Opportunity Information: Apply for PAR 15 031
Apply for PAR 15 031
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIBIB Quantum Program Technological Innovation to Solve a Major Medical or Public Health Challenge (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health.
- This funding opportunity was created on Nov 6, 2014 and posted on Nov 6, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education County governments City or township governments Small businesses State governments Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIBIB Quantum Program Technological Innovation to Solve a Major Medical or Public Health Challenge (U01) is an NIH cooperative agreement opportunity designed to push biomedical technology far beyond incremental improvement. Its central aim is to produce a "quantum" leap over current methods for preventing, detecting, diagnosing, and/or treating a major disease or a significant national public health problem, primarily by developing new biomedical engineering and biomedical imaging technologies. The program is framed around the idea that some of the biggest advances in health come from disruptive tools and platforms rather than small refinements, and it explicitly targets technology development efforts that could create a true paradigm shift in clinical or public health practice.
A key emphasis of the announcement is translation-oriented technology development with a clear end goal: the supported project should develop and prepare a specific, targeted technology so that it is ready to demonstrate clinical efficacy by the end of the Quantum funding period. The opportunity anticipates that achieving this kind of impact often requires concentrating expertise, infrastructure, and funding on a focused milestone-driven project rather than dispersing effort across loosely connected studies. The language highlights historic examples of transformative biomedical technologies that emerged at the intersection of engineering, physical sciences, and life sciences, such as MR imaging, minimally invasive endoscopic devices, cochlear implants, and pacemakers. In that same spirit, this program is intended to catalyze the next generation of breakthrough technologies with similarly broad effects on health outcomes and quality of life.
This funding opportunity (PAR-15-031) uses the U01 mechanism, meaning it is a cooperative agreement. In practice, that signals substantial NIH programmatic involvement during the project, typically through shared oversight, coordination on milestones, and active partnership to keep development aligned with the program's translational and impact-focused objectives. The activity falls under the health category and is associated with CFDA 93.286, Discovery and Applied Research for Technological Innovations to Improve Human Health. Cost sharing or matching is not required.
Eligibility is broad across U.S.-based organizations and government entities, spanning higher education institutions (public and private), nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and a wide range of local, county, state, and special district governments. The announcement also includes various mission-relevant institution types such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities, and faith-based or community-based organizations, as well as eligible federal agencies and U.S. territories or possessions. Foreign organizations and foreign institutions are not eligible to apply directly, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined by the NIH Grants Policy Statement may be allowed, which typically means certain well-justified international collaborations can be included under NIH rules even though the applicant organization must be eligible and primarily U.S.-based.
Administratively, the opportunity was posted and created on November 6, 2014, with an original and final closing date of May 7, 2017, and it was archived on June 7, 2017. While that means the specific solicitation is no longer open, the description is still useful as a reference point for how NIBIB structures high-impact, technology-driven translational programs and what it considers a compelling "quantum" advance: a concentrated, engineering-led development plan aimed at delivering a clinically meaningful breakthrough against a major disease or public health challenge.
FAQs: NIBIB Quantum Program Technological Innovation to Solve a Major Medical or Public Health Challenge (U01) (PAR-15-031)
What is this funding opportunity?
This is an NIH/NIBIB cooperative agreement opportunity called the NIBIB Quantum Program: Technological Innovation to Solve a Major Medical or Public Health Challenge (U01). It is designed to support the development of biomedical engineering and biomedical imaging technologies that can deliver a major, disruptive advance in health care or public health practice rather than an incremental improvement.
What is the central goal of the Quantum Program?
The central goal is to achieve a "quantum" leap over current methods for preventing, detecting, diagnosing, and/or treating a major disease or a significant national public health problem by developing a specific, targeted technology that could shift the existing paradigm.
What kinds of projects does the program prioritize?
The program prioritizes translation-oriented, milestone-driven technology development projects aimed at creating disruptive tools or platforms. The intent is to concentrate expertise, infrastructure, and funding on a focused development plan rather than spreading resources across loosely connected studies.
Does the program support incremental improvements to existing technologies?
Based on the description, the emphasis is on advances that go far beyond incremental improvement. The program is framed around catalyzing technology development that can create a true paradigm shift in clinical or public health practice.
What is meant by a "quantum" leap in this context?
In this context, a "quantum" leap means a disruptive, transformative jump in capability or impact compared to current methods, with the potential to change clinical or public health practice in a meaningful way.
What technology areas are highlighted?
The opportunity primarily targets new biomedical engineering and biomedical imaging technologies. It also emphasizes innovation at the intersection of engineering, physical sciences, and life sciences.
What is the expected end goal by the end of the funding period?
The project is expected to develop and prepare a specific, targeted technology so that it is ready to demonstrate clinical efficacy by the end of the Quantum funding period.
What is a U01, and how does it affect how the project is run?
U01 is a cooperative agreement mechanism. That indicates substantial NIH programmatic involvement during the project, typically including shared oversight, coordination on milestones, and active partnership to keep the work aligned with translational and impact-focused objectives.
How involved is NIH expected to be during the project?
The description indicates "substantial NIH programmatic involvement," which commonly includes coordinated milestone management and active engagement to maintain alignment with the program's translational goals and expected impact.
What health needs is the program intended to address?
It is intended to address major diseases or significant national public health problems by enabling breakthroughs in prevention, detection, diagnosis, and/or treatment through new technology development.
What are examples of the kind of transformative technologies this program is modeled after?
The opportunity references historic examples of transformative biomedical technologies that emerged from cross-disciplinary innovation, including MR imaging, minimally invasive endoscopic devices, cochlear implants, and pacemakers.
What is the funding opportunity number and mechanism?
The funding opportunity is PAR-15-031, and it uses the U01 cooperative agreement mechanism.
What is the CFDA number and program association?
The opportunity is associated with CFDA 93.286, Discovery and Applied Research for Technological Innovations to Improve Human Health.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and government entities. Eligible applicants include institutions of higher education (public and private), nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and many types of U.S. local, county, state, and special district governments.
Are minority-serving and mission-relevant institutions included in the eligible applicant types?
Yes. The eligible institution types explicitly include HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities, and faith-based or community-based organizations, among others.
Are U.S. territories or possessions eligible?
Yes. The announcement includes eligible U.S. territories or possessions.
Are federal agencies eligible to apply?
Yes. The announcement indicates that eligible federal agencies are included among eligible applicants.
Can a foreign organization apply directly?
No. Foreign organizations and foreign institutions are not eligible to apply directly.
Can a U.S. organization include non-U.S. components?
No. Non-U.S. components of U.S. organizations are not eligible. However, the announcement notes that foreign components as defined by the NIH Grants Policy Statement may be allowed, which typically means certain well-justified international collaborations may be included under NIH rules even though the primary applicant organization must be eligible and U.S.-based.
Is this opportunity still open for applications?
No. The opportunity is archived. It was posted and created on November 6, 2014, with an original and final closing date of May 7, 2017, and it was archived on June 7, 2017.
If it is archived, why might this announcement still matter?
Even though it is no longer open, the description is useful as a reference for how NIBIB structures high-impact, technology-driven translational programs and what it considers a compelling "quantum" advance: a concentrated, engineering-led development plan aimed at delivering a clinically meaningful breakthrough against a major disease or public health challenge.
What type of work is this program trying to catalyze?
The program is trying to catalyze next-generation breakthrough technologies with broad effects on health outcomes and quality of life, similar in spirit to earlier disruptive biomedical technologies that reshaped care.
What is the main theme of the program's approach to achieving impact?
The main theme is concentrated, milestone-driven, translation-oriented technology development, supported through a cooperative agreement structure with active NIH involvement to keep the project aligned to high-impact deliverables.
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