Opportunity Information: Apply for PAR 13 258

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Program Project Applications (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
  • This funding opportunity was created on Jul 2, 2013 and posted on Jul 2, 2013.
  • Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments Small businesses City or township governments Native American tribal governments (Federally recognized) State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIA Program Project Applications (P01) funding opportunity (PAR 13-258) is a National Institutes of Health grant program run by the National Institute on Aging that supports large, multi-project research efforts focused on aging. The intent is to fund investigator-initiated program projects that tackle important questions aligned with the NIA mission, which broadly centers on understanding aging processes, age-related diseases and conditions, and factors that influence health and function across the lifespan. This opportunity is positioned for teams that have a cohesive, integrated research vision and can show that bringing multiple projects together under one umbrella creates added value beyond funding the same work as separate, independent grants.

A core requirement of this FOA is that each application must be structured as a true program project rather than a loose collection of studies. Specifically, the application must include at least three scientifically related research projects that are tied together by a common central theme, focus, and overall objective. The expectation is that the projects are interdependent in a meaningful way, sharing ideas, approaches, resources, data, or models, and that the program structure strengthens the science through collaboration and coordination. In addition to the minimum three research projects, every P01 must include an Administrative Core. This core is responsible for leadership, coordination, and oversight of the entire program project, ensuring the different projects operate as a unified effort with shared goals, consistent management, and effective communication.

From an administrative standpoint, this is a discretionary grant mechanism within the NIH health funding category, and it falls under CFDA 93.866 (Aging Research). The FOA does not require cost sharing or matching, which is typical for many NIH research grants and means applicants are not required to contribute institutional funds as a condition of award (though institutions often provide support in other ways). The opportunity was posted and created on July 2, 2013, with an original and final closing date of September 7, 2016, and it was archived on October 8, 2016. In practical terms, those dates indicate this particular announcement is no longer open for new submissions, but it remains useful as a reference point for the structure and expectations of NIA P01 applications and may have successor announcements with similar requirements.

Eligibility is broad and includes many types of U.S.-based organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses, and other for-profits that are not small businesses), and a range of government entities such as city or township governments, county governments, special district governments, state governments, and certain regional organizations. Tribal governments and tribal organizations are also included, along with public housing authorities/Indian housing authorities and independent school districts. The FOA explicitly notes additional eligible categories such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. U.S. territories or possessions are included as eligible applicants.

At the same time, the eligibility rules clearly restrict foreign participation in key ways. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, the FOA allows foreign components as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain foreign collaborations or elements when scientifically justified and consistent with NIH policy, even though a foreign institution cannot be the applicant of record.

For applicants seeking official details, the full announcement was hosted on the NIH grants policy/guide site (link provided in the source). The contact information included is primarily for technical or access issues related to the electronic announcement, directing users to the NIH Office of Extramural Research (OER) webmaster email. Overall, the opportunity is best understood as support for coordinated, theme-driven, multi-project aging research programs that require formal integration and centralized leadership through an administrative core, with eligibility designed to accommodate a wide range of U.S. research and community organizations while limiting foreign entities to non-applicant roles.

FAQs: NIA Program Project Applications (P01) - PAR 13-258

What is the NIA Program Project Applications (P01) funding opportunity (PAR 13-258)?

PAR 13-258 is a National Institutes of Health (NIH) funding opportunity run by the National Institute on Aging (NIA) that supports large, coordinated, multi-project research efforts focused on aging. It is designed for investigator-initiated program projects where multiple related studies are formally integrated under one overarching research vision.

What is the main purpose of this P01 opportunity?

The intent is to fund investigator-initiated program projects that address important research questions aligned with the NIA mission, including understanding aging processes, age-related diseases and conditions, and factors influencing health and function across the lifespan.

What kind of research structure does NIA expect in a P01 application?

This FOA requires a true program project structure, not a loose bundle of unrelated studies. The projects must be scientifically related and tied together by a common central theme, focus, and overall objective, with meaningful integration across components.

How many research projects are required within a P01 application?

At least three scientifically related research projects are required. These projects must share a common theme and be organized as a coordinated, interdependent program rather than separate stand-alone efforts.

Do the projects have to be interdependent, or can they just be related?

The expectation is that projects are interdependent in a meaningful way. They should share ideas, approaches, resources, data, or models, and the overall program should demonstrate added scientific value from being organized as a single integrated effort.

What is the Administrative Core, and is it required?

An Administrative Core is required for every P01 under this opportunity. It provides leadership, coordination, and oversight for the entire program project, helping ensure that the different research projects function as a unified program with shared goals, consistent management, and effective communication.

What does it mean that this is an NIH discretionary grant mechanism?

It means the award is made through an NIH grant mechanism in the NIH health funding category where funding decisions are made competitively and at the agency's discretion based on the program goals and the merits of applications.

What is the CFDA number associated with this opportunity?

The opportunity is listed under CFDA 93.866, which corresponds to Aging Research.

Is cost sharing or matching required?

No. The FOA states that cost sharing or matching is not required, meaning applicants are not required to contribute institutional funds as a condition of receiving an award.

When was PAR 13-258 posted, and is it still open?

The opportunity was posted and created on July 2, 2013. Its original and final closing date was September 7, 2016, and it was archived on October 8, 2016. Based on those dates, this particular announcement is no longer open for new submissions.

If PAR 13-258 is archived, why is it still useful?

Even though it is no longer open, it can still be used as a reference for understanding the structure and expectations NIA sets for P01 program project applications, and it may be relevant when looking for successor announcements with similar requirements.

What types of organizations are eligible to apply?

Eligibility is broad for U.S.-based organizations. Eligible applicants include public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status); for-profit organizations (including small businesses and other for-profits); and a range of government entities.

Which government entities are listed as eligible applicants?

Eligible government entities include city or township governments, county governments, special district governments, state governments, and certain regional organizations. Tribal governments and tribal organizations are also included, along with public housing authorities/Indian housing authorities and independent school districts.

Are minority-serving institutions and community organizations eligible?

Yes. The FOA explicitly includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also notes faith-based or community-based organizations as eligible.

Are U.S. territories or possessions eligible to apply?

Yes. U.S. territories or possessions are included as eligible applicants.

Can a foreign (non-U.S.) institution apply as the primary applicant?

No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization under this FOA.

Can a non-domestic component of a U.S. organization apply?

No. Non-domestic components of U.S. organizations are also not eligible to apply as the applicant organization under this opportunity.

Are any foreign collaborations allowed at all?

Yes, in a limited way. The FOA allows foreign components as defined in the NIH Grants Policy Statement. In practice, a U.S. applicant may include certain foreign collaborations or elements when scientifically justified and consistent with NIH policy, even though a foreign institution cannot be the applicant of record.

What does NIA mean by "added value" in a P01?

The FOA emphasizes that bringing multiple projects together should create benefits beyond what would happen if the same work were funded as separate, independent grants. This added value can come from collaboration, shared infrastructure, shared resources or data, coordinated planning, and a unified scientific direction supported by centralized leadership.

Where was the official announcement hosted?

The full announcement was hosted on the NIH grants policy/guide site (as referenced in the source information).

Who is listed as the contact for questions?

The contact information provided is primarily for technical or access issues related to the electronic announcement, directing users to the NIH Office of Extramural Research (OER) webmaster email.

Is this opportunity primarily intended for single-lab projects or team-based programs?

It is positioned for teams that can present a cohesive, integrated research vision. The structure requires multiple related projects and an Administrative Core that coordinates them, which aligns with a team-based, program-style approach.

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