Opportunity Information: Apply for PAR 14 070

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Limited Competition Renewal of, and Revisions to, the Alzheimers Disease Genetics Consortium (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
  • This funding opportunity was created on Jan 14, 2014 and posted on Jan 14, 2014.
  • Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

PAR-14-070 is a National Institutes of Health (NIH) funding opportunity announcement from the National Institute on Aging (NIA) that supports a very specific, limited-competition continuation of an existing research effort: the Alzheimers Disease Genetics Consortium. The opportunity is designed for the established NIA Alzheimers Disease Genetics Consortium to apply for either a renewal (continued support for the next project period) and/or a revision (a request to change or expand the scope, aims, or budget of an active award) focused on the genetics of Alzheimers disease. In practical terms, this is not an open call for new, unrelated applicants to form a new consortium; it is intended to maintain momentum and build on prior consortium infrastructure, data resources, and collaborative workflows that NIA has already invested in.

The award mechanism is a U01, which is an NIH cooperative agreement. That detail matters because a cooperative agreement typically means there is substantial scientific or programmatic involvement from NIH staff compared with a standard research project grant. The consortium structure and the cooperative agreement format are generally used when a program depends on coordinated multi-site work, common standards, shared resources, and collective decision-making, all of which are typical for large-scale genetics efforts. The scientific focus is the genetics of Alzheimers disease, which generally encompasses discovery and validation of genetic risk factors, large-scale analyses of genomic data, harmonization of phenotypes and cohorts, and activities that improve the field's ability to identify genetic contributors to disease risk, progression, or related traits.

Administratively, this opportunity sits in the NIH "Health" activity area and is listed under CFDA 93.866 (Aging Research). It is categorized as a discretionary funding opportunity and explicitly states that there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award. The funding announcement was posted and created on January 14, 2014. The original and current closing date is listed as May 7, 2017, and the announcement was archived on June 7, 2017, which signals that the solicitation is no longer active for new submissions after that period.

Eligibility is limited and includes an important restriction on foreign involvement. While the eligibility field is summarized as "Others (see text field entitled Additional Information on Eligibility for clarification)," the included eligibility language makes the constraints clear: non-U.S. entities (foreign institutions) are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined in the NIH Grants Policy Statement are not allowed. In other words, this is intended to be carried out entirely through eligible U.S.-based applicant organizations without foreign institutional participation as formal components of the project.

For applicants or readers seeking the full official announcement text, the opportunity points to the NIH Grants Guide page at http://grants.nih.gov/grants/guide/pa-files/PAR-14-070.html. The contact information provided is primarily technical support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues, rather than a scientific program contact, indicating the summary provided here is more of a top-level listing than a full program narrative. Overall, the main takeaway is that PAR-14-070 was a time-limited, NIA-sponsored, limited-competition cooperative agreement opportunity intended to continue and/or expand the work of the existing Alzheimers Disease Genetics Consortium through renewal and revision applications focused on Alzheimers genetics, under NIH's aging research portfolio.

FAQs: NIH NIA PAR-14-070 (Alzheimers Disease Genetics Consortium - Limited Competition)

What is PAR-14-070?

PAR-14-070 is a National Institutes of Health (NIH) funding opportunity announcement from the National Institute on Aging (NIA) focused on Alzheimer disease genetics. It supports a very specific, limited-competition continuation of an existing effort: the NIA Alzheimer’s Disease Genetics Consortium.

Is this funding opportunity open to new applicants who want to start a new consortium?

No. Based on the description provided, this is not an open call for new, unrelated applicants to form a new consortium. It is intended for the established NIA Alzheimer’s Disease Genetics Consortium to continue building on previously funded infrastructure, data resources, and collaborative workflows.

What types of applications are supported under this opportunity?

The opportunity is designed to support either (1) a renewal application (continued support for the next project period) and/or (2) a revision application (a request to change or expand the scope, aims, or budget of an active award), specifically in the area of Alzheimer’s disease genetics.

What is the award mechanism for PAR-14-070?

The award mechanism is a U01, which is an NIH cooperative agreement. This matters because cooperative agreements typically involve substantial scientific or programmatic involvement from NIH staff compared with standard research project grants.

What does a U01 cooperative agreement imply for how the project is run?

A U01 cooperative agreement format is generally used when the work depends on coordinated multi-site efforts, common standards, shared resources, and collective decision-making. The description indicates this aligns with the consortium structure and large-scale genetics work being supported.

What scientific area does this opportunity focus on?

The scientific focus is the genetics of Alzheimer’s disease. The description notes that this generally includes discovery and validation of genetic risk factors, large-scale analyses of genomic data, harmonization of phenotypes and cohorts, and activities that improve the field’s ability to identify genetic contributors to disease risk, progression, or related traits.

Which NIH institute sponsors this opportunity?

This funding opportunity announcement is from the National Institute on Aging (NIA), part of NIH.

What is the activity area and CFDA listing associated with this opportunity?

It is listed under the NIH “Health” activity area and under CFDA 93.866 (Aging Research).

Is PAR-14-070 a discretionary funding opportunity?

Yes. The description categorizes it as a discretionary funding opportunity.

Is cost sharing or matching required?

No. The opportunity explicitly states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.

Are foreign (non-U.S.) institutions eligible to apply?

No. The eligibility language provided states that non-U.S. entities (foreign institutions) are not eligible to apply.

Can a U.S. organization apply if it has a non-U.S. component?

No. The eligibility restrictions provided state that non-U.S. components of U.S. organizations are not eligible.

Are foreign components allowed in any form on this project?

No. The information provided states that foreign components (as defined in the NIH Grants Policy Statement) are not allowed, indicating the project is intended to be carried out entirely through eligible U.S.-based applicant organizations without foreign institutional participation as formal project components.

When was this funding opportunity posted?

The funding announcement was posted (and created) on January 14, 2014.

What was the closing date for applications?

The original and current closing date is listed as May 7, 2017.

Is this opportunity still active?

No. The announcement was archived on June 7, 2017, which indicates it is no longer active for new submissions after that period.

Where can applicants find the full official announcement text?

The opportunity points to the NIH Grants Guide page: http://grants.nih.gov/grants/guide/pa-files/PAR-14-070.html.

Who is listed as the contact for this opportunity?

The contact information provided is primarily for technical support through the NIH Office of Extramural Research (OER) webmaster, focused on access or linking issues, rather than a scientific program contact.

What is the main purpose of PAR-14-070 in practical terms?

In practical terms, it is intended to maintain momentum and build on prior consortium infrastructure, data resources, and collaborative workflows that NIA has already invested in, through renewal and/or revision applications tied to the existing Alzheimer’s Disease Genetics Consortium.

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