implying shared resources and workforce development activities that the ACC would help coordinate across sites.

What funding mechanism is used for this opportunity?

The funding mechanism is a Cooperative Agreement under the U01 activity code.

What does it mean that this is a Cooperative Agreement (U01)?

Based on the announcement description, a U01 Cooperative Agreement generally indicates NHLBI expects substantial programmatic involvement during the period of performance compared with a standard research project grant.

What kinds of responsibilities are typically associated with the ACC role in a multi-site consortium?

While the summary does not list ACC tasks in exhaustive detail, it describes the ACC as providing central coordination and backbone functions. Common ACC functions for a multi-site consortium include coordinating consortium-wide administration, communications, meetings, reporting, schedules and deliverables; facilitating data and material sharing processes; supporting governance structures (committees and working groups); organizing meetings and teleconferences; maintaining shared documentation; and ensuring timely interaction with NHLBI program staff consistent with the cooperative agreement model.

What is the primary activity area for this opportunity?

The primary activity area listed is Health.

How is the opportunity categorized in terms of funding type?

It is categorized as discretionary funding.

What CFDA numbers are associated with this announcement?

The opportunity is associated with CFDA numbers 93.837 (Cardiovascular Diseases Research) and 93.839 (Blood Diseases and Resources Research).

What is the award ceiling for this solicitation?

The award ceiling is listed as $600,000, which sets an upper limit on the amount available per award under this solicitation (as presented in the provided source data).

Is cost sharing or matching required?

No. The announcement indicates there is no cost-sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes a range of domestic organizational types, including nonprofit and for-profit entities and academic institutions. Specifically included are: nonprofits with and without 501(c)(3) status (other than institutions of higher education); private institutions of higher education; public and state-controlled institutions of higher education; small businesses; for-profit organizations other than small businesses; and state governments.

Are any additional institution types explicitly listed as eligible?

Yes. Additional eligible applicants explicitly include: Alaska Native and Native Hawaiian Serving Institutions; eligible agencies of the federal government; Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).

Does eligibility appear limited to traditional academic coordinating centers?

No. The breadth of eligible applicant types suggests NHLBI was open to applications from institutions with strong administrative, coordinating, and scientific-program support capacity, not only traditional academic coordinating centers.

What are the key dates for this announcement?

The announcement was posted and created on January 30, 2009. The original and current closing date is May 1, 2009. The archive date is June 1, 2009.

Where can applicants find the full funding announcement reference?

The primary reference link is identified as RFA-HL-09-005 (the full funding announcement).

Where can applicants get help if they have technical difficulty accessing the announcement?

The notice directs applicants with technical difficulty accessing the announcement to contact the NIH Office of Extramural Research (OER) webmaster email.

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