Opportunity Information: Apply for PAR 10 285
Apply for PAR 10 285
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHLBI Program Project Applications (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233 National Center on Sleep Disorders Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research.
- This funding opportunity was created on Aug 6, 2013 and posted on Sep 21, 2010.
- Applicants must submit their applications by Aug 6, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,515,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) City or township governments County governments Independent school districts Small businesses For profit organizations other than small businesses Private institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NHLBI Program Project Applications (P01) opportunity (Funding Opportunity Number PAR 10 285) is a discretionary NIH grant announcement from the National Heart, Lung, and Blood Institute that supports large, multi-project research programs built around a shared scientific theme. The main idea is to encourage investigator-initiated teams to propose coordinated sets of studies that are stronger together than they would be as separate, unrelated projects. The scope is broad but clearly tied to the NHLBI mission: research on the biology and diseases of the heart and blood vessels, lung diseases, blood diseases and blood resources, and sleep disorders. The program is positioned as a continuation of NHLBI's long-running P01 program structure described on the NHLBI research mechanisms page, meaning applicants are expected to follow the established NIH/NHLBI expectations for a program project: an integrated program with clear synergy, a unifying central objective, and meaningful collaboration across components.
A defining requirement of this FOA is that each application must contain at least three related research projects. These projects are not meant to be simply bundled under one umbrella; they need to be scientifically connected through a common central theme, focus, and/or overall objective. In practice, that means reviewers will be looking for evidence that the projects inform one another, share conceptual frameworks, and benefit from coordination, such as shared hypotheses, complementary methods, or integrated translational pathways. The P01 mechanism is designed for this kind of team science, typically involving multiple principal investigators or project leaders contributing distinct expertise while working toward an overarching program goal.
The mechanism of support is the NIH Program Project Grant (P01). This mechanism generally supports a program made up of multiple interrelated research projects and often includes shared resources or cores when justified, although the short summary provided here emphasizes the minimum requirement of three related projects rather than listing specific core requirements. The award budget and the number of awards are not fixed in advance in this announcement. Instead, NHLBI indicates that both the total amount awarded and how many awards are made will depend on the number of applications received, their scientific quality, the proposed project durations, and the requested costs. The listing includes an estimated total funding figure of $1,515,000, but the FOA language makes clear that final allocations hinge on the application pool and NHLBI priorities.
The opportunity is categorized under health-related funding activities and is associated with multiple CFDA numbers reflecting the institute's mission areas, including 93.233 (sleep disorders research), 93.837 (cardiovascular diseases research), 93.838 (lung diseases research), and 93.839 (blood diseases and resources research). Cost sharing or matching is not required, which is typical for many NIH research grant mechanisms and reduces the need for applicants to secure non-federal matching funds.
Eligibility is broad and includes many organization types across the nonprofit, academic, governmental, and private sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with and without 501(c)(3) status, small businesses, and for-profit organizations (including those other than small businesses). Government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities are also listed as eligible. Tribal entities are included in multiple forms, such as federally recognized tribal governments and tribal organizations that are not federally recognized. The FOA also explicitly recognizes a range of mission-driven and community-linked institutions and organizations as eligible, including historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This wide eligibility signals NHLBI's openness to strong research programs regardless of institutional type, as long as the applicant can credibly lead a complex, integrated, multi-project research effort.
Key dates in the provided record indicate the announcement was posted September 21, 2010, with an original closing date of September 7, 2013, and an archived date of September 6, 2013. The record also shows a current closing date of August 6, 2013, along with a creation date of August 6, 2013, which reflects the way the listing was captured in the source data rather than changing the overall intent of the FOA. The full announcement is linked through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-10-285.html, and NIH provides webmaster contacts for technical problems accessing or linking to the announcement.
Frequently Asked Questions (FAQs)
What is the NHLBI Program Project Applications (P01) opportunity?
It is a discretionary NIH grant announcement from the National Heart, Lung, and Blood Institute (NHLBI) that supports large, multi-project research programs built around a shared scientific theme. The goal is to fund coordinated sets of studies that are stronger together than they would be as separate, unrelated projects.
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PAR 10 285 (often written as PAR-10-285).
Which NIH institute is offering this opportunity?
The opportunity is offered by the National Heart, Lung, and Blood Institute (NHLBI).
What grant mechanism does this opportunity use?
The mechanism of support is the NIH Program Project Grant (P01).
What kinds of research does NHLBI expect under this P01?
The scope is broad but tied to the NHLBI mission, including research on the biology and diseases of the heart and blood vessels, lung diseases, blood diseases and blood resources, and sleep disorders.
What is the core idea behind a P01 program project in this announcement?
The announcement emphasizes team science: investigator-initiated teams propose coordinated, interrelated research projects that share a unifying central objective and demonstrate meaningful collaboration and synergy across components.
How many research projects are required in a single application?
Each application must contain at least three related research projects.
Do the projects just need to be on a similar topic, or do they need to be integrated?
They need to be integrated. The projects are not meant to be simply bundled under one umbrella; they must be scientifically connected through a common central theme, focus, and/or overall objective, with clear evidence of synergy.
What types of connections between projects does this FOA imply reviewers will look for?
The description indicates reviewers will look for evidence that projects inform one another and benefit from coordination, such as shared hypotheses, complementary methods, integrated conceptual frameworks, or coordinated translational pathways.
Is this opportunity intended for investigator-initiated proposals?
Yes. It is described as encouraging investigator-initiated teams to propose coordinated sets of studies.
Are shared resources or cores required?
The summary notes that P01 programs often include shared resources or cores when justified, but the provided information emphasizes the minimum requirement of three related projects rather than stating specific core requirements.
Is the award budget fixed?
No. The award budget is not fixed in advance. NHLBI indicates the total awarded depends on the number of applications received, their scientific quality, proposed durations, and requested costs.
Is the number of awards predetermined?
No. The number of awards is not fixed and will depend on the application pool and NHLBI considerations described in the announcement summary.
What is the estimated total funding shown in the listing?
The listing includes an estimated total funding figure of $1,515,000, while also noting that final allocations depend on the number and quality of applications, durations, and requested costs.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers aligned with NHLBI mission areas: 93.233 (sleep disorders research), 93.837 (cardiovascular diseases research), 93.838 (lung diseases research), and 93.839 (blood diseases and resources research).
Who is eligible to apply?
Eligibility is broad and includes many organization types across nonprofit, academic, governmental, and private sectors, as listed in the opportunity record.
Are universities eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are nonprofit organizations eligible (including those without 501(c)(3) status)?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status are both listed as eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations are listed as eligible, including small businesses and other for-profit entities (including those other than small businesses).
Are government entities eligible?
Yes. The eligibility list includes state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are Tribal entities eligible?
Yes. The eligibility list includes federally recognized tribal governments and tribal organizations that are not federally recognized.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly listed as eligible.
Are mission-driven institutions like HBCUs and Hispanic-serving institutions eligible?
Yes. The record explicitly recognizes historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions as eligible.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are included in the eligibility list.
Are eligible federal agencies included as applicants?
Yes. Eligible federal agencies are listed among eligible applicants.
When was this opportunity posted?
The record indicates it was posted on September 21, 2010.
What are the closing and archive dates shown in the record?
The record shows an original closing date of September 7, 2013, an archived date of September 6, 2013, and also shows a current closing date of August 6, 2013. The provided information notes these differences reflect how the listing was captured in source data rather than changing the overall intent of the FOA.
Where can applicants find the full announcement text?
The full announcement is linked through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-10-285.html.
What should someone do if they have technical problems accessing or linking to the announcement?
NIH provides webmaster contacts for technical problems accessing or linking to the announcement, as noted in the provided record.
How does NHLBI describe the expected structure of a P01 program in this FOA?
The program is positioned as a continuation of NHLBI's long-running P01 program structure described on the NHLBI research mechanisms page, and applicants are expected to follow established NIH/NHLBI expectations for an integrated program with clear synergy, a unifying central objective, and meaningful collaboration across components.
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