Opportunity Information: Apply for PAR 13 254
Apply for PAR 13 254
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIAID Investigator Initiated Program Project Applications (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Jun 28, 2013 and posted on Jun 28, 2013.
- Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: County governments Private institutions of higher education Public and State controlled institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized) Small businesses Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIAID Investigator Initiated Program Project Applications (P01) opportunity (Funding Opportunity Number PAR-13-254) is a discretionary NIH grant announcement from the National Institute of Allergy and Infectious Diseases (NIAID) that supports multi-project, investigator-initiated research programs organized around a unifying scientific theme. The core idea of a P01 is to fund a coordinated set of related research efforts that are stronger together than they would be as separate, stand-alone projects. Under this FOA, applicants are expected to propose an integrated program that advances a common central focus and overall objective, rather than a loose collection of unrelated studies. A key structural requirement is that each application must include at least two related research projects that clearly share the same central theme, focus, and/or overarching goal.
The scientific scope is broad but firmly aligned with the NIAID mission. Proposed programs may address fundamental and mechanistic research on microbes and the diseases they cause, including studies of biology, pathogenesis, and how hosts respond to microbial infection, explicitly including HIV. The FOA also welcomes work on the immune system itself, spanning mechanisms of normal immune function as well as immune dysfunction that leads to major clinical problems such as autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection. In addition to basic and mechanistic studies, the announcement highlights translational research aimed at developing practical countermeasures, including vaccines, therapeutics, and diagnostics to prevent, detect, and treat infectious diseases as well as immune-mediated and allergic conditions. In practice, this means a competitive P01 could range from deep molecular immunology or microbial pathogenesis to programs that connect discovery science with preclinical development or early translational pathways, as long as the proposed projects are genuinely integrated around a coherent program objective.
From an eligibility standpoint, the FOA is open to a wide range of U.S.-based organizations across academic, governmental, nonprofit, and commercial sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status (including those other than universities), small businesses, and for-profit organizations other than small businesses. Governmental entities are also eligible, including state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and various Native American tribal governments and tribal organizations. The eligibility language also explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Foreign institutions (non-U.S. entities) and non-U.S. components of U.S. organizations are not eligible to apply as applicants, but foreign components are allowed under NIH policy as defined in the NIH Grants Policy Statement, which can enable certain international collaborations while keeping the applicant organization U.S.-based.
Administratively, this is a grant mechanism (Funding Instrument Type: Grant) in the health research area (Funding Activity Category: Health) and is associated with CFDA numbers 93.855 (Allergy and Infectious Diseases Research) and 93.856 (Microbiology and Infectious Diseases Research). The announcement specifies that cost sharing or matching is not required, which is typical for many NIH research grants and means applicants generally do not need to commit non-federal funds as a condition of the award. The FOA was posted June 28, 2013, with an original and current closing date of September 7, 2016, and it was archived October 8, 2016, indicating it is no longer open for new submissions under that specific announcement, though similar P01 opportunities may exist under newer NIH/NIAID announcements.
For applicants looking to understand the official requirements and detailed instructions, the FOA points to the full NIH Grants Guide posting at http://grants.nih.gov/grants/guide/pa-files/PAR-13-254.html and provides NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues. Overall, this opportunity was designed for teams ready to build a tightly coordinated, multi-project research program that addresses significant questions in infectious diseases and immunology and, where appropriate, moves discoveries toward vaccines, diagnostics, and therapies relevant to NIAID priorities.
Frequently Asked Questions (FAQs): NIAID Investigator-Initiated Program Project Applications (P01) - PAR-13-254
What is this funding opportunity?
This is a discretionary NIH grant announcement from the National Institute of Allergy and Infectious Diseases (NIAID) titled "Investigator Initiated Program Project Applications (P01)," Funding Opportunity Number PAR-13-254.
What does a P01 (Program Project) award support?
A P01 supports a coordinated, multi-project, investigator-initiated research program organized around a unifying scientific theme. The intent is to fund a set of related research efforts that are stronger together as an integrated program than they would be as separate, stand-alone projects.
What is the core expectation for how the research program is organized?
Applicants are expected to propose an integrated program that advances a common central focus and overall objective. The application should not read like a loose collection of unrelated studies; it should show clear scientific coordination around a coherent program-level goal.
How many research projects must be included in an application?
Each application must include at least two related research projects that clearly share the same central theme, focus, and/or overarching goal.
What scientific areas does this FOA cover?
The scientific scope is broad but aligned with the NIAID mission. It includes fundamental and mechanistic research on microbes and the diseases they cause (including microbial biology and pathogenesis) and how hosts respond to microbial infection, explicitly including HIV.
Does the FOA support immunology research beyond infectious diseases?
Yes. The FOA welcomes work on the immune system itself, including mechanisms of normal immune function and immune dysfunction leading to major clinical problems such as autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection.
Is translational research included, or is this only basic science?
Translational research is explicitly highlighted. The FOA notes translational work aimed at developing practical countermeasures, including vaccines, therapeutics, and diagnostics to prevent, detect, and treat infectious diseases as well as immune-mediated and allergic conditions.
Do proposed projects need to be connected to a single program objective?
Yes. The announcement emphasizes that competitive applications should connect projects through a coherent program objective, demonstrating genuine integration rather than parallel, unrelated studies.
What types of organizations are eligible to apply?
Eligibility is broad for U.S.-based organizations across academic, governmental, nonprofit, and commercial sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses.
Are governmental entities eligible applicants?
Yes. The FOA lists multiple eligible governmental entity types, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are Native American tribal governments and tribal organizations eligible?
Yes. The eligibility language explicitly includes Native American tribal governments (federally recognized and other than federally recognized), Native American tribal organizations, and tribally controlled institutions in multiple categories.
Are certain institution types explicitly included (for example, minority-serving institutions)?
Yes. The FOA explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. The eligibility language explicitly includes faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes. The eligibility list includes eligible federal agencies.
Can a foreign institution apply as the applicant organization?
No. Foreign institutions (non-U.S. entities) and non-U.S. components of U.S. organizations are not eligible to apply as the applicant organization under this FOA.
Are foreign components allowed in the research program?
Yes. While the applicant must be U.S.-based, foreign components are allowed under NIH policy as defined in the NIH Grants Policy Statement, enabling certain international collaborations.
What is the funding instrument type and activity category?
The funding instrument type is a Grant, and the funding activity category is Health.
What CFDA numbers are associated with this opportunity?
This opportunity is associated with CFDA 93.855 (Allergy and Infectious Diseases Research) and CFDA 93.856 (Microbiology and Infectious Diseases Research).
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required, meaning applicants generally do not need to commit non-federal funds as a condition of the award.
When was this FOA posted, and is it still open?
The FOA was posted on June 28, 2013. The original and current closing date is listed as September 7, 2016, and the FOA was archived on October 8, 2016. Based on those dates and the archived status, it is no longer open for new submissions under PAR-13-254.
Where can applicants find the official FOA and full instructions?
The FOA points to the NIH Grants Guide posting at http://grants.nih.gov/grants/guide/pa-files/PAR-13-254.html for official requirements and detailed instructions.
Who is listed for help with access or linking issues to the FOA?
The FOA provides NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
What kind of team or effort is this opportunity designed for?
This opportunity is designed for teams ready to build a tightly coordinated, multi-project research program addressing significant questions in infectious diseases and immunology and, where appropriate, moving discoveries toward vaccines, diagnostics, and therapies relevant to NIAID priorities.
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