Opportunity Information: Apply for PAR 09 214
Apply for PAR 09 214
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHLBI Systems Biology Collaborations (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233 National Center on Sleep Disorders Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research.
- This funding opportunity was created on Jun 15, 2009 and posted on Jun 15, 2009.
- Applicants must submit their applications by Jan 13, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments Private institutions of higher education County governments State governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NHLBI Systems Biology Collaborations (R01) opportunity (Funding Opportunity Number PAR-09-214) is a National Institutes of Health grant announcement from the National Heart, Lung, and Blood Institute designed to push forward systems biology research related to heart, lung, blood, and sleep (HLBS) health and disease. The main goal is to fund collaborative projects that use systems-level thinking to better explain how normal physiological processes work and how they become disrupted in HLBS diseases and disorders. The emphasis is on research that can integrate complex biological data and mechanisms into coherent, testable models, rather than studying isolated parts of a system in isolation.
A central feature of this program is that it expects genuine collaboration across disciplines, specifically spanning both experimental and computational domains. In practice, that means teams should combine expertise such as laboratory experimentation, physiology, genomics or other high-dimensional measurement approaches, bioinformatics, mathematical modeling, and computational systems analysis. The announcement explicitly highlights that integration across these domains is a critical element of the research plan, and it allows (and implicitly supports) the multiple-Principal Investigator (multi-PI) approach when that structure helps reflect how the work will truly be led and coordinated across specialties.
The funding mechanism is the NIH Research Project Grant (R01). As an R01, the program is aimed at substantial, hypothesis-driven research projects with enough scope to support a coordinated team effort and deliver strong, publishable advances. The notice also makes clear that awards depend on the availability of funds and on receiving a sufficient number of meritorious applications, meaning there is no guaranteed number of awards and proposals will compete based on scientific and technical review.
From an administrative standpoint, this is a discretionary grant opportunity with no cost sharing or matching requirement. It is tied to several NIH/CFDA program areas relevant to HLBS science, including National Center on Sleep Disorders Research (93.233), Cardiovascular Diseases Research (93.837), Lung Diseases Research (93.838), and Blood Diseases and Resources Research (93.839). The opportunity was posted June 15, 2009, with an original and final closing date of January 13, 2012, and it was archived February 13, 2012, indicating it is no longer open but remains important as a reference point for the type of projects NHLBI sought under this initiative.
Eligibility is broad and includes many organization types across the public, private, nonprofit, and governmental spectrum. Eligible applicants listed include for-profit organizations (including small businesses and for-profit entities other than small businesses), nonprofits with or without 501(c)(3) status, public and private institutions of higher education, and multiple levels of government such as city/township, county, state, special district governments, and certain housing authorities. The eligibility language also extends to Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments), independent school districts, and other categories described in the full announcement. Additional eligible groups explicitly called out include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, eligible federal government agencies, and non-U.S. entities (foreign organizations), which signals openness to international participation where appropriate.
For full details, the source announcement was hosted on the NIH grants site at http://grants.nih.gov/grants/guide/pa-files/PAR-09-214.html. The contact information provided is oriented toward technical access issues, directing applicants to the NIH Office of Extramural Research webmaster addresses for help if they had trouble accessing or linking to the full announcement.
FAQs: NHLBI Systems Biology Collaborations (R01) - PAR-09-214
What is the NHLBI Systems Biology Collaborations (R01) opportunity?
It is a National Institutes of Health (NIH) funding opportunity from the National Heart, Lung, and Blood Institute (NHLBI) intended to advance systems biology research related to heart, lung, blood, and sleep (HLBS) health and disease. The Funding Opportunity Number is PAR-09-214.
What is the main purpose of this program?
The program is designed to support collaborative projects that use systems-level approaches to explain how normal physiological processes work and how they become disrupted in HLBS diseases and disorders. A key goal is integrating complex biological data and mechanisms into coherent, testable models rather than focusing on isolated parts of a system.
What research areas does HLBS cover in this announcement?
HLBS refers to heart, lung, blood, and sleep-related health and disease areas that fall within NHLBI's mission and related NIH program areas.
What type of grant mechanism is used?
The funding mechanism is the NIH Research Project Grant (R01).
What kind of projects fit an R01 under this opportunity?
As an R01, the opportunity targets substantial, hypothesis-driven research projects with enough scope to support a coordinated team effort and produce strong, publishable advances.
What makes this opportunity "systems biology" rather than traditional biology?
The emphasis is on systems-level thinking: integrating complex biological measurements and mechanisms into unified, testable models that explain system behavior in health and disease, instead of studying individual components in isolation.
Is collaboration required?
Yes. A central feature is genuine collaboration across disciplines, explicitly spanning both experimental and computational domains. Integration across these domains is described as a critical element of the research plan.
What kinds of expertise are expected on a project team?
The announcement highlights teams that combine capabilities such as laboratory experimentation, physiology, genomics or other high-dimensional measurement approaches, bioinformatics, mathematical modeling, and computational systems analysis.
Does the program allow multiple Principal Investigators (multi-PI)?
Yes. The opportunity allows (and implicitly supports) a multiple-Principal Investigator approach when that structure reflects how the work will truly be led and coordinated across specialties.
Is cost sharing or matching required?
No. This is described as a discretionary grant opportunity with no cost sharing or matching requirement.
Are awards guaranteed?
No. The notice states that awards depend on the availability of funds and on receiving a sufficient number of meritorious applications. There is no guaranteed number of awards, and applications compete through scientific and technical review.
Which NIH/CFDA program areas are associated with this opportunity?
The announcement is tied to NIH/CFDA program areas relevant to HLBS science, including National Center on Sleep Disorders Research (93.233), Cardiovascular Diseases Research (93.837), Lung Diseases Research (93.838), and Blood Diseases and Resources Research (93.839).
When was this funding opportunity posted?
It was posted on June 15, 2009.
What were the application closing dates?
The original closing date and the final closing date were January 13, 2012.
Is this opportunity still open?
No. It was archived on February 13, 2012, indicating it is no longer open. It remains useful as a reference point for the kinds of systems biology collaboration projects NHLBI sought under this initiative.
Who is eligible to apply?
Eligibility is broad and includes many organization types across public, private, nonprofit, and governmental sectors, as described in the full announcement.
Are for-profit organizations eligible?
Yes. Eligible applicants include for-profit organizations, including small businesses and for-profit entities other than small businesses.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are included among eligible applicants.
Are colleges and universities eligible?
Yes. Public and private institutions of higher education are eligible.
Are state and local government entities eligible?
Yes. Eligibility includes several levels of government such as city/township, county, state, special district governments, and certain housing authorities.
Are Native American tribal governments and tribal organizations eligible?
Yes. The eligibility language includes Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments).
Are independent school districts eligible?
Yes. Independent school districts are listed among eligible applicants.
Are minority-serving institutions specifically mentioned?
Yes. The announcement explicitly calls out Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly identified as eligible.
Are regional organizations eligible?
Yes. Regional organizations are included in the eligibility list.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are specifically mentioned as eligible.
Are federal government agencies eligible to apply?
Yes. The eligibility list includes eligible federal government agencies.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-U.S. entities (foreign organizations) are identified as eligible, indicating openness to international participation where appropriate.
Where can I find the official source announcement?
The source announcement was hosted on the NIH grants website at: http://grants.nih.gov/grants/guide/pa-files/PAR-09-214.html
Who should be contacted for help accessing the announcement?
The provided contact information is oriented toward technical access issues and directs users to the NIH Office of Extramural Research webmaster addresses for help if there are problems accessing or linking to the full announcement.
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